The role of asparagine-linked glycosylation site on the catalytic domain of matriptase in its zymogen activation

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1804, Issue 1, 2010, Pages 156-165

  Miyake, Yuka ^a   Tsuzuki, Satoshi ^a   Mochida, Seiya ^a   Fushiki, Tohru ^a   Inouye, Kuniyo ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Catalytic domain; Matriptase; N glycosylation site; Protein folding; Zymogen activation

Indexed keywords

ASPARAGINE; ENZYME PRECURSOR; GLUTAMINE; MATRIPTASE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CATALYSIS; CELL SURFACE; ENZYME ACTIVE SITE; ENZYME GLYCOSYLATION; GENETIC TRANSFECTION; HYDROLYSIS; KIDNEY CELL; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

ANIMALS; ASPARAGINE; CATALYTIC DOMAIN; CELL LINE; DOGS; ENZYME ACTIVATION; ENZYME PRECURSORS; GLYCOSYLATION; RATS; SERINE ENDOPEPTIDASES;

RATTUS;

EID: 71649106554     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2009.09.025     Document Type: Article

References (37)

1. Lin C.Y., Tseng I.C., Chou F.P., Su S.F., Chen Y.W., Johnson M.D., and Dickson R.B. Zymogen activation, inhibition, and ectodomain shedding of matriptase. Front. Biosci. 13 (2008) 621-635
2. Darragh M.R., Bhatt A.S., and Craik C.S. MT-SP1 proteolysis and regulation of cell-microenvironment interactions. Front. Biosci. 13 (2008) 528-539
3. Bugge T.H., List K., and Szabo R. Matriptase-dependent cell surface proteolysis in epithelial development and pathogenesis. Front. Biosci. 12 (2007) 5060-5070
4. Zhang T., Cai X., Schlegelberger B., and Zheng S. Assignment1 of human putative tumor suppressor genes ST13 (alias SNC6) and ST14 (alias SNC19) to human chromosome bands 22q13 and 11q24->q25 by in situ hybridization. Cytogenet. Cell Genet. 83 (1998) 56-57
5. Kim M.G., Chen C., Lyu M.S., Cho E.G., Park D., Kozak C., and Schwartz R.H. Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains. Immunogenetics 49 (1999) 420-428
6. Takeuchi T., Shuman M.A., and Craik C.S. Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 11054-11061
7. Satomi S., Yamasaki Y., Tsuzuki S., Hitomi Y., Iwanaga T., and Fushiki T. A role for membrane-type serine protease (MT-SP1) in intestinal epithelial turnover. Biochem. Biophys. Res. Commun. 287 (2001) 995-1002
8. Oberst M.D., Singh B., Ozdemirli M., Dickson R.B., Johnson M.D., and Lin C.Y. Characterization of matriptase expression in normal human tissues. J. Histochem. Cytochem. 51 (2003) 1017-1025
9. List K., Hobson J.P., and Molinolo A. T.H. Bugge Co-localization of the channel activating protease prostasin/(CAP1/PRSS8) with its candidate activator, matriptase. J. Cell. Physiol. 213 (2007) 237-245
10. Cho E.G., Kim M.G., Kim C., Kim S.R., Seong I.S., Chung C., Schwartz R.H., and Park D. N-terminal processing is essential for release of epithin, a mouse type II membrane serine protease. J. Biol. Chem. 276 (2001) 44581-44589
11. Benaud C., Dickson R.B., and Lin C.Y. Regulation of the activity of matriptase on epithelial cell surfaces by a blood-derived factor. Eur. J. Biochem. 268 (2001) 1439-1447
12. Hung R.J., Hsu I., Dreiling J.L., Lee M.J., Williams C.A., Oberst M.D., Dickson R.B., and Lin C.Y. Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts. Am. J. Physiol. Cell Physiol. 286 (2004) C1159-C1169
13. Miyake Y., Yasumoto M., Tsuzuki S., Fushiki T., and Inouye K. Activation of a membrane-bound serine protease matriptase on the cell surface. J. Biochem. 146 (2009) 273-282
14. Wang J.K., Lee M.S., Tseng I.C., Chou F.P., Chen Y.W., Fulton A., Lee H.S., Chen C.J., Johnson M.D., and Lin C.Y. Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition. Am. J. Physiol. Cell Physiol. 297 (2009) C459-C470
15. Lee S.L., Dickson R.B., and Lin C.Y. Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease. J. Biol. Chem. 275 (2000) 36720-36725
16. Takeuchi T., Harris J.L., Huang W., Yan K.W., Coughlin S.R., and Craik C.S. Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates. J. Biol. Chem. 275 (2000) 26333-26342
17. Kojima K., Tsuzuki S., Fushiki T., and Inouye K. The activity of a type II transmembrane serine protease, matriptase, is dependent solely on the catalytic domain. Biosci. Biotechnol. Biochem. 73 (2008) 454-456
