Neuroprotective effect of progesterone on acute phase changes induced by partial global cerebral ischaemia in mice

Journal of Pharmacy and Pharmacology

Volumn 60, Issue 6, 2008, Pages 731-737

  Aggarwal, Raman ^a   Medhi, Bikash ^a   Pathak, Ashis ^a   Dhawan, Veena ^a   Chakrabarti, Amitava ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE PEROXIDASE; PENTETRAZOLE; PROGESTERONE; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ACUTE DISEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN WATER; CAROTID ARTERY OBSTRUCTION; CONTROLLED STUDY; DISEASE PREDISPOSITION; DRUG EFFECT; LIPID PEROXIDATION; MALE; MORPHOLOGY; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; SCORING SYSTEM; SEIZURE; TRANQUILIZING ACTIVITY; TREATMENT OUTCOME;

ANIMALS; ANTIOXIDANTS; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; INJECTIONS, INTRAPERITONEAL; LIPID PEROXIDATION; MALE; MICE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PROGESTERONE; PROGESTINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 43949131780     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.60.6.0008     Document Type: Article

References (27)

1. Alonso de Lecinana, M., Diez-Tejedor, E., Cearceller, F., Roda, J. M. (2000) Cerebral ischemia: from animal studies to clinical practice. Should the methods be reviewed? Cerebrovasc. Dis. 11 (Suppl. 1): 20-30
2. Baker, K., Marcus, C. B., Huffman, K. (1998) Synthetic combined super oxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury. J. Pharmacol. Exp. Ther. 284: 215-221
3. Cervantes, M., Gonzalez-Vidal, M. D., Reulas, R. (2002) Neuroprotective effects of progesterone on damage elicited by acute global cerebral ischemia in neurons of the caudate nucleus. Arch. Med. Res. 33: 6-14
4. Chen, J., Chopp, M., Li, Y. (1999) Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat. J. Neurol. Sci. 171: 24-30
5. Dempsey, R. J., Baskaya, M. K., Doglan, A. (2000) Attenuation of brain edema, blood-brain barrier breakdown, and injury volume by ifenprodil, a polyamine-site NMDA receptor antagonist, after experimental traumatic brain injury in rats. Neurosurgery 47: 399-406
6. Easton, J. D., Hansen, S. L., Martin, J. B. (1998) Cerebrovascular diseases. In: Fanci, A. S., Braunwald, E., Isselbacher, K. J., Wilson, J. D., Martin, J. B., Kasper, D. L., Hauser, S. L., Longo D. L., Harrison, D. R. (eds) Harrison's principles of internal medicine, 14th edn. McGraw-Hill, New York, pp 2325-2348
7. Fagan, S. C., Hess, D. C., Hohnadel, E. J., Pollock, D. M., Ergul, A. (2004) Targets for vascular protection after acute ischemic stroke. Stroke 35: 2220-2225
8. Gibson, C. L., Constantin, D., Prior, M. J. (2005) Progesterone suppresses the inflammatory response and nitric oxide synthase-2 expression following cerebral ischemia. Exp. Neurol. 193: 522-530
9. Giorgi, O., Orlandi, M., Lecca, D., Corda, M. G. (1991) MK-801 prevents chemical kindling induced by pentylenetetrazol in rats. Eur. J. Pharmacol. 193: 363-365
10. Himori, N., Wantanabe, H., Akaike, N. (1990) Cerebral ischemia model with conscious mice. Involvement of NMDA receptor activation and derangement of learning and memory ability. J. Pharmacol. Methods 23: 311-327
11. Homi, H. M., Mixco, J. M. (2003) Severe hypertension is not essential for isoflurane neuroprotection against forebrain ischemia in mice. Anesthesiology 99: 1145-1151
12. Jiang, N., Chopp, M., Stein, D., Feit, H. (1996) Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats. Brain Res. 735: 101-107
13. Kono, Y. (1978) Generation of superoxide radical during auto-oxidation of hydroxylamine and assay for SOD. Arch. Biochem. Biophys. 186: 189-195
14. Littleton-Kearney, M. T., Klaus, J. A., Hurn, P. D. (2005) Effects of combined oral conjugated estrogens and medroxyprogesterone acetate on brain infarction size after experimental stroke in rat. J. Cereb. Blood Flow Metab. 25: 421-426
15. Lowry, O. H., Rosebrough, N. J., Farr, A. L., Randall, R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275
16. Luck, H. (1963) Catalase. In: Bergmeyer, H. U. (ed.) Methods of enzymatic analysis. Academic Press, New York, pp 885-894
17. Maguire, J. L., Stell, B. M., Rafizadeh, M., Mody, I. (2005) Ovarian cycle-linked changes in GABA(A) receptors mediating tonic inhibition alter seizure susceptibility and anxiety. Nat. Neurosci. 8: 797-804
18. Neumar, R. W. (2000) Molecular mechanism of ischemic neuronal injury. Ann. Emerg. Med. 36: 483-506
19. Ohkawa, H., Ohishi, N., Yagi, K. (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95: 351-358
20. Osvaldo, C., Goldstein, L. B. (2004) Seizures and epilepsy after ischemic stroke. Stroke 35: 1769-1775
21. Paglia, D. E., Valentine, W. N. (1967) Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 701: 158-169
22. Sayeed, I., Guo, Q., Hoffman, S. W., Stein, D. G. (2006) Allopregnanolone, a progesterone metabolite, is more effective than progesterone in reducing cortical infarct volume after transient middle cerebral artery occlusion. Ann. Emerg. Med. 47: 381-389
23. Traystman, R. J. (2003) Animal models of focal and global cerebral ischemia. Inst. Lab. Anim. Res. 44: 85-101
24. Vogel, H. G., Vogel, W. H. (eds) (2002) Psychotropic and neurotropic activity. In: Drug discovery and evaluation. 2nd edn. Springer-Verlag, Berlin, Heidelberg, Germany, pp 330-565
25. Williams, A. J., Tortella, F. C. (2000) Topographic EEG mapping following experimental stroke in rats and treatment with neuroprotective sodium channel blocker RS100642. Soc. Neurosci. Abstr. 26: 502
26. Williams, A. J., Tortella, F. C. (2002) Neuroprotective effects of sodium channel blocker RS 100642 and attenuation ischemia induced brain seizures in the rat. Brain Res. 932: 45-55
27. Williams, A. J., Lu, X. M., Slusher, B., Tortella, F. C. (2001) Electroencephalogram analysis and neuroprotective profile of the N-acetylated-alpha-linked acidic dipeptidase inhibitor GPI 5232, in normal and brain injured rats. J. Pharmacol. Exp. Ther. 299: 48-57