-
1
-
-
0031883829
-
Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted
-
Amalfitano A., Hauser M.A., Hu H., Serra D., Begy C.R., and Chamberlain J.S. Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted. J. Virol. 72 2 (1998) 926-933
-
(1998)
J. Virol.
, vol.72
, Issue.2
, pp. 926-933
-
-
Amalfitano, A.1
Hauser, M.A.2
Hu, H.3
Serra, D.4
Begy, C.R.5
Chamberlain, J.S.6
-
2
-
-
44849140020
-
Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent
-
Appledorn D.M., Kiang A., McBride A., Jiang H., Seregin S., Scott J.M., Stringer R., Kousa Y., Hoban M., Frank M.M., and Amalfitano A. Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent. Gene Ther. 15 12 (2008) 885-901
-
(2008)
Gene Ther.
, vol.15
, Issue.12
, pp. 885-901
-
-
Appledorn, D.M.1
Kiang, A.2
McBride, A.3
Jiang, H.4
Seregin, S.5
Scott, J.M.6
Stringer, R.7
Kousa, Y.8
Hoban, M.9
Frank, M.M.10
Amalfitano, A.11
-
3
-
-
57049106918
-
Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors
-
Appledorn D.M., McBride A., Seregin S., Scott J.M., Schuldt N., Kiang A., Godbehere S., and Amalfitano A. Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors. Gene Ther. 15 24 (2008) 1606-1617
-
(2008)
Gene Ther.
, vol.15
, Issue.24
, pp. 1606-1617
-
-
Appledorn, D.M.1
McBride, A.2
Seregin, S.3
Scott, J.M.4
Schuldt, N.5
Kiang, A.6
Godbehere, S.7
Amalfitano, A.8
-
4
-
-
71149116830
-
TRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses
-
Appledorn D.M., Patial S., Godbehere S., Parameswaran N., and Amalfitano A. TRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses. J. Innate Immunity 1 4 (2009) 376-388
-
(2009)
J. Innate Immunity
, vol.1
, Issue.4
, pp. 376-388
-
-
Appledorn, D.M.1
Patial, S.2
Godbehere, S.3
Parameswaran, N.4
Amalfitano, A.5
-
5
-
-
49649109923
-
Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo
-
Appledorn D.M., Patial S., McBride A., Godbehere S., Van Rooijen N., Parameswaran N., and Amalfitano A. Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo. J. Immunol. 181 3 (2008) 2134-2144
-
(2008)
J. Immunol.
, vol.181
, Issue.3
, pp. 2134-2144
-
-
Appledorn, D.M.1
Patial, S.2
McBride, A.3
Godbehere, S.4
Van Rooijen, N.5
Parameswaran, N.6
Amalfitano, A.7
-
7
-
-
33846309241
-
Toll-like receptor 9 triggers an innate immune response to helper-dependent adenoviral vectors
-
Cerullo V., Seiler M.P., Mane V., Brunetti-Pierri N., Clarke C., Bertin T.K., Rodgers J.R., and Lee B. Toll-like receptor 9 triggers an innate immune response to helper-dependent adenoviral vectors. Mol. Ther. 15 2 (2007) 378-385
-
(2007)
Mol. Ther.
, vol.15
, Issue.2
, pp. 378-385
-
-
Cerullo, V.1
Seiler, M.P.2
Mane, V.3
Brunetti-Pierri, N.4
Clarke, C.5
Bertin, T.K.6
Rodgers, J.R.7
Lee, B.8
-
8
-
-
0035702887
-
Complement activation by recombinant adenoviruses
-
Cichon G., Boeckh-Herwig S., Schmidt H.H., Wehnes E., Muller T., Pring-Akerblom P., and Burger R. Complement activation by recombinant adenoviruses. Gene Ther. 8 23 (2001) 1794-1800
-
(2001)
Gene Ther.
, vol.8
, Issue.23
, pp. 1794-1800
-
-
Cichon, G.1
Boeckh-Herwig, S.2
Schmidt, H.H.3
Wehnes, E.4
Muller, T.5
Pring-Akerblom, P.6
Burger, R.7
-
9
-
-
27744548418
-
Neutrophils interact with adenovirus vectors via Fc receptors and complement receptor 1
-
Cotter M.J., Zaiss A.K., and Muruve D.A. Neutrophils interact with adenovirus vectors via Fc receptors and complement receptor 1. J. Virol. 79 23 (2005) 14622-14631
-
(2005)
J. Virol.
, vol.79
, Issue.23
, pp. 14622-14631
-
-
Cotter, M.J.1
Zaiss, A.K.2
Muruve, D.A.3
-
10
-
-
16344373567
-
PEGylated helper-dependent adenoviral vectors: highly efficient vectors with an enhanced safety profile
-
Croyle M.A., Le H.T., Linse K.D., Cerullo V., Toietta G., Beaudet A., and Pastore L. PEGylated helper-dependent adenoviral vectors: highly efficient vectors with an enhanced safety profile. Gene Ther. 12 7 (2005) 579-587
-
(2005)
Gene Ther.
