The C. elegans Dosage Compensation Complex Propagates Dynamically and Independently of X Chromosome Sequence

Current Biology

Volumn 19, Issue 21, 2009, Pages 1777-1787

  Ercan, Sevinç ^a   Dick, Lindsay L ^a   Lieb, Jason D ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

DNA

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; HELMINTH DNA;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CAENORHABDITIS ELEGANS; CHEMISTRY; DNA SEQUENCE; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY; X CHROMOSOME; X CHROMOSOME INACTIVATION;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DNA, HELMINTH; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MODELS, GENETIC; SEQUENCE ANALYSIS, DNA; X CHROMOSOME; X CHROMOSOME INACTIVATION;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 71849116882     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2009.09.047     Document Type: Article

References (34)

1. Straub T., and Becker P.B. Dosage compensation: The beginning and end of generalization. Nat. Rev. Genet. 8 (2007) 47-57
2. Meyer B.J., and Casson L.P. Caenorhabditis elegans compensates for the difference in X chromosome dosage between the sexes by regulating transcript levels. Cell 47 (1986) 871-881
3. Csankovszki G., Collette K., Spahl K., Carey J., Snyder M., Petty E., Patel U., Tabuchi T., Liu H., McLeod I., et al. Three distinct condensin complexes control C. elegans chromosome dynamics. Curr. Biol. 19 (2009) 9-19
4. Meyer B.J. Sex in the wormcounting and compensating X-chromosome dose. Trends Genet. 16 (2000) 247-253
5. Hsu D.R., Chuang P.T., and Meyer B.J. DPY-30, a nuclear protein essential early in embryogenesis for Caenorhabditis elegans dosage compensation. Development 121 (1995) 3323-3334
6. Hsu D.R., and Meyer B.J. The dpy-30 gene encodes an essential component of the Caenorhabditis elegans dosage compensation machinery. Genetics 137 (1994) 999-1018
7. Nagy P.L., Griesenbeck J., Kornberg R.D., and Cleary M.L. A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3. Proc. Natl. Acad. Sci. USA 99 (2002) 90-94
8. Simonet T., Dulermo R., Schott S., and Palladino F. Antagonistic functions of SET-2/SET1 and HPL/HP1 proteins in C. elegans development. Dev. Biol. 312 (2007) 367-383
9. Losada A., and Hirano T. Dynamic molecular linkers of the genome: The first decade of SMC proteins. Genes Dev. 19 (2005) 1269-1287
10. Chuang P.T., Albertson D.G., and Meyer B.J. DPY-27: A chromosome condensation protein homolog that regulates C. elegans dosage compensation through association with the X chromosome. Cell 79 (1994) 459-474
11. Chuang P.T., Lieb J.D., and Meyer B.J. Sex-specific assembly of a dosage compensation complex on the nematode X chromosome. Science 274 (1996) 1736-1739
12. Davis T.L., and Meyer B.J. SDC-3 coordinates the assembly of a dosage compensation complex on the nematode X chromosome. Development 124 (1997) 1019-1031
13. Dawes H.E., Berlin D.S., Lapidus D.M., Nusbaum C., Davis T.L., and Meyer B.J. Dosage compensation proteins targeted to X chromosomes by a determinant of hermaphrodite fate. Science 284 (1999) 1800-1804
14. Lieb J.D., Albrecht M.R., Chuang P.T., and Meyer B.J. MIX-1: An essential component of the C. elegans mitotic machinery executes X chromosome dosage compensation. Cell 92 (1998) 265-277
15. Lieb J.D., Capowski E.E., Meneely P., and Meyer B.J. DPY-26, a link between dosage compensation and meiotic chromosome segregation in the nematode. Science 274 (1996) 1732-1736
16. Csankovszki G., McDonel P., and Meyer B.J. Recruitment and spreading of the C. elegans dosage compensation complex along X chromosomes. Science 303 (2004) 1182-1185
