Simultaneous determination of methotrexate and its eight metabolites in human whole blood by capillary zone electrophoresis

Journal of Chromatography A

Volumn 1014, Issue 1-2, 2003, Pages 93-101

  Kuo, Chien Yuan ^a   Wu, Hsin Lung ^a   Kou, Hwang Shang ^a   Chiou, Shyh Shin ^a   Wu, Deng Chyang ^b   Wu, Shou Mei ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Diaminomethylpteroic acid; Hydroxymethotrexate; Methotrexate; Methotrexate polyglutamates; Protriptyline; Validation

Indexed keywords

BLOOD; DERIVATIVES; ELECTROPHORESIS; EXTRACTION; FUSED SILICA; PATIENT MONITORING;

QUANTITATIVE RANGES;

METABOLITES;

2,4 DIAMINO N10 METHYLPTEROIC ACID; 7 HYDROXYMETHOTREXATE; GLUTAMIC ACID DERIVATIVE; METHOTREXATE; METHOTREXATE DERIVATIVE; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ACCURACY; ACUTE LYMPHOBLASTIC LEUKEMIA; BLOOD ANALYSIS; CANCER CHEMOTHERAPY; CANCER PATIENT; CAPILLARY ZONE ELECTROPHORESIS; CASE REPORT; CONFERENCE PAPER; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MONITORING; EXTRACTION; HUMAN; PATIENT MONITORING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

EID: 0142250939     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(03)00776-3     Document Type: Conference Paper

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