Recruitment and Spreading of the C. elegans Dosage Compensation Complex Along X Chromosomes

Science

Volumn 303, Issue 5661, 2004, Pages 1182-1185

  Csankovszki, Györgyi ^a   McDonel, Patrick ^a   Meyer, Barbara J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOMES; DNA; PROTEINS;

AUTOSOMES; BASE PAIRS;

MICROORGANISMS;

CAENORHABDITIS ELEGANS PROTEIN; CARRIER PROTEIN; CIS ACTING ELEMENT; DNA BINDING PROTEIN; DPY 27 PROTEIN; DPY-27 PROTEIN; NUCLEAR PROTEIN; SDC 3 PROTEIN, C ELEGANS; SDC-3 PROTEIN, C ELEGANS; UNCLASSIFIED DRUG;

CHROMOSOME;

ANIMAL; ARTICLE; AUTOSOME; BASE PAIRING; BINDING SITE; BIOLOGICAL MODEL; CAENORHABDITIS ELEGANS; CHROMOSOME; CHROMOSOME STRUCTURE; COSMID; DOSAGE COMPENSATION COMPLEX; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DOSAGE; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETICS; HERMAPHRODITISM; MALE; METABOLISM; MOLECULAR GENETICS; NONHUMAN; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TRANSGENIC ANIMAL; X CHROMOSOME;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; BINDING SITES; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CARRIER PROTEINS; CHROMOSOMES; COSMIDS; DNA-BINDING PROTEINS; DOSAGE COMPENSATION, GENETIC; FEMALE; HERMAPHRODITISM; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; REPETITIVE SEQUENCES, NUCLEIC ACID; X CHROMOSOME;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 1242329417     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1092938     Document Type: Article

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21. We thank D. Albertson for X chromosome yeast artificial chromosomes; C. Y. Loh for cosmid array yEx708 found to carry an X-recognition element; T. Cline, A. Severson, and C. Tsai for critical comments on the manuscript; and A. Lee, D. Akey, and T. Blumenthal for discussions. Some nematode strains were provided by the Caenorhabditis Genetics Center, funded by NIH's National Center for Research Resources. This work was supported by NIH Grant R37-GM30702 (B.J.M.) and NIH Fellowship F32-GM065007 (G.C.). B.J.M. is an investigator of the Howard Hughes Medical Institute.