Ligand effects on cross-linking support a conformational mechanism for serotonin transport

Journal of Biological Chemistry

Volumn 284, Issue 49, 2009, Pages 33807-33814

  Tao, Zhen ^a   Zhang, Yuan Wei ^a   Agyiri, Alice ^a   Rudnick, Gary ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5-HYDROXYTRYPTAMINE (5-HT); AMINOBUTYRIC ACIDS; CYANOGEN BROMIDE; CYSTEINE RESIDUES; LIGAND EFFECT; METHANETHIOSULFONATE; N-TERMINALS; PHENANTHROLINES; SEROTONIN TRANSPORTERS; SYNAPTIC CLEFT; TRANSMEMBRANES;

AMINES; AMINO ACIDS;

CONFORMATIONS;

2 AMINOMETHYL METHANETHIOSULFONIC ACID; COCAINE; CYANOGEN BROMIDE; CYSTEINE; DISULFIDE; IBOGAINE; METHIONINE; SEROTONIN TRANSPORTER; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CROSS LINKING; HUMAN; HUMAN CELL; LIGAND BINDING; MEMBRANE TRANSPORT; MOLECULAR INTERACTION; MOLECULAR MECHANICS; MUTAGENESIS; NEUROTRANSMITTER UPTAKE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN MODIFICATION; PROTEIN STABILITY;

BIOLOGICAL TRANSPORT; CROSS-LINKING REAGENTS; CYANOGEN BROMIDE; CYSTEINE; CYTOPLASM; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; LIGANDS; MEMBRANE TRANSPORT PROTEINS; MUTATION; PROTEIN CONFORMATION; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;

EID: 71749088620     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.071977     Document Type: Article

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