Short-term vitamin A supplementation at therapeutic doses induces a pro-oxidative state in the hepatic environment and facilitates calcium-ion-induced oxidative stress in rat liver mitochondria independently from permeability transition pore formation: Detrimental effects of vitamin A supplementation on rat liver redox and bioenergetic states homeostasis

Cell Biology and Toxicology

Volumn 25, Issue 6, 2009, Pages 545-560

  De Oliveira, Marcos Roberto ^a   Oliveira, Max William Soares ^a   Lorenzi, Rodrigo ^a   Fagundes Da Rocha, Ricardo ^a   Fonseca Moreira, José Cláudio ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Calcium ions; Mitochondria; Oxidative stress; Rat liver; Vitamin A

Indexed keywords

CATALASE; CYCLOSPORIN A; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; RETINOL PALMITATE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON TRANSPORT; ENZYME ACTIVITY; LIPID PEROXIDATION; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION SWELLING; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CARBONYLATION; RAT; SUBMITOCHONDRIAL PARTICLE; VITAMIN SUPPLEMENTATION;

ANIMALS; CALCIUM; CYCLOSPORINE; ELECTRON TRANSPORT; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYME INHIBITORS; HOMEOSTASIS; LIVER; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; OXIDATION-REDUCTION; OXIDATIVE STRESS; OXIDOREDUCTASES; RATS; SUBMITOCHONDRIAL PARTICLES; SUPEROXIDES; VITAMIN A;

RATTUS;

EID: 71349086815     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10565-008-9111-9     Document Type: Article

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