A novel high-performance liquid chromatography/mass spectrometry method for improved selective and sensitive measurement of methotrexate polyglutamation status in human red blood cells

Rapid Communications in Mass Spectrometry

Volumn 23, Issue 23, 2009, Pages 3693-3702

  Van Haandel, Leon ^a   Becker, Mara L ^c   Steven Leeder, J ^c   Williams, Todd D ^b   Stobaugh, John F ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b UNIVERSITY OF KANSAS   (United States)

^c CHILDREN S MERCY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLENDING; BLOOD; CELL CULTURE; CELLS; DISEASES; DRUG PRODUCTS; ELECTROSPRAY IONIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ORGANIC SOLVENTS; PATIENT TREATMENT; POSITIVE IONS; PRECIPITATION (CHEMICAL);

ANALYTES; FOLATE ANTAGONISTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRIES; HUMAN RED BLOOD CELL; LOW DOSE; MEASUREMENTS OF; POLYGLUTAMATE; RHEUMATOID ARTHRITIS; SELECTIVE MEASUREMENTS; SENSITIVE MEASUREMENT;

PHASE SEPARATION;

EID: 71949094543     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.4300     Document Type: Article

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