메뉴 건너뛰기




Volumn 52, Issue 1, 2010, Pages 16-24

Hepatic lipid profiling in chronic hepatitis C: An in vitro and in vivo proton magnetic resonance spectroscopy study

Author keywords

Lipid; Liver; Metabolic; MR spectroscopy; Non invasive; Steatosis

Indexed keywords

CHOLESTEROL; POLYUNSATURATED FATTY ACID; TRIACYLGLYCEROL;

EID: 71249105685     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2009.10.006     Document Type: Article
Times cited : (37)

References (44)
  • 1
    • 0034987263 scopus 로고    scopus 로고
    • Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity
    • Adinolfi L.E., Gambardella M., Andreana A., Tripodi M.F., Utili R., and Ruggiero G. Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity. Hepatology 33 (2001) 1358-1364
    • (2001) Hepatology , vol.33 , pp. 1358-1364
    • Adinolfi, L.E.1    Gambardella, M.2    Andreana, A.3    Tripodi, M.F.4    Utili, R.5    Ruggiero, G.6
  • 2
    • 10744224920 scopus 로고    scopus 로고
    • Steatosis affects chronic hepatitis C progression in a genotype specific way
    • Rubbia-Brandt L., Fabris P., Paganin S., Leandro G., Male P.J., Giostra E., et al. Steatosis affects chronic hepatitis C progression in a genotype specific way. Gut 53 (2004) 406-412
    • (2004) Gut , vol.53 , pp. 406-412
    • Rubbia-Brandt, L.1    Fabris, P.2    Paganin, S.3    Leandro, G.4    Male, P.J.5    Giostra, E.6
  • 3
    • 37649012154 scopus 로고    scopus 로고
    • Hepatic steatosis in chronic hepatitis C: baseline host and viral characteristics and influence on response to therapy with peginterferon alpha-2a plus ribavirin
    • Reddy K.R., Govindarajan S., Marcellin P., Bernstein D., Dienstag J.L., Bodenheimer Jr. H., et al. Hepatic steatosis in chronic hepatitis C: baseline host and viral characteristics and influence on response to therapy with peginterferon alpha-2a plus ribavirin. J Viral Hepat 15 (2008) 129-136
    • (2008) J Viral Hepat , vol.15 , pp. 129-136
    • Reddy, K.R.1    Govindarajan, S.2    Marcellin, P.3    Bernstein, D.4    Dienstag, J.L.5    Bodenheimer Jr., H.6
  • 4
    • 0033933140 scopus 로고    scopus 로고
    • Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3
    • Rubbia-Brandt L., Quadri R., Abid K., Giostra E., Male P.J., Mentha G., et al. Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3. J Hepatol 33 (2000) 106-115
    • (2000) J Hepatol , vol.33 , pp. 106-115
    • Rubbia-Brandt, L.1    Quadri, R.2    Abid, K.3    Giostra, E.4    Male, P.J.5    Mentha, G.6
  • 5
    • 34548130208 scopus 로고    scopus 로고
    • The genotype 3-specific hepatitis C virus core protein residue phenylalanine 164 increases steatosis in an in vitro cellular model
    • Hourioux C., Patient R., Morin A., Blanchard E., Moreau A., Trassard S., et al. The genotype 3-specific hepatitis C virus core protein residue phenylalanine 164 increases steatosis in an in vitro cellular model. Gut 56 (2007) 1302-1308
    • (2007) Gut , vol.56 , pp. 1302-1308
    • Hourioux, C.1    Patient, R.2    Morin, A.3    Blanchard, E.4    Moreau, A.5    Trassard, S.6
  • 6
    • 0345655291 scopus 로고    scopus 로고
    • Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression [corrected]
    • Hui J.M., Sud A., Farrell G.C., Bandara P., Byth K., Kench J.G., et al. Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression [corrected]. Gastroenterology 125 (2003) 1695-1704
    • (2003) Gastroenterology , vol.125 , pp. 1695-1704
    • Hui, J.M.1    Sud, A.2    Farrell, G.C.3    Bandara, P.4    Byth, K.5    Kench, J.G.6
  • 7
    • 33644806684 scopus 로고    scopus 로고
    • Insulin resistance is associated with steatosis in nondiabetic patients with genotype 1 chronic hepatitis C
    • Camma C., Bruno S., Di Macro V., Di Bona D., Rumi M., Vinci M., et al. Insulin resistance is associated with steatosis in nondiabetic patients with genotype 1 chronic hepatitis C. Hepatology 43 (2006) 64-71
    • (2006) Hepatology , vol.43 , pp. 64-71
    • Camma, C.1    Bruno, S.2    Di Macro, V.3    Di Bona, D.4    Rumi, M.5    Vinci, M.6
  • 8
    • 29244484291 scopus 로고    scopus 로고
    • Steatosis in chronic hepatitis C: why does it really matter?