, vol.12
, Issue.7
, pp. 579-587
-
-
Croyle, M.A.1
Le, H.T.2
Linse, K.D.3
Cerullo, V.4
Toietta, G.5
Beaudet, A.6
Pastore, L.7
-
12
-
-
68249158537
-
Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo
-
Di Paolo N.C., Miao E.A., Iwakura Y., Murali-Krishna K., Aderem A., Flavell R.A., Papayannopoulou T., and Shayakhmetov D.M. Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo. Immunity 31 1 (2009) 110-121
-
(2009)
Immunity
, vol.31
, Issue.1
, pp. 110-121
-
-
Di Paolo, N.C.1
Miao, E.A.2
Iwakura, Y.3
Murali-Krishna, K.4
Aderem, A.5
Flavell, R.A.6
Papayannopoulou, T.7
Shayakhmetov, D.M.8
-
13
-
-
0346256668
-
Liver toxicities typically induced by first-generation adenoviral vectors can be reduced by use of E1, E2b-deleted adenoviral vectors
-
Everett R.S., Hodges B.L., Ding E.Y., Xu F., Serra D., and Amalfitano A. Liver toxicities typically induced by first-generation adenoviral vectors can be reduced by use of E1, E2b-deleted adenoviral vectors. Hum. Gene Ther. 14 18 (2003) 1715-1726
-
(2003)
Hum. Gene Ther.
, vol.14
, Issue.18
, pp. 1715-1726
-
-
Everett, R.S.1
Hodges, B.L.2
Ding, E.Y.3
Xu, F.4
Serra, D.5
Amalfitano, A.6
-
14
-
-
34247280398
-
Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression
-
Fan H., Luttrell L.M., Tempel G.E., Senn J.J., Halushka P.V., and Cook J.A. Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression. Mol. Immunol. 44 12 (2007) 3092-3099
-
(2007)
Mol. Immunol.
, vol.44
, Issue.12
, pp. 3092-3099
-
-
Fan, H.1
Luttrell, L.M.2
Tempel, G.E.3
Senn, J.J.4
Halushka, P.V.5
Cook, J.A.6
-
15
-
-
2342510314
-
Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways
-
Gao H., Sun Y., Wu Y., Luan B., Wang Y., Qu B., and Pei G. Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways. Mol. Cell 14 3 (2004) 303-317
-
(2004)
Mol. Cell
, vol.14
, Issue.3
, pp. 303-317
-
-
Gao, H.1
Sun, Y.2
Wu, Y.3
Luan, B.4
Wang, Y.5
Qu, B.6
Pei, G.7
-
16
-
-
38949207486
-
Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications
-
Hartman Z.C., Appledorn D.M., and Amalfitano A. Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications. Virus Res. 132 1-2 (2008) 1-14
-
(2008)
Virus Res.
, vol.132
, Issue.1-2
, pp. 1-14
-
-
Hartman, Z.C.1
Appledorn, D.M.2
Amalfitano, A.3
-
17
-
-
33846354137
-
Adenoviral infection induces a multi-faceted innate cellular immune response that is mediated by the toll-like receptor pathway in A549 cells
-
Hartman Z.C., Black E.P., and Amalfitano A. Adenoviral infection induces a multi-faceted innate cellular immune response that is mediated by the toll-like receptor pathway in A549 cells. Virology 358 2 (2007) 357-372
-
(2007)
Virology
, vol.358
, Issue.2
, pp. 357-372
-
-
Hartman, Z.C.1
Black, E.P.2
Amalfitano, A.3
-
18
-
-
33846799474
-
Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo
-
Hartman Z.C., Kiang A., Everett R.S., Serra D., Yang X.Y., Clay T.M., and Amalfitano A. Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo. J. Virol. 81 4 (2007) 1796-1812
-
(2007)
J. Virol.
, vol.81
, Issue.4
, pp. 1796-1812
-
-
Hartman, Z.C.1
Kiang, A.2
Everett, R.S.3
Serra, D.4
Yang, X.Y.5
Clay, T.M.6
Amalfitano, A.7
-
19
-
-
0034974898
-
Adenovirus vectors with the 100K gene deleted and their potential for multiple gene therapy applications
-
Hodges B.L., Evans H.K., Everett R.S., Ding E.Y., Serra D., and Amalfitano A. Adenovirus vectors with the 100K gene deleted and their potential for multiple gene therapy applications. J. Virol. 75 13 (2001) 5913-5920
-
(2001)
J. Virol.
, vol.75
, Issue.13
, pp. 5913-5920
-
-
Hodges, B.L.1
Evans, H.K.2
Everett, R.S.3
Ding, E.Y.4
Serra, D.5
Amalfitano, A.6
-
20
-
-
0031423398
-
Genomic DNA from mice: a comparison of recovery methods and tissue sources
-
Hofstetter J.R., Zhang A., Mayeda A.R., Guscar T., Nurnberger Jr. J.I., and Lahiri D.K. Genomic DNA from mice: a comparison of recovery methods and tissue sources. Biochem. Mol. Med. 62 2 (1997) 197-202
-
(1997)
Biochem. Mol. Med.
