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Volumn 28, Issue 1, 2010, Pages 8-12

Oral N-acetylcysteine has a deleterious effect in acute iron intoxication in rats

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; FERROUS SULFATE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; URIC ACID;

EID: 71649106059     PISSN: 07356757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajem.2008.09.012     Document Type: Article
Times cited : (7)

References (31)
  • 1
    • 0028144471 scopus 로고
    • Recent increases in numbers and risk of fatalities in young children ingesting iron preparations
    • Berkovitch M., Matsui D., Lamm S.H., et al. Recent increases in numbers and risk of fatalities in young children ingesting iron preparations. Vet Hum Toxicol 36 (1994) 53-55
    • (1994) Vet Hum Toxicol , vol.36 , pp. 53-55
    • Berkovitch, M.1    Matsui, D.2    Lamm, S.H.3
  • 2
    • 0027181122 scopus 로고
    • 1992 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System
    • Litovitz T.L., Holm K.C., Clancy C., et al. 1992 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med 11 (1993) 494-555
    • (1993) Am J Emerg Med , vol.11 , pp. 494-555
    • Litovitz, T.L.1    Holm, K.C.2    Clancy, C.3
  • 4
    • 0023555692 scopus 로고
    • Management of iron overload in the pediatric patient
    • Cohen A.R. Management of iron overload in the pediatric patient. Hematol Oncol Clin North Am 1 (1987) 521-544
    • (1987) Hematol Oncol Clin North Am , vol.1 , pp. 521-544
    • Cohen, A.R.1
  • 5
    • 0029975778 scopus 로고    scopus 로고
    • Insufficient stocking of poisoning antidotes in hospital pharmacies
    • Dart R.C., Stark Y., Fulton B., et al. Insufficient stocking of poisoning antidotes in hospital pharmacies. JAMA 276 (1996) 1508-1510
    • (1996) JAMA , vol.276 , pp. 1508-1510
    • Dart, R.C.1    Stark, Y.2    Fulton, B.3
  • 6
    • 0024262737 scopus 로고
    • Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985)
    • Smilkstein M.J., Knapp G.L., Kulig K.W., and Rumack B.H. Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985). N Engl J Med 319 (1988) 1557-1562
    • (1988) N Engl J Med , vol.319 , pp. 1557-1562
    • Smilkstein, M.J.1    Knapp, G.L.2    Kulig, K.W.3    Rumack, B.H.4
  • 7
    • 0030071905 scopus 로고    scopus 로고
    • N-acetylcysteine increases the glutathione content and protects rat alveolar type II cells against paraquat-induced cytotoxicity
    • Hoffer E., Baum Y., Tabak A., and Taitelman U. N-acetylcysteine increases the glutathione content and protects rat alveolar type II cells against paraquat-induced cytotoxicity. Toxicol Lett 84 (1996) 7-12
    • (1996) Toxicol Lett , vol.84 , pp. 7-12
    • Hoffer, E.1    Baum, Y.2    Tabak, A.3    Taitelman, U.4
  • 8
    • 0024205742 scopus 로고
    • Acetylcysteine: a drug thatis much more than a mucokinetic
    • Zimet I. Acetylcysteine: a drug thatis much more than a mucokinetic. Biomed Pharmacother 42 (1988) 513-520
    • (1988) Biomed Pharmacother , vol.42 , pp. 513-520
    • Zimet, I.1
  • 9
    • 0034691822 scopus 로고    scopus 로고
    • Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine
    • Tepel M., Van Der Giet M., Schwarzfeld C., et al. Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine. N Engl J Med 343 (2000) 180-184
    • (2000) N Engl J Med , vol.343 , pp. 180-184
    • Tepel, M.1    Van Der Giet, M.2    Schwarzfeld, C.3
  • 10
    • 0035666707 scopus 로고    scopus 로고
    • Hepatotoxicity in acute iron poisoning
    • Tenenbein M. Hepatotoxicity in acute iron poisoning. J Toxicol Clin Toxicol 39 (2001) 721-726
    • (2001) J Toxicol Clin Toxicol , vol.39 , pp. 721-726
    • Tenenbein, M.1
  • 11
    • 0016808878 scopus 로고
    • Transfusional iron overload: The relationship between tissue iron concentration and hepatic fibrosis in thalassemia
