Atorvastatin attenuates oxidative stress in Alzheimer's disease

Journal of Medical Colleges of PLA

Volumn 23, Issue 1, 2008, Pages 31-37

  Zhiyou, Cai ^a   Yong, Yan ^a   Yonglong, Wang ^a  

^a THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Atorvastatin; Matondialdehyde; Oxidized low density lipoprotein; Superoxide dismutase

Indexed keywords

ACETYLCHOLINESTERASE; ATORVASTATIN; LIPID; MALONALDEHYDE; OXIDIZED LOW DENSITY LIPOPROTEIN; SUPEROXIDE DISMUTASE;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BLOOD SAMPLING; DEMENTIA; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HYPERLIPIDEMIA; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NEUROPROTECTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

EID: 71249101795     PISSN: 10001948     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1000-1948(08)60006-4     Document Type: Article

References (35)

1. Chen CY, Jang JH, Park MH, et al. Attenuation of Abeta-induced apoptosis of plant extract (Saengshik) mediated by the inhibition of mitochondrial dysfunction and antioxidative effect. Ann N Y Acad Sci 2007, 1095:399-411.
2. Luo L, Huang YM Effect of resveratrol on the cognitive ability of Alzheimeros mice. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2006, 31(4):566-569. (In Chinese).
3. Ouyang S, Sun LS, Guo SL, et al. Effects of timosaponins on learning and memory abilities of rats with dementia induced by lateral cerebral ventricular injection of amyloid beta-peptide. Di Yi Jun Yi Da Xue Xue Bao 2005, 25(2):121-126. (In Chinese).
4. Souza-Costa DC, Figueiredo-Lopes L, Alves-Filho JC, et al. Protective effects of atorvastatin in rat models of acute pulmonary embolism: involvement of matrix metalloproteinase-9. Crit Care Med 2007, 35(1):239-245.
5. Meng RS, Li QM, Wei CX, et al. Clinical observation and mechanism study on treatment of senile dementia with Naohuandan. Zhongguo Jie He Yi Xue Za Zhi 2005, 11(2):111-116. (In Chinese).
6. Wang DL, Ling ZQ, Cao FY, et al. Melatonin attenuates isoproterenol-induced protein kinase A overactivation and tau hyperphosphorylation in rat brain. J Pineal Res 2004, 37(1):11-16.
7. Schuessel K, Schafer S, Bayer TA, et al. Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice. Neurobiol Dis 2005, 18(1):89-99.
8. Zhang Z, Yu CX Effect of melatonin on learning and memory impairment induced by aluminum chloride and its mechanism. Yao Xue Xue Bao 2002, 37(9):682-686. (In Chinese).
9. Delibas N, Ozcankaya R, Altuntas I Clinical importance of erythrocyte malondialdehyde levels as a marker for cognitive deterioration in patients with dementia of Alzheimer type: a repeated study in 5-year interval. Clin Biochem 2002, 35(2):137-141.
10. Ozcankaya R, Delibas N Malondialdehyde, superoxide dismutase, melatonin, iron, copper, and zinc blood concentrations in patients with Alzheimer disease: cross-sectional study. Croat Med J 2002, 43(1):28-32.
11. Fernandes MA, Proenca MT, Nogueira AJ, et al. Influence of apolipoprotein E genotype on blood redox status of Alzheimer's disease patients. Int J Mol Med 1999, 4(2):179-186.
12. Calabrese V, Guagliano E, Sapienza M, et al. Redox regulation of cellular stress response in neurondegenerative disorders. Ital J Biochem 2006, 55(3-4):263-282.
13. Zhu X, Lee HG, Moreira PI, et al. Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on " aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice" Free Radic Biol Med 2006, 40(5):737-739.
14. Loh KP, Huang SH, De Silva R, et al. Oxidative stress: apoptosis in neuronal injury. Curr Alzheimer Res 2006, 3(4):327-337.
