A plausible role of salivary copper in antimicrobial activity of histatin-5-Metal binding and oxidative activity of its copper complex

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 23, 2009, Pages 6709-6712

  Tay, William M ^a   Hanafy, Ahmed I ^b   Angerhofer, Alexander ^c   Ming, Li June ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b Al Azhar University   (Egypt)

^c University of Florida   (United States)

Author keywords

Antibiotic; Catechol; Cobalt; Copper; EPR; Histatin; Metallopeptide; NMR; Oxidation

Indexed keywords

CATECHOL; COPPER; HISTATIN 5;

ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING SITE; DRUG ACTIVATION; ELECTRON SPIN RESONANCE; ENZYME KINETICS; METAL BINDING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATIVE STRESS;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIA; BINDING SITES; COPPER; DRUG DESIGN; FUNGI; HISTATINS; HUMANS; MICROBIAL SENSITIVITY TESTS; ORGANOMETALLIC COMPOUNDS; OXIDATION-REDUCTION; SALIVA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 71749086727     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.09.119     Document Type: Article

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