    • Risdon R.A., Barry M., and Flynn D.M. Transfusional iron overload: The relationship between tissue iron concentration and hepatic fibrosis in thalassemia. J Pathol 116 (1975) 83-95
    • (1975) J Pathol , vol.116 , pp. 83-95
    • Risdon, R.A.1    Barry, M.2    Flynn, D.M.3
  • 12
    • 0026601599 scopus 로고
    • Liver pathology in genetic hemochromatosis: a review of 135 homozygous cases and their bioclinical correlations
    • Deugnier Y.M., Loreal O., Turlin B., et al. Liver pathology in genetic hemochromatosis: a review of 135 homozygous cases and their bioclinical correlations. Gastroenterol 102 (1992) 2050-2059
    • (1992) Gastroenterol , vol.102 , pp. 2050-2059
    • Deugnier, Y.M.1    Loreal, O.2    Turlin, B.3
  • 13
    • 0025157647 scopus 로고
    • The pathology of hepatic iron overload. A free radical mediated process?
    • Bacon B.R., and Britton R. The pathology of hepatic iron overload. A free radical mediated process?. Hepatology 11 (1990) 127-137
    • (1990) Hepatology , vol.11 , pp. 127-137
    • Bacon, B.R.1    Britton, R.2
  • 14
    • 0022529172 scopus 로고
    • Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts
    • Halliwell B., and Gutteridge J.M.C. Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts. Arch Biochem Biophys 246 (1986) 501-514
    • (1986) Arch Biochem Biophys , vol.246 , pp. 501-514
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 15
    • 8944260409 scopus 로고    scopus 로고
    • Efficacy of deferiprone in the treatment of acute iron intoxication in rats
    • Fassos F.F., Berkovitch M., Daneman N., et al. Efficacy of deferiprone in the treatment of acute iron intoxication in rats. J Toxicol Clin Toxicol 34 (1996) 279-289
    • (1996) J Toxicol Clin Toxicol , vol.34 , pp. 279-289
    • Fassos, F.F.1    Berkovitch, M.2    Daneman, N.3
  • 16
    • 0030865654 scopus 로고    scopus 로고
    • Acute iron intoxication: significant differences between sexes
    • Berkovitch M., Livne A., Lushkov G., et al. Acute iron intoxication: significant differences between sexes. Vet Hum Toxicol 39 (1997) 265-267
    • (1997) Vet Hum Toxicol , vol.39 , pp. 265-267
    • Berkovitch, M.1    Livne, A.2    Lushkov, G.3
  • 17
    • 0017347447 scopus 로고
    • International committee for standardization in hematology: recommended methods for red-cell enzyme analysis
    • Beutler E., Blume K.G., Kaplan J.C., et al. International committee for standardization in hematology: recommended methods for red-cell enzyme analysis. Br J Haematol 35 (1977) 331-340
    • (1977) Br J Haematol , vol.35 , pp. 331-340
    • Beutler, E.1    Blume, K.G.2    Kaplan, J.C.3
  • 18
    • 73649194769 scopus 로고
    • Improved method for the determination of blood glutathione
    • Beutler E., Duron O., and Kelly B.M. Improved method for the determination of blood glutathione. J Lab Clin Med 61 (1963) 882-890
    • (1963) J Lab Clin Med , vol.61 , pp. 882-890
    • Beutler, E.1    Duron, O.2    Kelly, B.M.3
  • 20
    • 0035015201 scopus 로고    scopus 로고
    • Glutathione protects chemokine scavenging and antioxidative defense functions in human RBCs
    • Dumaswala U.J., Zhuo L., Mahajan S., et al. Glutathione protects chemokine scavenging and antioxidative defense functions in human RBCs. Am J Physiol Cell Physiol 280 (2001) C867-C873
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Dumaswala, U.J.1    Zhuo, L.2    Mahajan, S.3
  • 21
    • 49149136604 scopus 로고
    • Metabolism and function of glutathione
    • Meister A. Metabolism and function of glutathione. Trends Biochem Sci 6 (1981) 231-233
    • (1981) Trends Biochem Sci , vol.6 , pp. 231-233
    • Meister, A.1
  • 22
    • 17044455494 scopus 로고    scopus 로고