18. Mochida S., Tsuzuki S., Yasumoto M., Inouye K., and Fushiki T. Secreted expression of pseudozymogen forms of recombinant matriptase in Pichia pastoris. Enzyme Microb. Technol. 45 (2009) 288-294
19. List K., Haudenschild C.C., Szabo R., Chen W., Wahl S.M., Swaim W., Engelholm L.H., Behrendt N., and Bugge T.H. Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis. Oncogene 21 (2002) 3765-3779
20. List K., Szabo R., Wertz P.W., Segre J., Haudenschild C.C., Kim S.Y., and Bugge T.H. Loss of proteolytically processed filaggrin caused by epidermal deletion of matriptase/MT-SP1. J. Cell Biol. 163 (2003) 901-910
21. Oberst M.D., Williams C.A., Dickson R.B., Johnson M.D., and Lin C.Y. The activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitor. J. Biol. Chem. 278 (2003) 26773-26779
22. Oberst M.D., Chen L.Y.L., Kiyomiya K., Williams C.A., Lee M.S., Johnson M.D., Dickson R.B., and Lin C.Y. HAI-1 regulates activation and expression of matriptase, a membrane-bound serine protease. Am. J. Physiol. Cell Physiol. 289 (2005) C462-C470
23. Désilets A., Béliveau F., Vandal G., McDuff F.O., Lavigne P., and Leduc R. Mutation of G827R in matriptase causing autosomal recessive ichthyosis with hypotrichosis yields an inactive protease. J. Biol. Chem. 283 (2008) 10535-10542
24. Friedrich R., Fuentes-Prior P., Ong E., Coombs G., Hunter M., Oehler R., Pierson D., Gonzalez R., Huber R., Bode W., and Madison E.L. Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase. J. Biol. Chem. 277 (2002) 2160-2168
25. Helenius A., and Aebi M. Roles of N-linked glycans in the endoplasmic reticulum. Annu. Rev. Biochem. 73 (2004) 1019-1049
26. Jones J., Krag S.S., Michael J., and Betenbaugh M.J. Controlling N-linked glycan site occupancy. Biochim. Biophys. Acta 1726 (2005) 121-137
27. Gladysheva I.P., King S.M., and Houng A.K. N-glycosylation modulates the cell-surface expression and catalytic activity of corin. Biochem. Biophys. Res. Commun. 373 (2008) 130-135
28. Murai N., Miyake Y., Tsuzuki S., Inouye K., and Fushiki T. Involvement of the cytoplasmic juxtamembrane region of matriptase for its exclusive localization to the basolateral membrane domain of Madin-Darby canine kidney epithelial cells. Cytotechnology (2009) 10.1007/s10616-009-9205-0
29. Kojima K., Tsuzuki S., Fushiki T., and Inouye K. Role of the stem domain of matriptase in the interaction with its physiological inhibitor, hepatocyte growth factor activator inhibitor type I. J. Biochem. 145 (2009) 783-790
30. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
31. Tsuzuki S., Murai N., Miyake Y., Inouye K., Hirayasu H., Iwanaga T., and Fushiki T. Evidence for the occurrence of membrane-type serine protease 1/matriptase on the basolateral sides of enterocytes. Biochem. J. 388 (2005) 679-687
32. Kojima K., Tsuzuki S., Fushiki T., and Inouye K. Roles of functional and structural domains of hepatocyte growth factor activator inhibitor type 1 in the inhibition of matriptase. J. Biol. Chem. 283 (2008) 2478-2487
33. Y. Miyake, S. Tsuzuki, M. Yasumoto, T. Fushiki, K. Inouye, Requirement of the activity of hepatocyte growth factor activator inhibitor type 1 for the extracellular appearance of a transmembrane serine protease matriptase in monkey kidney COS-1 cells, Cytotechnology, doi:10.1007/s10616-009-9219-7.
34. Kilpatrick L.M., Harris R.L., Owen K.A., Bass R., Ghorayeb C., Bar-Or A., and Ellis V. Initiation of plasminogen activation on the surface of monocytes expressing the type II transmembrane serine protease matriptase. Blood 108 (2006) 2616-2623
35. Lin C.Y., Wang J.K., Torri J., Dou L., Sang Q.A., and Dickson R.B. Characterization of a novel, membrane-bound, 80-kDa matrix-degrading protease from human breast cancer cells. J. Biol. Chem. 272 (1997) 9147-9152
36. Lin C.Y., Anders J., Johnson M.D., and Dickson R.B. Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk. J. Biol. Chem. 274 (1999) 18237-18242
37. Caramelo J.J., and Parodi A.J. Getting in and out from calnexin/calreticulin cycles. J. Biol. Chem. 283 (2008) 10221-10225