    • Asselah T., Rubbia-Brandt L., Marcellin P., and Negro F. Steatosis in chronic hepatitis C: why does it really matter?. Gut 55 (2006) 123-130
    • (2006) Gut , vol.55 , pp. 123-130
    • Asselah, T.1    Rubbia-Brandt, L.2    Marcellin, P.3    Negro, F.4
  • 9
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleiner D.E., Brunt E.M., Van Natta M., Behling C., Contos M.J., Cummings O.W., et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 41 (2005) 1313-1321
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3    Behling, C.4    Contos, M.J.5    Cummings, O.W.6
  • 11
    • 0029778988 scopus 로고    scopus 로고
    • An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group
    • Bedossa P., and Poynard T. An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. Hepatology 24 (1996) 289-293
    • (1996) Hepatology , vol.24 , pp. 289-293
    • Bedossa, P.1    Poynard, T.2
  • 12
    • 12144259379 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population
    • Szczepaniak L.S., Nurenberg P., Leonard D., Browning J.D., Reingold J.S., Grundy S., et al. Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population. Am J Physiol Endocrinol Metab 288 (2005) E462-E468
    • (2005) Am J Physiol Endocrinol Metab , vol.288
    • Szczepaniak, L.S.1    Nurenberg, P.2    Leonard, D.3    Browning, J.D.4    Reingold, J.S.5    Grundy, S.6
  • 13
    • 10844240700 scopus 로고    scopus 로고
    • Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study
    • Thomas E.L., Hamilton G., Patel N., O'Dwyer R., Dore C.J., Goldin R.D., et al. Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study. Gut 54 (2005) 122-127
    • (2005) Gut , vol.54 , pp. 122-127
    • Thomas, E.L.1    Hamilton, G.2    Patel, N.3    O'Dwyer, R.4    Dore, C.J.5    Goldin, R.D.6
  • 14
    • 0037382071 scopus 로고    scopus 로고
    • Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis
    • Musso G., Gambino R., De Michieli F., Cassader M., Rizzetto M., Durazzo M., et al. Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis. Hepatology 37 (2003) 909-916
    • (2003) Hepatology , vol.37 , pp. 909-916
    • Musso, G.1    Gambino, R.2    De Michieli, F.3    Cassader, M.4    Rizzetto, M.5    Durazzo, M.6
  • 15
    • 30944451788 scopus 로고    scopus 로고
    • Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis
    • Wang D., Wei Y., and Pagliassotti M.J. Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis. Endocrinology 147 (2006) 943-951
    • (2006) Endocrinology , vol.147 , pp. 943-951
    • Wang, D.1    Wei, Y.2    Pagliassotti, M.J.3
  • 17
    • 63449098721 scopus 로고    scopus 로고
    • Phenotyping murine models of non-alcoholic fatty liver disease through metabolic profiling of intact liver tissue
    • Cobbold J.F., Anstee Q.M., Goldin R.D., Williams H.R., Matthews H.C., North B.V., et al. Phenotyping murine models of non-alcoholic fatty liver disease through metabolic profiling of intact liver tissue. Clin Sci (Lond) 116 5 (2009) 403-413
    • (2009) Clin Sci (Lond) , vol.116 , Issue.5 , pp. 403-413
    • Cobbold, J.F.1    Anstee, Q.M.2    Goldin, R.D.3    Williams, H.R.4    Matthews, H.C.5    North, B.V.6
  • 18
    • 0030198302 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid deficiency in liver diseases: pathophysiological and clinical significance
    • Cabre E., and Gassull M.A. Polyunsaturated fatty acid deficiency in liver diseases: pathophysiological and clinical significance. Nutrition 12 (1996) 542-548
    • (1996) Nutrition , vol.12 , pp. 542-548
    • Cabre, E.1    Gassull, M.A.2
  • 19
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleiner D.E., Brunt E.M., Van N.M., Behling C., Contos M.J., Cummings O.W., et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 41 (2005) 1313-1321
