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Volumn 67, Issue 1, 2010, Pages 69-75

Molecular analysis of the HuD gene in neuroendocrine lung cancers

Author keywords

Carcinoid; ELAV like; HuD; Lung cancer; Mutation; Neuroendocrine tumor; SCLC

Indexed keywords

PROTEIN HUD; TUMOR PROTEIN; UNCLASSIFIED DRUG;

EID: 71549127741     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2009.03.022     Document Type: Article
Times cited : (24)

References (36)
  • 1
    • 0027309573 scopus 로고
    • Gene elav of Drosophila melanogaster: a prototype for neuronal-specific RNA binding protein gene family that is conserved in flies and humans
    • Yao K.M., Samson M.L., Reeves R., and White K. Gene elav of Drosophila melanogaster: a prototype for neuronal-specific RNA binding protein gene family that is conserved in flies and humans. J Neurobiol 24 (1993) 723-739
    • (1993) J Neurobiol , vol.24 , pp. 723-739
    • Yao, K.M.1    Samson, M.L.2    Reeves, R.3    White, K.4
  • 2
    • 0028158889 scopus 로고
    • Hu neuronal proteins are expressed in proliferating neurogenic cells
    • Marusich M.F., Furneaux H.M., Henion P.D., and Weston J.A. Hu neuronal proteins are expressed in proliferating neurogenic cells. J Neurobiol 25 2 (1994) 143-155
    • (1994) J Neurobiol , vol.25 , Issue.2 , pp. 143-155
    • Marusich, M.F.1    Furneaux, H.M.2    Henion, P.D.3    Weston, J.A.4
  • 3
    • 0030867877 scopus 로고    scopus 로고
    • Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression
    • Antic D., and Keene J.D. Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression. Am J Hum Genet 61 2 (1997) 273-278
    • (1997) Am J Hum Genet , vol.61 , Issue.2 , pp. 273-278
    • Antic, D.1    Keene, J.D.2
  • 4
    • 0026094583 scopus 로고
    • HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and sex-lethal
    • Szabo A., Dalmau J., Manley G., Rosenfeld M., Wong E., Henson J., Posner J.B., and Furneaux H.M. HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and sex-lethal. Cell 67 (1991) 325-333
    • (1991) Cell , vol.67 , pp. 325-333
    • Szabo, A.1    Dalmau, J.2    Manley, G.3    Rosenfeld, M.4    Wong, E.5    Henson, J.6    Posner, J.B.7    Furneaux, H.M.8
  • 5
    • 0028282129 scopus 로고
    • Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3′ UTR of mRNA encoding the Id transcriptional repressor
    • King P.H., Levine T.D., Fremeau R.T., and Keene J.D. Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3′ UTR of mRNA encoding the Id transcriptional repressor. J Neurosci 14 (1994) 1943-1952
    • (1994) J Neurosci , vol.14 , pp. 1943-1952
    • King, P.H.1    Levine, T.D.2    Fremeau, R.T.3    Keene, J.D.4
  • 7
    • 0029873536 scopus 로고    scopus 로고
    • Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein
    • Ma W.-J., Cheng S., Campbell C., Wright A., and Furneaux H. Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein. J Biol Chem 271 (1996) 8144-8151
    • (1996) J Biol Chem , vol.271 , pp. 8144-8151
    • Ma, W.-J.1    Cheng, S.2    Campbell, C.3    Wright, A.4    Furneaux, H.5
  • 8
    • 0030827809 scopus 로고    scopus 로고
    • Sequential expression and role of Hu RNA-binding proteins during neurogenesis
    • Wakamatsu Y., and Weston J.A. Sequential expression and role of Hu RNA-binding proteins during neurogenesis. Development 124 17 (1997) 3449-3460
    • (1997) Development , vol.124 , Issue.17 , pp. 3449-3460
    • Wakamatsu, Y.1    Weston, J.A.2
  • 9
    • 0029087998 scopus 로고
    • Hu protein as an early marker of neuronal phenotypic differentiation by subependymal zone cells of the adult songbird forebrain
    • Barami K., Iversen K., Furneaux H., and Goldman S. Hu protein as an early marker of neuronal phenotypic differentiation by subependymal zone cells of the adult songbird forebrain. J Neurobiol 28 (1995) 82-101
    • (1995) J Neurobiol , vol.28 , pp. 82-101
    • Barami, K.1    Iversen, K.2    Furneaux, H.3    Goldman, S.4
  • 10
    • 0027753933 scopus 로고
    • Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors
