The energy landscape of 3-deoxy-D-manno-octulosonate 8-phosphate synthase

Biochemistry

Volumn 48, Issue 49, 2009, Pages 11706-11714

  Tao, Peng ^a,b   Gatti, Domenico L ^a   Bernhard Schlegel, H ^b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; CONCERTED REACTIONS; DIFFERENT MECHANISMS; ENERGY LANDSCAPE; ENZYMATIC REACTION; EXPERIMENTAL OBSERVATION; GRAM-NEGATIVE BACTERIA; HYDROXIDE IONS; INORGANIC PHOSPHATES; OXOCARBENIUM; PHOSPHATE GROUP; PHOSPHOENOLPYRUVATES; POTENTIAL REACTIONS; REACTION ENERGY; REACTION PATHS; SYN-ADDITION; SYNTHASES; TETRAHEDRAL INTERMEDIATES; TRANSIENT INTERMEDIATE; ZWITTERIONIC INTERMEDIATE;

BACTERIA; BIOCHEMISTRY; CONDENSATION; ENZYMES; FLUORINE CONTAINING POLYMERS; POTENTIAL ENERGY; POTENTIAL ENERGY SURFACES; QUANTUM CHEMISTRY;

ADDITION REACTIONS;

3 DEOXY DEXTRO MANNO OCTULOSONATE 8 PHOSPHATE; ENDOTOXIN; LIPOPOLYSACCHARIDE; UNCLASSIFIED DRUG; WATER;

ARTICLE; DRUG STRUCTURE; ENERGY; ENZYME MECHANISM; NONHUMAN; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ALDEHYDE-LYASES; BACTERIAL PROTEINS; CATALYTIC DOMAIN; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; ENERGY METABOLISM; GRAM-NEGATIVE BACTERIA; MODELS, MOLECULAR; PENTOSEPHOSPHATES; PHOSPHOENOLPYRUVATE; QUANTUM THEORY; WATER;

NEGIBACTERIA;

EID: 71649110682     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi901341h     Document Type: Article

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