The cytotoxicity of saponins correlates with their cellular internalization

ChemMedChem

Volumn 2, Issue 3, 2007, Pages 288-291

  Wang, Yibing ^a   Zhang, Yichun ^a   Yu, Biao ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

Cellular internalization; Cytotoxicity; Fluorescent probes; Lysosomes; Spirostan saponin

Indexed keywords

FLUORESCENT DYE; SAPONIN; SPIROSTAN DERIVATIVE;

ANIMAL; ARTICLE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ENDOCYTOSIS; HUMAN; IC 50; LYSOSOME; METABOLISM; NEOPLASM; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL MEMBRANE; ENDOCYTOSIS; FLUORESCENT DYES; HUMANS; INHIBITORY CONCENTRATION 50; LYSOSOMES; MOLECULAR STRUCTURE; NEOPLASMS; SAPONINS; SPIROSTANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 47749156840     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200600235     Document Type: Article

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