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van, N.M.3    Behling, C.4    Contos, M.J.5    Cummings, O.W.6
  • 20
    • 32844455119 scopus 로고    scopus 로고
    • Metabolite identification in human liver needle biopsies by high-resolution magic angle spinning 1H NMR spectroscopy
    • Martinez-Granados B., Monleon D., Martinez-Bisbal M.C., Rodrigo J.M., del Olmo J., Lluch P., et al. Metabolite identification in human liver needle biopsies by high-resolution magic angle spinning 1H NMR spectroscopy. NMR Biomed 19 (2006) 90-100
    • (2006) NMR Biomed , vol.19 , pp. 90-100
    • Martinez-Granados, B.1    Monleon, D.2    Martinez-Bisbal, M.C.3    Rodrigo, J.M.4    del Olmo, J.5    Lluch, P.6
  • 21
    • 0033859467 scopus 로고    scopus 로고
    • High-resolution (1)H and (1)H-(13)C magic angle spinning NMR spectroscopy of rat liver
    • Bollard M.E., Garrod S., Holmes E., Lindon J.C., Humpfer E., Spraul M., et al. High-resolution (1)H and (1)H-(13)C magic angle spinning NMR spectroscopy of rat liver. Magn Reson Med 44 (2000) 201-207
    • (2000) Magn Reson Med , vol.44 , pp. 201-207
    • Bollard, M.E.1    Garrod, S.2    Holmes, E.3    Lindon, J.C.4    Humpfer, E.5    Spraul, M.6
  • 22
    • 24644501162 scopus 로고    scopus 로고
    • Metabolic assessment of human liver transplants from biopsy samples at the donor and recipient stages using high-resolution magic angle spinning 1H NMR spectroscopy
    • Duarte I.F., Stanley E.G., Holmes E., Lindon J.C., Gil A.M., Tang H., et al. Metabolic assessment of human liver transplants from biopsy samples at the donor and recipient stages using high-resolution magic angle spinning 1H NMR spectroscopy. Anal Chem 77 (2005) 5570-5578
    • (2005) Anal Chem , vol.77 , pp. 5570-5578
    • Duarte, I.F.1    Stanley, E.G.2    Holmes, E.3    Lindon, J.C.4    Gil, A.M.5    Tang, H.6
  • 23
    • 0242290993 scopus 로고    scopus 로고
    • High-resolution diffusion and relaxation-edited magic angle spinning 1H NMR spectroscopy of intact liver tissue
    • Rooney O.M., Troke J., Nicholson J.K., and Griffin J.L. High-resolution diffusion and relaxation-edited magic angle spinning 1H NMR spectroscopy of intact liver tissue. Magn Reson Med 50 (2003) 925-930
    • (2003) Magn Reson Med , vol.50 , pp. 925-930
    • Rooney, O.M.1    Troke, J.2    Nicholson, J.K.3    Griffin, J.L.4
  • 24
    • 0034989141 scopus 로고    scopus 로고
    • Java-based graphical user interface for the MRUI quantitation package
    • Naressi A., Couturier C., Devos J.M., Janssen M., Mangeat C., de Beer R., et al. Java-based graphical user interface for the MRUI quantitation package. MAGMA 12 (2001) 141-152
    • (2001) MAGMA , vol.12 , pp. 141-152
    • Naressi, A.1    Couturier, C.2    Devos, J.M.3    Janssen, M.4    Mangeat, C.5    de Beer, R.6
  • 25
    • 0346308381 scopus 로고    scopus 로고
    • Improved method for accurate and efficient quantification of MRS data with use of prior knowledge
    • Vanhamme L., van den B.A., and Van Huffel S. Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J Magn Reson 129 (1997) 35-43
    • (1997) J Magn Reson , vol.129 , pp. 35-43
    • Vanhamme, L.1    van den, B.A.2    Van Huffel, S.3
  • 26
    • 0042129985 scopus 로고    scopus 로고
    • Prior knowledge for time domain quantification of in vivo brain or liver 31P MR spectra
    • Hamilton G., Patel N., Forton D.M., Hajnal J.V., and Taylor-Robinson S.D. Prior knowledge for time domain quantification of in vivo brain or liver 31P MR spectra. NMR Biomed 16 (2003) 168-176
    • (2003) NMR Biomed , vol.16 , pp. 168-176
    • Hamilton, G.1    Patel, N.2    Forton, D.M.3    Hajnal, J.V.4    Taylor-Robinson, S.D.5