    • Birney E., Kumar S., and Krainer A.R. Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors. Nucleic Acids Res 21 (1993) 5803-5816
    • (1993) Nucleic Acids Res , vol.21 , pp. 5803-5816
    • Birney, E.1    Kumar, S.2    Krainer, A.R.3
  • 11
    • 0034046989 scopus 로고    scopus 로고
    • Hu immunolabeling as a marker of neural and neuroendocrine differentiation in normal and neoplastic human tissues: assessment using a recombinant anti-Hu Fab fragment
    • Gultekin S.H., Rosai J., Demopoulos A., Graus Y.F., Posner J.B., Dalmau J., and Rosemblum M.K. Hu immunolabeling as a marker of neural and neuroendocrine differentiation in normal and neoplastic human tissues: assessment using a recombinant anti-Hu Fab fragment. Int J Surg Pathol 8 2 (2000) 109-117
    • (2000) Int J Surg Pathol , vol.8 , Issue.2 , pp. 109-117
    • Gultekin, S.H.1    Rosai, J.2    Demopoulos, A.3    Graus, Y.F.4    Posner, J.B.5    Dalmau, J.6    Rosemblum, M.K.7
  • 12
    • 0029008249 scopus 로고
    • Hu antigens: reactivity with Hu antibodies, tumor expression, and major immunogenic sites
    • Manley G.T., Smitt P.S., Dalmau J., and Posner J.B. Hu antigens: reactivity with Hu antibodies, tumor expression, and major immunogenic sites. Ann Neurol 38 (1995) 102-110
    • (1995) Ann Neurol , vol.38 , pp. 102-110
    • Manley, G.T.1    Smitt, P.S.2    Dalmau, J.3    Posner, J.B.4
  • 13
    • 47749137063 scopus 로고    scopus 로고
    • Molecular detection of neuron-specific ELAV-like-positive cells in the peripheral blood of patients with small-cell lung cancer
    • D'Alessandro V., Muscarella L.A., Copetti M., Zelante L., Carella M., and Vendemiale G. Molecular detection of neuron-specific ELAV-like-positive cells in the peripheral blood of patients with small-cell lung cancer. Cell Oncol 30 (2008) 291-297
    • (2008) Cell Oncol , vol.30 , pp. 291-297
    • D'Alessandro, V.1    Muscarella, L.A.2    Copetti, M.3    Zelante, L.4    Carella, M.5    Vendemiale, G.6
  • 15
    • 0028136928 scopus 로고
    • Molecular analysis of the HuD gene encoding a paraneoplastic encephalomyelitis antigen in human lung cancer cell lines
    • Sekido Y., Bader S.A., Carbone D.P., Johnson B.E., and Minna J.D. Molecular analysis of the HuD gene encoding a paraneoplastic encephalomyelitis antigen in human lung cancer cell lines. Cancer Res 54 (1994) 4988-4992
    • (1994) Cancer Res , vol.54 , pp. 4988-4992
    • Sekido, Y.1    Bader, S.A.2    Carbone, D.P.3    Johnson, B.E.4    Minna, J.D.5
  • 17
    • 0033168843 scopus 로고    scopus 로고
    • Allelotype of posterior uveal melanoma: implications for a bifurcated tumor progression pathway
    • Parrella P., Sidransky D., and Merbs S.L. Allelotype of posterior uveal melanoma: implications for a bifurcated tumor progression pathway. Cancer Res 13 (1999) 3032-3037
    • (1999) Cancer Res , vol.13 , pp. 3032-3037
    • Parrella, P.1    Sidransky, D.2    Merbs, S.L.3
  • 19
    • 15844401767 scopus 로고    scopus 로고
    • Purification and properties of HuD, a neuronal RNA-binding protein
    • Chung S., Jiang L., Cheng S., and Furneaux H. Purification and properties of HuD, a neuronal RNA-binding protein. J Biol Chem 271 (1996) 11518-11524
    • (1996) J Biol Chem , vol.271 , pp. 11518-11524
    • Chung, S.1    Jiang, L.2    Cheng, S.3    Furneaux, H.4
  • 20
    • 0030821226 scopus 로고    scopus 로고
    • The Elav-like proteins bind to AU-rich elements and to the poly(A) tail of mRNA
    • Ma W.J., Chung S., and Furneaux H. The Elav-like proteins bind to AU-rich elements and to the poly(A) tail of mRNA. Nucleic Acids Res 25 (1997) 3564-3569
    • (1997) Nucleic Acids Res , vol.25 , pp. 3564-3569
    • Ma, W.J.1    Chung, S.2    Furneaux, H.3
  • 21
    • 0032526427 scopus 로고    scopus 로고
    • Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs
    • Fan X.C., and Steitz J.A. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J 17 (1998) 3448-3460
    • (1998) EMBO J , vol.17 , pp. 3448-3460
    • Fan, X.C.1    Steitz, J.A.2
  • 22
    • 0030459516 scopus 로고    scopus 로고
