Discovering novel ligands for macromolecules using X-ray crystallographic screening

Nature Biotechnology

Volumn 18, Issue 10 SUPPL., 2000, Pages 1105-1108

  Nienaber, Vicki L ^a   Richardson, Paul L ^a   Klighofer, Vered ^a   Bouska, Jennifer J ^a   Giranda, Vincent L ^a   Greer, Jonathan ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; UROKINASE;

ACCURACY; ANALYTIC METHOD; ARTICLE; CRYSTAL STRUCTURE; MACROMOLECULE; OPTICAL RESOLUTION; PRIORITY JOURNAL; SCREENING; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

ADMINISTRATION, ORAL; ANTINEOPLASTIC AGENTS; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; LIGANDS; MACROMOLECULAR SUBSTANCES; MOLECULAR CONFORMATION; NAPHTHALENES; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; URINARY PLASMINOGEN ACTIVATOR;

EID: 0033773899     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/80319     Document Type: Article

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