IkBα promoter polymorphisms in patients with ankylosing spondylitis

Rheumatology International

Volumn 30, Issue 1, 2009, Pages 93-97

  Hung, Yu Hung ^a   Ou, Tsan Teng ^b   Lin, Chia Hui ^b   Li, Ruei Nian ^c   Lin, Yu Chih ^b   Tsai, Wen Chan ^b   Liu, Hong Wen ^b   Yen, Jeng Hsien ^a,b,c  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Ankylosing spondylitis; I B ; NF B inhibitor; Polymorphism

Indexed keywords

I KAPPA B ALPHA;

ADULT; ANKYLOSING SPONDYLITIS; ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; TAIWAN;

ADULT; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; I-KAPPA B PROTEINS; MALE; MIDDLE AGED; ODDS RATIO; PHENOTYPE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; RISK ASSESSMENT; RISK FACTORS; SPONDYLITIS, ANKYLOSING; TAIWAN;

EID: 71349084427     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00296-009-0923-6     Document Type: Article

References (34)

1. J Braun J Sieper 2007 Ankylosing spondylitis Lancet 369 1379 1390 10.1016/S0140-6736(07)60635-7 10.1016/S0140-6736(07)60635-7 17448825 (Pubitemid 46590387)
2. MA Brown LG Kennedy AJ MacGregor C Darke E Duncan JL Shatford A Taylor A Calin P Wordsworth 1997 Susceptibility to ankylosing spondylitis in twins: the role of genes, HLA, and the environment Arthritis Rheum 40 1823 1828 10.1002/art.1780401015 10.1002/art.1780401015 1:STN:280:DyaK2svns1WltA%3D%3D 9336417 (Pubitemid 27452533)
3. SM van der Linden HA Valkenburg BM de Jongh A Cats 1984 The risk of developing ankylosing spondylitis in HLA-B27 positive individuals. A comparison of relatives of spondylitis patients with the general population Arthritis Rheum 27 241 249 10.1002/art.1780270301 10.1002/art.1780270301 6608352 (Pubitemid 14163215)
4. MA Brown 2006 Non-major-histocompatibility-complex genetics of ankylosing spondylitis Best Pract Res Clin Rheumatol 20 611 621 10.1016/j.berh.2006.03.005 10.1016/j.berh.2006.03.005 1:CAS:528:DC%2BD28Xls1aqu70%3D 16777586 (Pubitemid 43843067)
5. MA Brown 2007 Breakthroughs in genetic studies of ankylosing spondylitis Rheumatology (Oxford) 47 132 137 10.1093/rheumatology/kem269
6. PR Burton DG Clayton LR Cardon N Craddock P Deloukas A Duncanson DP Kwiatkowski MI McCarthy WH Ouwehand NJ Samani, et al. 2007 Association Scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants Nat Genet 39 1329 1337 10.1038/ng.2007.17 10.1038/ng.2007.17 1:CAS:528: DC%2BD2sXht1aqtrvF 17952073 (Pubitemid 350041542)
7. KW Carter A Pluzhnikov AE Timms C Miceli-Richard C Bourgain BP Wordsworth H Jean-Pierre NJ Cox LJ Palmer M Breban, et al. 2007 Combined analysis of three whole genome linkage scans for ankylosing spondylitis Rheumatology (Oxford) 46 763 771 10.1093/rheumatology/kel443 10.1093/rheumatology/kel443 1:STN:280:DC%2BD2s3jvVCqug%3D%3D (Pubitemid 47061705)
8. SH Laval A Timms S Edwards L Bradbury S Brophy A Milicic L Rubin KA Siminovitch DE Weeks A Calin, et al. 2001 Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci Am J Hum Genet 68 918 926 10.1086/319509 10.1086/319509 1:CAS:528:DC%2BD3MXkvFars7o%3D 11231900 (Pubitemid 32289738)
9. JH Yen WC Tsai CJ Chen CH Lin TT Ou CJ Hu HW Liu 2003 Cytochrome P450 1a1 and manganese superoxide dismutase genes polymorphisms in ankylosing spondylitis Immunol Lett 88 113 116 10.1016/S0165-2478(03)00071-3 10.1016/S0165-2478(03)00071-3 1:CAS:528:DC%2BD3sXls1Ogtbs%3D 12880680 (Pubitemid 36859974)