  • 27
    • 43949144276 scopus 로고    scopus 로고
    • Noninvasive assessment of hepatic lipid composition: advancing understanding and management of fatty liver disorders
    • Johnson N.A., Walton D.W., Sachinwalla T., Thompson C.H., Smith K., Ruell P.A., et al. Noninvasive assessment of hepatic lipid composition: advancing understanding and management of fatty liver disorders. Hepatology 47 (2008) 1513-1523
    • (2008) Hepatology , vol.47 , pp. 1513-1523
    • Johnson, N.A.1    Walton, D.W.2    Sachinwalla, T.3    Thompson, C.H.4    Smith, K.5    Ruell, P.A.6
  • 28
    • 0029300637 scopus 로고
    • Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis
    • Longo R., Pollesello P., Ricci C., Masutti F., Kvam B.J., Bercich L., et al. Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis. J Magn Reson Imaging 5 (1995) 281-285
    • (1995) J Magn Reson Imaging , vol.5 , pp. 281-285
    • Longo, R.1    Pollesello, P.2    Ricci, C.3    Masutti, F.4    Kvam, B.J.5    Bercich, L.6
  • 29
    • 0035186270 scopus 로고    scopus 로고
    • Chronic hepatitis: in vivo proton MR spectroscopic evaluation of the liver and correlation with histopathologic findings
    • Cho S.G., Kim M.Y., Kim H.J., Kim Y.S., Choi W., Shin S.H., et al. Chronic hepatitis: in vivo proton MR spectroscopic evaluation of the liver and correlation with histopathologic findings. Radiology 221 (2001) 740-746
    • (2001) Radiology , vol.221 , pp. 740-746
    • Cho, S.G.1    Kim, M.Y.2    Kim, H.J.3    Kim, Y.S.4    Choi, W.5    Shin, S.H.6
  • 31
    • 0037208214 scopus 로고    scopus 로고
    • H MR spectroscopy in the evaluation of the severity of chronic liver disease
    • Lim A.K., Hamilton G., Patel N., Bell J.D., and Taylor-Robinson S.D. H MR spectroscopy in the evaluation of the severity of chronic liver disease. Radiology 226 (2003) 288-289
    • (2003) Radiology , vol.226 , pp. 288-289
    • Lim, A.K.1    Hamilton, G.2    Patel, N.3    Bell, J.D.4    Taylor-Robinson, S.D.5
  • 32
    • 51349093063 scopus 로고    scopus 로고
    • In vitro proton magnetic resonance spectroscopy of liver tissue informs in vivo hepatic proton magnetic resonance spectroscopy studies
    • Cobbold J.F., Taylor-Robinson S.D., and Cox I.J. In vitro proton magnetic resonance spectroscopy of liver tissue informs in vivo hepatic proton magnetic resonance spectroscopy studies. Hepatology 48 (2008) 1016-1017
    • (2008) Hepatology , vol.48 , pp. 1016-1017
    • Cobbold, J.F.1    Taylor-Robinson, S.D.2    Cox, I.J.3
  • 33
    • 18244365866 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis
    • Perlemuter G., Sabile A., Letteron P., Vona G., Topilco A., Chretien Y., et al. Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis. FASEB J 16 (2002) 185-194
    • (2002) FASEB J , vol.16 , pp. 185-194
    • Perlemuter, G.1    Sabile, A.2    Letteron, P.3    Vona, G.4    Topilco, A.5    Chretien, Y.6
  • 34
    • 34547097746 scopus 로고    scopus 로고
    • Hepatitis C virus induces proteolytic cleavage of sterol regulatory element binding proteins and stimulates their phosphorylation via oxidative stress
    • Waris G., Felmlee D.J., Negro F., and Siddiqui A. Hepatitis C virus induces proteolytic cleavage of sterol regulatory element binding proteins and stimulates their phosphorylation via oxidative stress. J Virol 81 (2007) 8122-8130
    • (2007) J Virol , vol.81 , pp. 8122-8130
    • Waris, G.1    Felmlee, D.J.2    Negro, F.3    Siddiqui, A.4
  • 35
    • 1542287381 scopus 로고    scopus 로고
    • Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance
    • Shintani Y., Fujie H., Miyoshi H., Tsutsumi T., Tsukamoto K., Kimura S., et al. Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance. Gastroenterology 126 (2004) 840-848