    • Toxicokinetics and toxicodynamics of iron poisoning
    • Tenenbein M. Toxicokinetics and toxicodynamics of iron poisoning. Toxicol Lett 102-103 (1998) 653-666
    • (1998) Toxicol Lett , vol.102-103 , pp. 653-666
    • Tenenbein, M.1
  • 23
    • 0026065487 scopus 로고
    • Iron and the liver
    • Bonkovsky H.L. Iron and the liver. Am J Med Sci 301 (1991) 32-43
    • (1991) Am J Med Sci , vol.301 , pp. 32-43
    • Bonkovsky, H.L.1
  • 24
  • 25
    • 0036521856 scopus 로고    scopus 로고
    • Antioxidant and pro-oxidant effect of the thiolic compounds N-acetylcysteine radical-induced lipid peroxidation
    • Sagrista M.L., Garcia A.F., Madariaga M.A., et al. Antioxidant and pro-oxidant effect of the thiolic compounds N-acetylcysteine radical-induced lipid peroxidation. Free Radic Res 36 (2002) 329-340
    • (2002) Free Radic Res , vol.36 , pp. 329-340
    • Sagrista, M.L.1    Garcia, A.F.2    Madariaga, M.A.3
  • 26
    • 1842601105 scopus 로고    scopus 로고
    • N-acetylcysteine decreases lactate signal intensities in liver tissue and improves liver function in septic shock patients, as shown by magnetic resonance spectroscopy: extended case report
    • Hein O.V., Ohring R., Schilling A., et al. N-acetylcysteine decreases lactate signal intensities in liver tissue and improves liver function in septic shock patients, as shown by magnetic resonance spectroscopy: extended case report. Crit Care 8 (2004) R66-R71
    • (2004) Crit Care , vol.8
    • Hein, O.V.1    Ohring, R.2    Schilling, A.3
  • 27
    • 4444227435 scopus 로고    scopus 로고
    • N-acetylcysteine in intestinal reperfusion injury: an experimental study in rats
    • Hazinedaroglu S.M., Dulger F., Kayaogolu H.A., et al. N-acetylcysteine in intestinal reperfusion injury: an experimental study in rats. ANZ J Surg 74 (2004) 676-678
    • (2004) ANZ J Surg , vol.74 , pp. 676-678
    • Hazinedaroglu, S.M.1    Dulger, F.2    Kayaogolu, H.A.3
  • 28
    • 0029890763 scopus 로고    scopus 로고
    • Improvement of hepatic microhemodynamics by N-acetylcysteine after warm ischemia
    • Koeppel T.A., Thies J.C., Lehmann T., and Gebhar M.M. Improvement of hepatic microhemodynamics by N-acetylcysteine after warm ischemia. Eur Surg Res 28 (1996) 270-277
    • (1996) Eur Surg Res , vol.28 , pp. 270-277
    • Koeppel, T.A.1    Thies, J.C.2    Lehmann, T.3    Gebhar, M.M.4
  • 29
    • 0031916462 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine on hepatic blood flow and function {letter}
    • Ott P. Effects of N-acetylcysteine on hepatic blood flow and function {letter}. Crit Care Med 26 (1998) 415
    • (1998) Crit Care Med , vol.26 , pp. 415
    • Ott, P.1
  • 30
    • 0029004380 scopus 로고
    • Low serum alkaline phosphatase activity associated with severe Wilson's disease. Is the breakdown of alkaline phosphatase molecules caused by reactive oxygen species?
    • Hoshino T., Kumasaka K., Kawano K., et al. Low serum alkaline phosphatase activity associated with severe Wilson's disease. Is the breakdown of alkaline phosphatase molecules caused by reactive oxygen species?. Clin Chim Acta 238 (1995) 91-100
    • (1995) Clin Chim Acta , vol.238 , pp. 91-100
    • Hoshino, T.1    Kumasaka, K.2    Kawano, K.3
  • 31
    • 0023179937 scopus 로고
    • Gastrointestinal metabolism of N-acetylcysteine in the rat, including an assay for sulfite in biological systems
    • Cotgreave I.A., Berggren M., Jones T.W., Dawson J., and Moldeus P. Gastrointestinal metabolism of N-acetylcysteine in the rat, including an assay for sulfite in biological systems. Biopharm Drug Dispos 8 (1987) 377-386
    • (1987) Biopharm Drug Dispos , vol.8 , pp. 377-386
    • Cotgreave, I.A.1    Berggren, M.2    Jones, T.W.3    Dawson, J.4    Moldeus, P.5


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