Zn2+ ions selectively induce antimicrobial salivary peptide histatin- 5 to fuse negatively charged vesicles. Identification and characterization of a zinc-binding motif present in the functional domain

Biochemistry

Volumn 38, Issue 30, 1999, Pages 9626-9633

  Melino, Sonia ^a   Rufini, Stefano ^b   Sette, Marco ^b   Morero, Roberto ^c   Grottesi, Alessandro ^d   Paci, Maurizio ^b   Petruzzelli, Raffaele ^a  

^a UNIVERSITY OF CHIETI   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c UNIVERSIDAD NACIONAL DE TUCUMÁN   (Argentina)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYL SULFOXIDE; HISTATIN; ISOPROTEIN; TRIFLUOROETHANOL; WATER; ZINC ION;

ALPHA HELIX; AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; METAL BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN TERTIARY STRUCTURE; REGULATORY MECHANISM; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; CIRCULAR DICHROISM; HUMANS; LIPOSOMES; MEMBRANE FUSION; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SALIVARY PROTEINS; SEQUENCE ANALYSIS; SOLUTIONS; TRIFLUOROETHANOL; ZINC;

EID: 0033609529     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990212c     Document Type: Article

References (39)

1. Zasloff, M. (1992) Curr. Opin. Immunol. 4, 3-7.
2. Boman, H. G. (1991) Cell 65, 205-207.
3. Shomers, J. P., Tabak, L. A., Levine, M. J., Mandel, I. D., and Hay, D. I. (1982) J. Dent. Res. 61, 397-399.
4. Wong, R. S. C., Hofman, T., and Bennick, A. (1979) J. Biol. Chem. 254, 4800-4808.
5. Oppenheim, F. G., Yang, Y. C., Diamond, R. D., Hyslop, D., Offner, G. D.and Troxler, R. F. (1986) J. Biol. Chem. 261, 1177-1182.
6. Oppenheim, F. G., Xu, T., McMillian, F. M., Levitz, S. M., Diamond, R. D., Offner, G. D., and Troxler, R. F. (1988) J. Biol. Chem. 263, 7472-7477.
7. Troxler, R. F., Offner, G. D., Xu, T., Vanderspek, J. C., and Oppebheim, F. G. (1990) J. Dent. Res. 69, 2-6.
8. Lal, K., Santarpia, R. P., III, Xu, L., Manssurri, F., and Pollock, J. J. (1992) Oral Microbiol. Immunol. 7, 44-50.
9. Oppenheim, F. G., Yang, Y. C., and Troxler R. F. (1985) J. Dent. Res. 64, 239.
10. Raj, P. A., Edgerton, M. E., and Levine, M. J. (1990) J. Biol. Chem. 265, 3898-3905.
11. Bevins, C. L., and Zasloff, M. (1990) Annu. Rev. Biochem. 59, 396-414.
12. Lear, J. D., Wasserman, Z. R., and Degrado, W. F. (1988) Science 240, 1177-1181.
13. Jongeneel, C. V., Bouvier, J., and Bairoch, A. (1989) FEBS Lett. 242, 211-214.
14. Xu, T., Telser, E., Troxler, R. F., and Oppenheim, F. G. (1990) J. Dent. Res. 69, 1717-1723.
15. Merrifield, R. B. (1963) J. Am. Chem. Soc. 85, 2149.
16. Merrifield, R. B., Stewart, J. M., and Jerberg, N. (1966) Anal. Chem. 38, 1905-1914.
17. McFerran, N. V., Walker, B., McGurk, C. D., and Scott, F. C. (1991) Int. J. Pept. Protein Res. 37, 382-387.
18. Huang, C. H. (1969) Biochemistry 8, 344-355.
19. Rufini, S., Pedersen, S. Z., Desideri, A., and Luly, P. (1990) Biochemistry 29, 9644-9651.
20. Kerker, M. (1969) The scattering of light and other electromagnetic radiation, pp 432-433, Accademic Press, New York.
21. Struck, D. K., Hoekstra, D., and Pagano, R. E. (1981) Biochemistry 20, 4093-4099.
22. Chen, Y. H., Yang, J. T., and Chaun, K. H. (1974) Biochemistry 13, 3350-3359.
23. Chang, T. C., Wu, C. S., and Yang, J. T. (1978) Anal. Biochem. 91, 13-31.
24. Marion, D., and Wüthrich, K. (1983) Biochem. Biophys. Res. Commun. 113, 967-974.
25. Braunschweiler, L., and Ernst, R. R. (1983) J. Magn. Reson. 53, 521-528.
26. Bax, A., and Davis, D. G. (1985) J. Magn. Reson. 65, 355-360.
27. Jeener, J., Meier, B. H., Bachmann, P., and Ernst, R. R. (1979) J. Chem. Phys. 71, 4546-4553.
28. Brunger, A. T. (1992) X-PLOR (version 3.1) Manual, Yale University Press, New Haven, CT.
29. Wüthrich, K. (1986) NMR of Proteins and Nucleic Acids, John Wiley & sons, New York.
30. Waterhous, D. V., and Johnson, W. C., Jr. (1994) Biochemistry 33, 2121-2128.
31. Jasanoff, A., and Fersht, A. R. (1994) Biochemistry 33, 2129-2135.
32. Bode, W., Gomis-Ruth, F. X., and Stöckler, W. (1993) FEBS Lett. 331, 134-140.
33. Raj, P. A., Marcus, E., and Sukumaran, D. K. (1998) Biopolymers 45, 51-67.
34. Wishart, D. S., Sykes, B. D., and Richards, F. M. (1992) Biochemistry 31, 1647-1651.
35. Huang, X., Atwood, C. S., Moir, R. D., Hartsborn, M. A., Vonsattle, J. P., Tanzi, R. E., and Bush, A. I. (1997) J. Biol. Chem. 272, 26464-26470.
36. Driscoll, J., Duan, C., Zuo, Y., Xu, T., Troxler, R., and Oppenheim, F. G. (1996) Gene 177, 29-34.
37. Zhuo, Y., Xu, T., Troxler, F., Li, J., Driscoll, J., and Oppenheim, F. G. (1995) Gene 161, 87-91.
38. Ghung, B. H., Anantharamiah, G. M., Brouilette, C. G., Nishida, T., and Segrest, J. P. (1985) J. Biol. Chem. 260, 10256-10262.
39. Fujii, G., Selsted, M. E., and Eisenberg, D. (1993) Protein Sci. 2, 1301-1312.