    • (2004) Gastroenterology , vol.126 , pp. 840-848
    • Shintani, Y.1    Fujie, H.2    Miyoshi, H.3    Tsutsumi, T.4    Tsukamoto, K.5    Kimura, S.6
  • 37
    • 0023833533 scopus 로고
    • The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes
    • Yao Z.M., and Vance D.E. The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes. J Biol Chem 263 (1988) 2998-3004
    • (1988) J Biol Chem , vol.263 , pp. 2998-3004
    • Yao, Z.M.1    Vance, D.E.2
  • 38
    • 0036829872 scopus 로고    scopus 로고
    • An unexpected requirement for phosphatidylethanolamine N-methyltransferase in the secretion of very low density lipoproteins
    • Noga A.A., Zhao Y., and Vance D.E. An unexpected requirement for phosphatidylethanolamine N-methyltransferase in the secretion of very low density lipoproteins. J Biol Chem 277 (2002) 42358-42365
    • (2002) J Biol Chem , vol.277 , pp. 42358-42365
    • Noga, A.A.1    Zhao, Y.2    Vance, D.E.3
  • 39
    • 0032538421 scopus 로고    scopus 로고
    • Biochemical and evolutionary significance of phospholipid methylation
    • Walkey C.J., Yu L., Agellon L.B., and Vance D.E. Biochemical and evolutionary significance of phospholipid methylation. J Biol Chem 273 (1998) 27043-27046
    • (1998) J Biol Chem , vol.273 , pp. 27043-27046
    • Walkey, C.J.1    Yu, L.2    Agellon, L.B.3    Vance, D.E.4
  • 40
    • 14044265120 scopus 로고    scopus 로고
    • Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids
    • Kapadia S.B., and Chisari F.V. Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids. Proc Natl Acad Sci USA 102 (2005) 2561-2566
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2561-2566
    • Kapadia, S.B.1    Chisari, F.V.2
  • 41
    • 0036165333 scopus 로고    scopus 로고
    • Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein
    • Okuda M., Li K., Beard M.R., Showalter L.A., Scholle F., Lemon S.M., et al. Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology 122 (2002) 366-375
    • (2002) Gastroenterology , vol.122 , pp. 366-375
    • Okuda, M.1    Li, K.2    Beard, M.R.3    Showalter, L.A.4    Scholle, F.5    Lemon, S.M.6
  • 42
    • 8544254757 scopus 로고    scopus 로고
    • In situ detection of lipid peroxidation in chronic hepatitis C: correlation with pathological features
    • Paradis V., Mathurin P., Kollinger M., Imbert-Bismut F., Charlotte F., Piton A., et al. In situ detection of lipid peroxidation in chronic hepatitis C: correlation with pathological features. J Clin Pathol 50 (1997) 401-406
    • (1997) J Clin Pathol , vol.50 , pp. 401-406
    • Paradis, V.1    Mathurin, P.2    Kollinger, M.3    Imbert-Bismut, F.4    Charlotte, F.5    Piton, A.6
  • 43
    • 34548788465 scopus 로고    scopus 로고
    • Proteomic profiling of human liver biopsies: hepatitis C virus-induced fibrosis and mitochondrial dysfunction
    • Diamond D.L., Jacobs J.M., Paeper B., Proll S.C., Gritsenko M.A., Carithers Jr. R.L., et al. Proteomic profiling of human liver biopsies: hepatitis C virus-induced fibrosis and mitochondrial dysfunction. Hepatology 46 (2007) 649-657
    • (2007) Hepatology , vol.46 , pp. 649-657
    • Diamond, D.L.1    Jacobs, J.M.2    Paeper, B.3    Proll, S.C.4    Gritsenko, M.A.5    Carithers Jr., R.L.6
  • 44
    • 39549121798 scopus 로고    scopus 로고
    • Assessment of in vivo 1H magnetic resonance spectroscopy in the liver: a review
    • Fischbach F., and Bruhn H. Assessment of in vivo 1H magnetic resonance spectroscopy in the liver: a review. Liver Int 28 (2008) 297-307
    • (2008) Liver Int , vol.28 , pp. 297-307
    • Fischbach, F.1    Bruhn, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.