10. PJ Barnes M Karin 1997 Nuclear factor-kappa B: a pivotal transcription factor in chronic inflammatory diseases N Engl J Med 336 1066 1071 10.1056/NEJM199704103361506 10.1056/NEJM199704103361506 1:CAS:528: DyaK2sXis1SrsLw%3D 9091804 (Pubitemid 27163860)
11. PA Baeuerle 1998 Pro-inflammatory signaling: last pieces in the NF-Kappa B puzzle? Curr Biol 8 R19 R22 10.1016/S0960-9822(98)70010-7 10.1016/S0960- 9822(98)70010-7 1:STN:280:DyaK1c%2FovFWltw%3D%3D 9427616
12. PP Tak GS Firestein 2001 NF-KappaB: a key role in inflammatory diseases J Clin Invest 107 7 11 10.1172/JCI11830 10.1172/JCI11830 1:CAS:528: DC%2BD3MXitVOhtg%3D%3D 11134171
13. S Castro-Alcaraz V Miskolci B Kalasapudi D Davidson I Vancurova 2002 NF-Kappa B regulation in human neutrophils by nuclear I Kappa B alpha: correlation to apoptosis J Immunol 169 3947 3953 1:CAS:528:DC%2BD38XnsFeltbY%3D 12244195
14. IK Campbell S Gerondakis K O'Donnell IP Wicks 2000 Distinct roles for the NF-Kappa B1 (P50) and C-Rel transcription factors in inflammatory arthritis J Clin Invest 105 1799 1806 10.1172/JCI8298 10.1172/JCI8298 1:CAS:528: DC%2BD3cXkt1WqsLg%3D 10862795
15. MJ May S Ghosh 1997 Rel/NF-Kappa B and I Kappa B proteins: an overview Semin Cancer Biol 8 63 73 10.1006/scbi.1997.0057 10.1006/scbi.1997.0057 1:CAS:528:DyaK2sXmtlGqsbw%3D 9299584 (Pubitemid 27412322)
16. ST Whiteside A Israel 1997 I Kappa B proteins: structure, function and regulation Semin Cancer Biol 8 75 82 10.1006/scbi.1997.0058 10.1006/scbi.1997. 0058 1:CAS:528:DyaK2sXmtlGqsb0%3D 9299585 (Pubitemid 27412323)
17. N Mozzato-Chamay EL Corbett RL Bailey DC Mabey J Raynes DJ Conway 2001 Polymorphisms in the I kappa B-alpha promoter region and risk of diseases involving inflammation and fibrosis Genes Immun 2 153 155 10.1038/sj.gene. 6363753 10.1038/sj.gene.6363753 1:CAS:528:DC%2BD3MXksVyitr4%3D 11426324 (Pubitemid 33674880)
18. CY Ito AG Kazantsev AS Baldwin Jr 1994 Three NF-Kappa B sites in the I Kappa B-alpha promoter are required for induction of gene expression by TNF alpha Nucleic Acids Res 22 3787 3792 10.1093/nar/22.18.3787 10.1093/nar/22.18. 3787 1:CAS:528:DyaK2MXhtlOmsLc%3D 7937093
19. CH Lin TT Ou CC Wu WC Tsai HW Liu JH Yen 2007 I Kappa B alpha promoter polymorphisms in patients with rheumatoid arthritis Int J Immunogenet 34 51 54 10.1111/j.1744-313X.2007.00660.x 10.1111/j.1744-313X.2007.00660.x 1:CAS:528:DC%2BD2sXitlymu7Y%3D 17284228 (Pubitemid 46232342)
20. CH Lin SC Wang TT Ou RN Li WC Tsai HW Liu JH Yen 2008 I Kappa B alpha promoter polymorphisms in patients with systemic lupus erythematosus J Clin Immunol 28 207 213 10.1007/s10875-007-9156-1 10.1007/s10875-007-9156-1 1:CAS:528:DC%2BD1cXltFOqtL8%3D 18071880
21. TT Ou CH Lin YC Lin RN Li WC Tsai HW Liu JH Yen 2008 I Kappa B alpha promoter polymorphisms in patients with primary Sjogren's Syndrome J Clin Immunol 28 440 444 10.1007/s10875-008-9212-5 10.1007/s10875-008-9212-5 1:CAS:528:DC%2BD1cXhtVyjt7bP 18600435
22. F Arenzana-Seisdedos J Thompson MS Rodriguez F Bachelerie D Thomas RT Hay 1995 Inducible nuclear expression of newly synthesized I Kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-Kappa B Mol Cell Biol 15 2689 2696 1:STN:280:DyaK2M3lsl2msg%3D%3D 7739549