    • Two different RNA binding activities for the AU-rich element and the poly(A) sequence of the mouse neuronal protein mHuC
    • Abe R., Sakashita E., Yamamoto K., and Sakamoto H. Two different RNA binding activities for the AU-rich element and the poly(A) sequence of the mouse neuronal protein mHuC. Nucleic Acids Res 24 (1996) 4895-4901
    • (1996) Nucleic Acids Res , vol.24 , pp. 4895-4901
    • Abe, R.1    Sakashita, E.2    Yamamoto, K.3    Sakamoto, H.4
  • 23
    • 0035153840 scopus 로고    scopus 로고
    • Structural basis for recognition of AU-rich element RNA by the HuD protein
    • Wang X., and Tanaka Hall T.M. Structural basis for recognition of AU-rich element RNA by the HuD protein. Nat Struct Biol 8 (2001) 141-145
    • (2001) Nat Struct Biol , vol.8 , pp. 141-145
    • Wang, X.1    Tanaka Hall, T.M.2
  • 24
    • 33750353461 scopus 로고    scopus 로고
    • Predicting the effects of amino acid substitutions on protein function
    • Ng P.C., and Henikoff S. Predicting the effects of amino acid substitutions on protein function. Annu Rev Genomics Hum Genet 7 (2006) 61-80
    • (2006) Annu Rev Genomics Hum Genet , vol.7 , pp. 61-80
    • Ng, P.C.1    Henikoff, S.2
  • 25
    • 0034752993 scopus 로고    scopus 로고
    • Chromosomal aberrations in a series of large-cell neuroendocrine carcinomas: unexpected divergence from small-cell carcinoma of the lung
    • Ullmann R., Petzmann S., Sharma A., Cagle P.T., and Popper H.H. Chromosomal aberrations in a series of large-cell neuroendocrine carcinomas: unexpected divergence from small-cell carcinoma of the lung. Hum Pathol 32 (2001) 1059-1063
    • (2001) Hum Pathol , vol.32 , pp. 1059-1063
    • Ullmann, R.1    Petzmann, S.2    Sharma, A.3    Cagle, P.T.4    Popper, H.H.5
  • 26
    • 1542375346 scopus 로고    scopus 로고
    • Two prognostically significant subtypes of high-grade lung neuroendocrine tumours independent of small cell and large cell neuroendocrine carcinomas identified by gene expression profiles
    • Jones M.H., Virtanen C., Honjoh D., Miyoshi T., Satoh Y., Okumura S., et al. Two prognostically significant subtypes of high-grade lung neuroendocrine tumours independent of small cell and large cell neuroendocrine carcinomas identified by gene expression profiles. Lancet 363 (2004) 775-781
    • (2004) Lancet , vol.363 , pp. 775-781
    • Jones, M.H.1    Virtanen, C.2    Honjoh, D.3    Miyoshi, T.4    Satoh, Y.5    Okumura, S.6
  • 27
    • 0034098759 scopus 로고    scopus 로고
    • Gene product immunophenotyping of neuroendocrine lung tumors. No linking evidence between carcinoids and small-cell lung carcinomas suggested by multivariate statistical analysis
    • Sampietro G., Tomasic G., Collini P., Biganzoli E., Boracchi P., Bidoli P., et al. Gene product immunophenotyping of neuroendocrine lung tumors. No linking evidence between carcinoids and small-cell lung carcinomas suggested by multivariate statistical analysis. Appl Immunohistochem Mol Morphol 8 (2000) 49-56
    • (2000) Appl Immunohistochem Mol Morphol , vol.8 , pp. 49-56
    • Sampietro, G.1    Tomasic, G.2    Collini, P.3    Biganzoli, E.4    Boracchi, P.5    Bidoli, P.6
  • 28
    • 0032742820 scopus 로고    scopus 로고
    • Classification of small cell lung cancer and pulmonary carcinoid by gene expression profiles
    • Anbazhagan R., Tihan T., Bornman D.M., Tohnston J.C., Saltz J.H., Weigering A., et al. Classification of small cell lung cancer and pulmonary carcinoid by gene expression profiles. Cancer Res 59 (1999) 5119-5122
    • (1999) Cancer Res , vol.59 , pp. 5119-5122
    • Anbazhagan, R.1    Tihan, T.2    Bornman, D.M.3    Tohnston, J.C.4    Saltz, J.H.5    Weigering, A.6
  • 29
    • 0032148385 scopus 로고    scopus 로고
    • The human p19ARF protein encoded by the beta transcript of the p16INK4a gene is frequently lost in small cell lung cancer
    • Gazzeri S., Della Valle V., Chaussade L., Brambilla C., Larsen C.J., and Brambilla E. The human p19ARF protein encoded by the beta transcript of the p16INK4a gene is frequently lost in small cell lung cancer. Cancer Res 58 (1998) 3926-3931
