Chromosomal aberrations in a series of large-cell neuroendocrine carcinomas: Unexpected divergence from small-cell carcinoma of the lung

Human Pathology

Volumn 32, Issue 10, 2001, Pages 1059-1063

  Ullmann, Reinhard ^a,b   Petzmann, Susanna ^a,b   Sharma, Anu ^a,b   Cagle, Philip Theo ^a,b   Popper, Helmut Hans ^a,b  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Comparative genomic hybridization; Large cell neuroendocrine carcinoma; Small cell lung cancer

Indexed keywords

ARTICLE; CANCER GRADING; CHROMOSOME 10Q; CHROMOSOME 13Q; CHROMOSOME 3Q; CHROMOSOME 4Q; CHROMOSOME 5Q; CHROMOSOME ABERRATION; CHROMOSOME DELETION; CHROMOSOME LOSS; COMPARATIVE GENOMIC HYBRIDIZATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; LUNG SMALL CELL CANCER; NEUROENDOCRINE TUMOR; ONCOGENE;

EID: 0034752993     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1053/hupa.2001.28248     Document Type: Article

References (13)

1. Genetic changes in the spectrum of neuroendocrine lung tumors
2. Analysis of p53, K-ras-2, and C-raf-1 in pulmonary neuroendocrine tumors. Correlation with histological subtype and clinical outcome
3. Typical and atypical carcinoid tumors of the lung are characterized by 11q deletions as detected by comparative genomic hybridization
4. Comparison of chromosomal imbalances in neuroendocrine and non-small-cell lung carcinomas
5. Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors
6. Identification of novel regions of altered DNA copy number in small cell lung tumors
7. Small-cell lung cancer is characterized by a high incidence of deletions on chromosomes 3p, 4q, 5q, 10q, 13q and 17p
8. Unbalanced chromosomal aberrations in neuroendocrine lung tumors as detected by comparative genomic hybridization
9. Patterns of chromosomal imbalances in adenocarcinoma and squamous cell carcinoma of the lung
10. Chromosomal imbalance maps of malignant solid tumors: A cytogenetic survey of 3185 neoplasms
11. Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix
12. Distinct regions of allelic imbalance on chromosome 10q22-q26 in squamous cell carcinomas of the lung
13. Cellular senescence and cancer