23. P Turpin RT Hay C Dargemont 1999 Characterization of I Kappa B alpha nuclear import pathway J Biol Chem 274 6804 6812 10.1074/jbc.274.10.6804 10.1074/jbc.274.10.6804 1:CAS:528:DyaK1MXhs1eqs7w%3D 10037782 (Pubitemid 29111105)
24. F Arenzana-Seisdedos P Turpin M Rodriguez D Thomas RT Hay JL Virelizier C Dargemont 1997 Nuclear localization of I Kappa B alpha promotes active transport of NF-Kappa B from the nucleus to the cytoplasm J Cell Sci 110 Pt 3 369 378 1:CAS:528:DyaK2sXhsFams7Y%3D 9057089
25. MK Ernst LL Dunn NR Rice 1995 The pest-like sequence of I Kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of C-Rel or Rela homodimers Mol Cell Biol 15 872 882 1:CAS:528: DyaK2MXjtlantrg%3D 7823953
26. B Miterski S Bohringer W Klein E Sindern M Haupts S Schimrigk JT Epplen 2002 Inhibitors in the NF kappa B cascade comprise prime candidate genes predisposing to multiple sclerosis, especially in selected combinations Genes Immun 3 211 219 10.1038/sj.gene.6363846 10.1038/sj.gene.6363846 1:CAS:528:DC%2BD38XksFCisrg%3D 12058256 (Pubitemid 38961133)
27. W Klein A Tromm C Folwaczny M Hagedorn N Duerig JT Epplen WH Schmiegel T Griga 2004 A polymorphism of the NFKB IA gene is associated with Crohn's Disease patients lacking a predisposing allele of the card15 gene Int J Colorectal Dis 19 153 156 10.1007/s00384-003-0531-y 10.1007/s00384-003-0531-y 13680285 (Pubitemid 38239837)
28. J Gao D Pfeifer LJ He F Qiao Z Zhang G Arbman ZL Wang CR Jia J Carstensen XF Sun 2007 Association of NFKBIA polymorphism with colorectal cancer risk and prognosis in Swedish and Chinese populations Scand J Gastroenterol 42 345 350 10.1080/00365520600880856 10.1080/00365520600880856 1:CAS:528: DC%2BD2sXkt12ntLs%3D 17354114 (Pubitemid 46303833)
29. XF Sun H Zhang 2007 Nfkb and Nfkbi polymorphisms in relation to susceptibility of tumour and other diseases Histol Histopathol 22 1387 1398 1:CAS:528:DC%2BD2sXhtlaksL7I 17701919
30. A Abdallah H Sato JC Grutters S Veeraraghavan PA Lympany HJ Ruven JM van den Bosch AU Wells RM du Bois KI Welsh 2003 Inhibitor Kappa B-Alpha (I Kappa B-alpha) promoter polymorphisms in UK and Dutch sarcoidosis Genes Immun 4 450 454 10.1038/sj.gene.6364001 10.1038/sj.gene.6364001 1:CAS:528: DC%2BD3sXms12qu7Y%3D 12944982 (Pubitemid 38967610)
31. F Emmerich M Meiser M Hummel G Demel HD Foss F Jundt S Mathas D Krappmann C Scheidereit H Stein, et al. 1999 Overexpression of I Kappa B alpha without inhibition of NF-Kappa B activity and mutations in the I Kappa B alpha gene in Reed-Sternberg cells Blood 94 3129 3134 1:CAS:528:DyaK1MXntVSrt7w%3D 10556199
32. E Cabannes G Khan F Aillet RF Jarrett RT Hay 1999 Mutations in the IKBA gene in Hodgkin's Disease suggest a tumour suppressor role for I Kappa B alpha Oncogene 18 3063 3070 10.1038/sj.onc.1202893 10.1038/sj.onc.1202893 1:CAS:528:DyaK1MXjs1OntbY%3D 10340377 (Pubitemid 29261226)
33. AA Beg WC Sha RT Bronson D Baltimore 1995 Constitutive NF-Kappa B activation, enhanced granulopoiesis, and neonatal lethality in I Kappa B alpha-deficient mice Genes Dev 9 2736 2746 10.1101/gad.9.22.2736 10.1101/gad.9.22.2736 1:CAS:528:DyaK2MXpslOmsbo%3D 7590249
34. JF Klement NR Rice BD Car SJ Abbondanzo GD Powers PH Bhatt CH Chen CA Rosen CL Stewart 1996 I Kappa B alpha deficiency results in a sustained NF-Kappa B response and severe widespread dermatitis in mice Mol Cell Biol 16 2341 2349 1:CAS:528:DyaK28XisFekt7w%3D 8628301