    • (1998) Cancer Res , vol.58 , pp. 3926-3931
    • Gazzeri, S.1    Della Valle, V.2    Chaussade, L.3    Brambilla, C.4    Larsen, C.J.5    Brambilla, E.6
  • 30
    • 0029983299 scopus 로고    scopus 로고
    • Analysis of p53, K-ras-2, and C-raf-1 in pulmonary neuroendocrine tumors: correlation with histological subtype and clinical outcome
    • Przygodzki R.M., Finkelstein S.D., Langer J.C., Swalsky P.A., Fishback N., Bakker A., et al. Analysis of p53, K-ras-2, and C-raf-1 in pulmonary neuroendocrine tumors: correlation with histological subtype and clinical outcome. Am J Pathol 148 (1996) 1531-1541
    • (1996) Am J Pathol , vol.148 , pp. 1531-1541
    • Przygodzki, R.M.1    Finkelstein, S.D.2    Langer, J.C.3    Swalsky, P.A.4    Fishback, N.5    Bakker, A.6
  • 31
    • 0032530860 scopus 로고    scopus 로고
    • Molecular alterations to human chromosome 3p loci in neuroendocrine lung tumors
    • Kovatich A., Friedland D.M., Druck T., Hadaczek P., Huebner K., Comis R.L., et al. Molecular alterations to human chromosome 3p loci in neuroendocrine lung tumors. Cancer 83 (1998) 1109-1117
    • (1998) Cancer , vol.83 , pp. 1109-1117
    • Kovatich, A.1    Friedland, D.M.2    Druck, T.3    Hadaczek, P.4    Huebner, K.5    Comis, R.L.6
  • 32
    • 0031915739 scopus 로고    scopus 로고
    • Expression of bcl-2 in lung neuroendocrine tumours: comparison with p53
    • Wang D.-G., Johnston C.F., Sloan J.M., and Buchanan K.D. Expression of bcl-2 in lung neuroendocrine tumours: comparison with p53. J Pathol 184 (1998) 247-251
    • (1998) J Pathol , vol.184 , pp. 247-251
    • Wang, D.-G.1    Johnston, C.F.2    Sloan, J.M.3    Buchanan, K.D.4
  • 33
    • 0031017339 scopus 로고    scopus 로고
    • Differential retinoblastoma protein expression in neuroendocrine tumors of the lung: potential diagnostic implications
    • Cagle P.T., el-Naggar A.K., Xu H.J., Hu S.X., and Benedict W.F. Differential retinoblastoma protein expression in neuroendocrine tumors of the lung: potential diagnostic implications. Am J Pathol 150 (1997) 393-400
    • (1997) Am J Pathol , vol.150 , pp. 393-400
    • Cagle, P.T.1    el-Naggar, A.K.2    Xu, H.J.3    Hu, S.X.4    Benedict, W.F.5
  • 34
    • 0030880469 scopus 로고    scopus 로고
    • Differential expression of the neuroendocrine genes Hel-N1 and HuD in small-cell lung carcinoma: evidence for down-regulation of the HuD in the variant phenotype
    • King P.H. Differential expression of the neuroendocrine genes Hel-N1 and HuD in small-cell lung carcinoma: evidence for down-regulation of the HuD in the variant phenotype. Int J Cancer 74 (1997) 378-382
    • (1997) Int J Cancer , vol.74 , pp. 378-382
    • King, P.H.1
  • 35
    • 0035170498 scopus 로고    scopus 로고
    • Nicotinic receptor-mediated activation by tobacco-specific nitrosamine NNK of a Raf-1/MAP kinase pathway, resulting in phosphorylation of c-myc in human small cell lung carcinoma cells and pulmonary neuroendocrine cells
    • Jull B.A., Plummer III H.K., and Schuller H.M. Nicotinic receptor-mediated activation by tobacco-specific nitrosamine NNK of a Raf-1/MAP kinase pathway, resulting in phosphorylation of c-myc in human small cell lung carcinoma cells and pulmonary neuroendocrine cells. J Cancer Res Clin Oncol 127 (2001) 707-717
    • (2001) J Cancer Res Clin Oncol , vol.127 , pp. 707-717
    • Jull, B.A.1    Plummer III, H.K.2    Schuller, H.M.3
  • 36
    • 0034880685 scopus 로고    scopus 로고
    • Pulmonary carcinoid: presentation, diagnosis, and outcome in 142 cases in Israel and review of 640 cases from literature
    • Fink G., Krelbaum T., Yellin A., Bendayan D., Sante M., Glazer M., et al. Pulmonary carcinoid: presentation, diagnosis, and outcome in 142 cases in Israel and review of 640 cases from literature. Chest 119 (2001) 1647-1651
    • (2001) Chest , vol.119 , pp. 1647-1651
    • Fink, G.1    Krelbaum, T.2    Yellin, A.3    Bendayan, D.4    Sante, M.5    Glazer, M.6


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