Down syndrome candidate region-1 protein interacts with Tollip and positively modulates interleukin-1 receptor-mediated signaling

Biochimica et Biophysica Acta - General Subjects

Volumn 1790, Issue 12, 2009, Pages 1673-1680

  Lee, Jae Youn ^a   Lee, Hyun Jung ^a   Lee, Eun Jung ^a   Jang, Sung Hee ^b,c   Kim, Hyeyoung ^a,b,d   Yoon, Joo Heon ^d   Chung, Kwang Chul ^a,d  

^a Yonsei University   (South Korea)

^b Department of Food and Nutrition ^*  (South Korea)

^c Research Institute of Food and Nutritional Sciences   (South Korea)

^d Yonsei University College of Medicine   (South Korea)

Author keywords

Cytokine; Down syndrome; Down Syndrome Critical Region; IL 1; Inflammation; Tollip

Indexed keywords

ADAPTOR PROTEIN; DOWN SYNDROME CANDIDATE REGION 1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 8; REGULATOR PROTEIN; TOLL INTERACTING PROTEIN; TOLLIP; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWNSTREAM PROCESSING; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSACTIVATION;

CELLS, CULTURED; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTERLEUKIN-8; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; MUSCLE PROTEINS; NF-KAPPA B; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN ISOFORMS; RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; UP-REGULATION;

EID: 71549158526     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2009.08.005     Document Type: Article

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