Vascular endothelial growth factor in Alzheimer's disease and experimental cerebral ischemia

Molecular Brain Research

Volumn 62, Issue 1, 1998, Pages 101-105

  Kalaria, R N ^a   Cohen, D L ^a   Premkumar, D R D ^a   Nag, S ^b   Lamanna, J C ^a   Lust, W D ^a  

^a Departments of Neurology   (United States)

^b TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

Alzheimer's disease; Astrocyte; Glioblastoma multiforme; Growth factor; Hypoxia; Immunocytochemistry; Ischemia; Vascular endothelial growth factor; Vascular smooth muscle cell

Indexed keywords

VASCULOTROPIN;

AGED; ALZHEIMER DISEASE; ANGIOGENESIS; ARTICLE; ASTROCYTOSIS; BRAIN HYPOXIA; BRAIN ISCHEMIA; HUMAN; HUMAN TISSUE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; TISSUE DISTRIBUTION;

ADULT; AGED; ALZHEIMER DISEASE; ANIMALS; BRAIN ISCHEMIA; ENDOTHELIAL GROWTH FACTORS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOKINES; MACACA MULATTA; MALE; MIDDLE AGED; RATS; RATS, INBRED SHR; RATS, WISTAR; TEMPORAL LOBE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0032512124     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(98)00190-9     Document Type: Article

References (27)

1. Berkman R.A., Merrill M.J., Reinhold W.C., Monacci W.T., Saxena A., Clark W.C., Robertoson J.T., Ali I.U., Oldfield E.H. Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms. J. Clin. Invest. 91:1993;153-159.
2. Connolly D.T. Vascular permeability factor: a unique regulator of blood vessel function. J. Cell. Biochem. 47:1991;219-223.
3. Ferrara N., Houck K., Jakeman L., Leung D.W. Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocr. Rev. 13:1992;18-32.
4. Fillit H., Ding W.H., Buee L., Kalman J., Altstiel L., Lawlor B., Wolf-Klein G. Elevated circulating tumor necrosis factor levels in Alzheimer's disease. Neurosci. Lett. 129:1991;318-320.
5. Goldberg M.A., Schneider T.J. Similarities between the oxygen-sensing mechanism regulating the expression of vascular endothelial growth factor and erythropoietin. J. Biol. Chem. 269:1994;4355-4359.
6. Gray C.W., Patel A.J. Regulation of beta-amyloid precursor protein isoform mRNAs by transforming growth factor-beta 1 and interleukin-1 beta in astrocytes. Mol. Brain Res. 19:1993;25-256.
7. Griffin W.S.T., Stanley L., Ling C., White L., Macleod V., Perrot L.J., White C.L. III, Araoz C. Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 86:1989;7611-7615.
8. Kalaria R.N. The blood-brain barrier and cerebral microcirculation in Alzheimer's disease. Cerebrovasc. Brain Metab. Rev. 4:1992;226-260.
9. Kalaria R.N. Cerebral vessels in ageing and Alzheimer's disease. Pharm. Therap. 72:1996;193-214.
10. Kalaria R.N., Kroon S.N. Expression of leukocyte antigen CD34 by brain capillaries in Alzheimer's disease and neurologically normal subjects. Acta Neuropathol. 84:1992;606-612.
11. Kalaria R.N., Bhatti S.U., Palatinsky E.A., Pennington D.H., Shelton E.R., Chan H.W., Perry G., Lust W.D. Accumulation of the ß amyloid precursor protein at sites of ischemic injury in rat brain. NeuroReport. 4:1993;211-214.
12. Kalaria R.N., Pax A.B., Premkumar D.R.D., Lieberburg I. Production and increased detection of amyloid ß-protein and amyloidogenic fragments in brain microvessels, meningeal vessels and choroid plexus in Alzheimer disease. Mol. Brain Res. 35:1995;58-68.
13. Kalaria R.N., Cohen D.L., Al-Mudallal A.S., Lust W.D., Premkumar D.R.D. VEGF/VPF expression in ischemic brain injury and human neurodegenerative disorders. J. Cereb. Blood Flow Metab. 15:1995;S599.
14. LaManna J.C., Vendel L.M., Farrell R.N. Brain adaptation to chronic hypobaric hypoxia in rats. J. Appl. Physiol. 72:1992;2238-2243.
15. Masliah E., Mallory M., Alford M., Deteresa R., Saitoh T. PDGF is associated with neuronal and glial alterations of Alzheimer's disease. Neurobiol. Aging. 16:1995;549-556.
16. McComb R.D., Miller K.A., Carson S.D. Tissue factor antigen in senile plaques of Alzheimer's disease. Am. J. Pathol. 139:1991;491-494.
17. Monacci W.T., Merrill M.J., Oldfield E.H. Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues. Am. J. Physiol. 264:1993;C995-C1002.
18. Pe'er J., Shweiki D., Itin A., Hemo I., Gnessin H., Keshet E. Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases. Lab. Invest. 72:1995;638-645.
19. Plate K.H., Breier G., Weich H.A., Risau W. Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo. Nature. 359:1992;845-848.
20. Premkumar D.R.D., Cohen D.L., Hedera P., Friedland R.P., Kalaria R.N. Apolipoprotein E ε4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology in Alzheimer's disease. Am. J. Pathol. 148:1996;2083-2095.
21. Shweiki D., Itin A., Soffer D., Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature. 359:1992;843-845.
22. Stopa E.G., Gonzalez A.M., Chorsky R., Corona R.J., Alvarez J., Bird E.D., Baird A. Basic fibroblast growth facto in Alzheimer's disease. Biochem. Biophys. Res. Commun. 171:1990;690-696.
23. Styren S.D., Mufson E.J., Styren G.C., Civin W.H., Rogers J. Epidermal growth factor receptor expression in demented and aged human brain. Brain Res. 347:1990;347-352.
24. Tischer E., Mitchell R., Hartman T., Silva M., Gospodarowicz D., Fiddes J.C., Abraham J. The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon slicing. J. Biol. Chem. 266:1991;11947-11954.
25. M.H. Tuszynski, F.H. Gage, Neurotrophic factors and neuronal loss: potential relevance to Alzheimer disease, in: R.D. Terry, R. Katzman, K.L. Bick, (Eds.), Alzheimer Disease. Raven Press, New York, 1994, pp. 405-417.
26. van der Wal E.A., Gomez-Pinilla F., Cotman C.W. Transforming growth factor-beta 1 is in plaques in Alzheimer and Down pathologies. NeuroReport. 4:1993;69-72.
27. Weindel K., Marme D., Weich H.A. AIDS-associated Kaposi's sarcoma cells in culture express vascular endothelial growth factor. Biochem. Biophys. Res. Commun. 183:1992;1167-1174.