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Volumn 45, Issue 1, 2010, Pages 11-18

Novel hybrids from lamellarin D and combretastatin A 4 as cytotoxic agents

Author keywords

Anti proliferative; Combretastatin A 4; Cytotoxic; Hybrids; Lamellarin D

Indexed keywords

2 (3 ISOPROPOXY 4 METHOXYPHENYL) 8,9 DIMETHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE; 2 (4 BROMOPHENYL) 8 ISOPROPOXY 9 METHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE; 2 (4 BROMOPHENYL) 8,9 DIMETHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE; 2 (4 CHLOROPHENYL) 8 ISOPROPOXY 9 METHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE; 2 (4 CHLOROPHENYL) 8,9 DIMETHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE; 2 (5 FLUORO 2 ISOPROPOXYPHENYL) 8,9 DIMETHOXY 1 (4 METHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE; 2 (5 FLUORO 2 METHOXYPHENYL) 8 ISOPROPOXY 1 (4 ISOPROPOXY 3 METHOXYPHENYL) 9 METHOXY 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE; 2 (5 FLUORO 2 METHOXYPHENYL) 8,9 DIMETHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE; 2 (5 FLUORO 2 METHOXYPHENYL) 8,9 DIMETHOXY 1 (4 ISOPROPOXY 3 METHOXYPHENYL) 9 METHOXY 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE; 2 [1 (3,4 DIMETHOXYPHENYL) 8,9 DIMETHOXY 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE 2 YL] 4,5 DIMETHOXYPHENYLMETHANESULFONATE; 2 [8 ISOPROPOXY 1 (4 ISOPROPOXY 3 METHOXYPHENYL) 9 METHOXY 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLIN 2 YL] 4,5 DIMETHOXYPHENYLMETHANESULFONATE; 4 [1 (3,4 DIMETHOXYPHENYL) 8,9 DIMETHOXY 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE 2 YL]BENZENE 1,2 DIOL; 4 [8 ISOPROPOXY 1 (4 ISOPROPOXY 3 METHOXYPHENYL) 9 METHOXY 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE 2 YL]BENZENE 1,2 DIOL; 4 [8 ISOPROPOXY 9 METHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE 2 YL]BENZENE 1,2 DIOL; 4 [8 ISOPROPOXY 9 METHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE 2 YL]PHENOL; 4 [8,9 DIMETHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE 2 YL]BENZENE 1,2 DIOL; 4 [8,9 DIMETHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE 2 YL]PHENOL; 4 [8,9 DIMETHOXY 1 (4 METHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE 2 YL]PHENOL; 5 [8 ISOPROPOXY 9 METHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE 2 YL] 2 METHOXYPHENOL; 5 [8,9 DIMETHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE 2 YL] 2 METHOXYPHENOL; 5 [8,9 DIMETHOXY 1 (4 METHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE 2 YL]2 METHOXYPHENOL; 5 ISOPROPOXY 2 [8 ISOPROPOXY 1 (4 ISOPROPOXY 3 METHOXYPHENYL) 9 METHOXY 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE 2 YL] 4 METHOXYPHENYLMETHANESULFONATE; 8 ISOPROPOXY 2 (3 ISOPROPOXY 4 METHOXYPHENYL) 9 METHOXY 1 (3,4,5 TRIMETHOXYPHENYL) 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLINE; COMBRETASTATIN A4 DERIVATIVE; CYTOTOXIC AGENT; LAMELLARIN D DERIVATIVE; PACLITAXEL; UNCLASSIFIED DRUG;

EID: 72049095563     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.09.017     Document Type: Article
Times cited : (65)

References (25)
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    • 72049133205 scopus 로고    scopus 로고
    • . An Oxigene′s report on http://www.oxigene.com/vascular/pipeline.asp (Clinical Research Progress of CA4P, June 2006)
    • . An Oxigene′s report on http://www.oxigene.com/vascular/pipeline.asp (Clinical Research Progress of CA4P, June 2006)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.