Method for the determination of blood methotrexate by high performance liquid chromatography with online post-column electrochemical oxidation and fluorescence detection

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 845, Issue 1, 2007, Pages 164-168

  Li, Hui ^a   Luo, Wenhong ^a   Zeng, Qingyu ^a   Lin, Zhexuan ^a   Luo, Hongjun ^a   Zhang, Yuan ^a  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

HPLC; Methotrexate; Online electrochemical oxidation

Indexed keywords

BLOOD; CENTRIFUGATION; DISEASES; ENZYMES; FLUORESCENCE; FREEZING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHANOL; THAWING;

FLUORESCENCE DETECTION; METHOTREXATE (MTX); ONLINE ELECTROCHEMICAL OXIDATION; RELATIVE STANDARD DEVIATION; RHEUMATOID ARTHRITIS;

BIOMEDICAL ENGINEERING;

ASCORBIC ACID; DICHLOROMETHANE; HYDROCHLORIC ACID; METHANOL; METHOTREXATE; SODIUM HYDROXIDE;

ANALYTIC METHOD; AQUEOUS SOLUTION; ARTICLE; BLOOD CELL; CENTRIFUGATION; CLINICAL ARTICLE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; ELECTROCHEMICAL ANALYSIS; ELECTROCHEMICAL DETECTION; EVAPORATION; FLUORESCENCE; FREEZE THAWING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LOW DRUG DOSE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RHEUMATOID ARTHRITIS; SOLUTION AND SOLUBILITY; STATISTICAL ANALYSIS; SUPERNATANT;

ARTHRITIS, RHEUMATOID; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROCHEMISTRY; FLUORESCENCE; HUMANS; METHOTREXATE; ONLINE SYSTEMS; POLYGLUTAMIC ACID;

EID: 33751511208     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.07.026     Document Type: Article

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