17. Jans J., Gladden J.M., Ralston E.J., Pickle C.S., Michel A.H., Pferdehirt R.R., Eisen M.B., and Meyer B.J. A condensin-like dosage compensation complex acts at a distance to control expression throughout the genome. Genes Dev. 23 (2009) 602-618
18. McDonel P., Jans J., Peterson B.K., and Meyer B.J. Clustered DNA motifs mark X chromosomes for repression by a dosage compensation complex. Nature 444 (2006) 614-618
19. Ercan S., Giresi P.G., Whittle C.M., Zhang X., Green R.D., and Lieb J.D. X chromosome repression by localization of the C. elegans dosage compensation machinery to sites of transcription initiation. Nat. Genet. 39 (2007) 403-408
20. Lowden M.R., Meier B., Lee T.W., Hall J., and Ahmed S. End joining at Caenorhabditis elegans telomeres. Genetics 180 (2008) 741-754
21. Blauwkamp T.A., and Csankovszki G. Two classes of dosage compensation complex binding elements along Caenorhabditis elegans X chromosomes. Mol. Cell. Biol. 29 (2009) 2023-2031
22. Lieb J.D., de Solorzano C.O., Rodriguez E.G., Jones A., Angelo M., Lockett S., and Meyer B.J. The Caenorhabditis elegans dosage compensation machinery is recruited to X chromosome DNA attached to an autosome. Genetics 156 (2000) 1603-1621
23. Yonker S.A., and Meyer B.J. Recruitment of C. elegans dosage compensation proteins for gene-specific versus chromosome-wide repression. Development 130 (2003) 6519-6532
24. Shilatifard A. Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation. Curr. Opin. Cell Biol. 20 (2008) 341-348
25. Chua G., Morris Q.D., Sopko R., Robinson M.D., Ryan O., Chan E.T., Frey B.J., Andrews B.J., Boone C., and Hughes T.R. Identifying transcription factor functions and targets by phenotypic activation. Proc. Natl. Acad. Sci. USA 103 (2006) 12045-12050
26. Alekseyenko A.A., Peng S., Larschan E., Gorchakov A.A., Lee O.K., Kharchenko P., McGrath S.D., Wang C.I., Mardis E.R., Park P.J., and Kuroda M.I. A sequence motif within chromatin entry sites directs MSL establishment on the Drosophila X chromosome. Cell 134 (2008) 599-609
27. Straub T., Grimaud C., Gilfillan G.D., Mitterweger A., and Becker P.B. The chromosomal high-affinity binding sites for the Drosophila dosage compensation complex. PLoS Genet. 4 (2008) e1000302
28. Larschan E., Alekseyenko A.A., Gortchakov A.A., Peng S., Li B., Yang P., Workman J.L., Park P.J., and Kuroda M.I. MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism. Mol. Cell 28 (2007) 121-133
29. Sural T.H., Peng S., Li B., Workman J.L., Park P.J., and Kuroda M.I. The MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila melanogaster X chromosome. Nat. Struct. Mol. Biol. 15 (2008) 1318-1325
30. Stiernagle, T. (2006). Maintenance of C. elegans. In WormBook, The C. elegans Research Community, ed. 10.1895/wormbook.1.101.1, http://www.wormbook.org.
31. Selzer R.R., Richmond T.A., Pofahl N.J., Green R.D., Eis P.S., Nair P., Brothman A.R., and Stallings R.L. Analysis of chromosome breakpoints in neuroblastoma at sub-kilobase resolution using fine-tiling oligonucleotide array CGH. Genes Chromosomes Cancer 44 (2005) 305-319
32. Ji X., Li W., Song J., Wei L., and Liu X.S. CEAS: cis-regulatory element annotation system. Nucleic Acids Res. 34 (2006) W551-W554
33. Jiang M., Ryu J., Kiraly M., Duke K., Reinke V., and Kim S.K. Genome-wide analysis of developmental and sex-regulated gene expression profiles in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 98 (2001) 218-223
34. Whittle C.M., McClinic K.N., Ercan S., Zhang X., Green R.D., Kelly W.G., and Lieb J.D. The genomic distribution and function of histone variant HTZ-1 during C. elegans embryogenesis. PLoS Genet. 4 (2008) e1000187