15. Koliatsos VE, Kecojevic A, Troncoso JC, et al. Early involvement of small inhibitory cortical interneurons in Alzheimer's disease. Acta Neuropathol (Berl) 2006, 112(2):147-162.
16. Huber A, Stuchbury G, Burkle A, et al. Neuroprotective therapies for Alzheimer's disease. Curr Pharm Des 2006, 12(6):705-717.
17. Calabrese V, Guagliano E, Sapienza M, et al. Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes. Neurochem Res 2007, 32(4-5):757-773.
18. Chen X, Stern D, Yan SD Mitochondrial dysfunction and Alzheimer's disease. Curr Alzheimer Res 2006, 3(5):515-520.
19. Naderi J, Lopez C, Pandey S Chronically increased oxidative stress in fibroblasts from Alzheimer's disease patients causes early senescence and renders resistance to apoptosis by oxidative stress. Mech Ageing Dev 2006, 127(1):25-35.
20. Schuessel K, Frey C, Jourdan C, et al. Aging sensitizes toward ROS formation and lipid peroxidation in PS1M146L transgenic mice. Free Radic Biol Med 2006, 40(5):850-862.
21. Zablocka A Alzheimer's disease as neurondegenerative disorder. Postepy Hig Med Dosw 2006, 60:209-216.
22. Lambert MP, Velasco PT, Chang L, et al. Monoclonal antibodies that target pathological assemblies of Abeta. J Neurochem 2007, 100(1):23-35.
23. De Felice FG, Velasco PT, Lambert MP, et al. Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine. J Biol Chem 2007, 282(15):11590-11601.
24. Smith WW, Gorospe M, Kusiak JW Signaling mechanisms underlying Abeta toxicity: potential therapeutic targets for Alzheimer's disease. CNS Neurol Disord Drug Targets 2006, 5(3):355-361.
25. Guidi I, Galimberti D, Lonati S, et al. Oxidative imbalance in patients with mild cognitive impairment and Alzheimer's disease. Neurobiol Aging 2006, 27(2):262-269.
26. Ohta S, Ohsawa I Dysfunction of mitochondria and oxidative stress in the pathogenesis of Alzheimer's disease: on defects in the cytochrome c oxidase complex and aldehyde detoxification. J Alzheimers Dis 2006, 9(2):155-166.
27. Pietzsch J, Bergmann R, Wuest F, et al. Catabolism of native and oxidized low density lipoproteins: in vivo insights from small animal positron emission tomography studies. Amino Acids 2005, 29(4):389-404.
28. Panza F, Capurso C, D'Introno A, et al. Total cholesterol levels and the risk of mild cognitive impairment and Alzheimer's disease. J Am Geriatr Soc 2007, 55(1):133-135.
29. Panza F, Capurso C, D'Introno A, et al. Dietary polyunsaturated fatty acid supplementation, predementia syndromes, and Alzheimer's disease. J Am Geriatr Soc 2007, 55(3):469-470.
30. Panza F, D'Introno A, Colacicco AM, et al. Lipid metabolism in cognitive decline and dementia. Brain Res Rev 2006, 51(2):275-292.
31. Solfrizzi V, Colacicco AM, D'Introno A, et al. Dietary intake of unsaturated fatty acids and age-related cognitive decline: a 8.5-year follow-up of the Italian longitudinal study on aging. Neurobiol Aging 2006, 27(11):1694-1704.
32. Sun YX, Minthon L, Wallmark A, et al. Inflammatory markers in matched plasma and cerebrospinal fluid from patients with Alzheimer's disease. Dement Geriatr Cogn Disord 2003, 16(3):136-144.
33. Draczynska-Lusiak B, Doung A, Sun AY Oxidized lipoproteins may play a role in neuronal cell death in Alzheimer disease. Mol Chem Neuropathol 1998, 33(2):139-148.
34. Keller JN, Hanni KB, Markesbery WR Oxidized low-density lipoprotein induces neuronal death: implications for calcium, reactive oxygen species, and caspases. J Neurochem 1999, 72(6):2601-2609.
35. Keller JN, Hanni KB, Markesbery WR Impaired proteasome function in Alzheimer's disease. J Neurochem 2000, 75(1):436-439.