, vol.62
, Issue.2
, pp. 197-202
-
-
Hofstetter, J.R.1
Zhang, A.2
Mayeda, A.R.3
Guscar, T.4
Nurnberger Jr., J.I.5
Lahiri, D.K.6
-
21
-
-
0033540652
-
Persistence of an [E1-, polymerase-] adenovirus vector despite transduction of a neoantigen into immune-competent mice
-
Hu H., Serra D., and Amalfitano A. Persistence of an [E1-, polymerase-] adenovirus vector despite transduction of a neoantigen into immune-competent mice. Hum. Gene Ther. 10 3 (1999) 355-364
-
(1999)
Hum. Gene Ther.
, vol.10
, Issue.3
, pp. 355-364
-
-
Hu, H.1
Serra, D.2
Amalfitano, A.3
-
22
-
-
32444432723
-
Docosahexaenoic acid consumption inhibits deoxynivalenol-induced CREB/ATF1 activation and IL-6 gene transcription in mouse macrophages
-
Jia Q., Zhou H.R., Shi Y., and Pestka J.J. Docosahexaenoic acid consumption inhibits deoxynivalenol-induced CREB/ATF1 activation and IL-6 gene transcription in mouse macrophages. J. Nutr. 136 2 (2006) 366-372
-
(2006)
J. Nutr.
, vol.136
, Issue.2
, pp. 366-372
-
-
Jia, Q.1
Zhou, H.R.2
Shi, Y.3
Pestka, J.J.4
-
23
-
-
33748070532
-
Multiple innate inflammatory responses induced after systemic adenovirus vector delivery depend on a functional complement system
-
Kiang A., Hartman Z.C., Everett R.S., Serra D., Jiang H., Frank M.M., and Amalfitano A. Multiple innate inflammatory responses induced after systemic adenovirus vector delivery depend on a functional complement system. Mol. Ther. 14 4 (2006) 588-598
-
(2006)
Mol. Ther.
, vol.14
, Issue.4
, pp. 588-598
-
-
Kiang, A.1
Hartman, Z.C.2
Everett, R.S.3
Serra, D.4
Jiang, H.5
Frank, M.M.6
Amalfitano, A.7
-
24
-
-
0031473586
-
Controlling the complement system in inflammation
-
Kirschfink M. Controlling the complement system in inflammation. Immunopharmacology 38 1-2 (1997) 51-62
-
(1997)
Immunopharmacology
, vol.38
, Issue.1-2
, pp. 51-62
-
-
Kirschfink, M.1
-
25
-
-
0038069517
-
The role of capsid-endothelial interactions in the innate immune response to adenovirus vectors
-
Liu Q., Zaiss A.K., Colarusso P., Patel K., Haljan G., Wickham T.J., and Muruve D.A. The role of capsid-endothelial interactions in the innate immune response to adenovirus vectors. Hum. Gene Ther. 14 7 (2003) 627-643
-
(2003)
Hum. Gene Ther.
, vol.14
, Issue.7
, pp. 627-643
-
-
Liu, Q.1
Zaiss, A.K.2
Colarusso, P.3
Patel, K.4
Haljan, G.5
Wickham, T.J.6
Muruve, D.A.7
-
26
-
-
40349098959
-
Toll-like receptors differentially regulate GPCR kinases and arrestins in primary macrophages
-
Loniewski K., Shi Y., Pestka J., and Parameswaran N. Toll-like receptors differentially regulate GPCR kinases and arrestins in primary macrophages. Mol. Immunol. 45 8 (2008) 2312-2322
-
(2008)
Mol. Immunol.
, vol.45
, Issue.8
, pp. 2312-2322
-
-
Loniewski, K.1
Shi, Y.2
Pestka, J.3
Parameswaran, N.4
-
27
-
-
0031919928
-
Therapeutic inhibition of the complement system
-
Makrides S.C. Therapeutic inhibition of the complement system. Pharmacol. Rev. 50 1 (1998) 59-87
-
(1998)
Pharmacol. Rev.
, vol.50
, Issue.1
, pp. 59-87
-
-
Makrides, S.C.1
-
28
-
-
40449097257
-
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
-
Muruve D.A., Petrilli V., Zaiss A.K., White L.R., Clark S.A., Ross P.J., Parks R.J., and Tschopp J. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 452 7183 (2008) 103-107
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 103-107
-
-
Muruve, D.A.1
Petrilli, V.2
Zaiss, A.K.3
White, L.R.4
Clark, S.A.5
Ross, P.J.6
Parks, R.J.7
Tschopp, J.8
-
29
-
-
0035988785
-
Construction of first-generation adenoviral vectors
-
Ng P., and Graham F.L. Construction of first-generation adenoviral vectors. Methods Mol. Med. 69 (2002) 389-414
-
(2002)
Methods Mol. Med.
, vol.69
, pp. 389-414
-
-
Ng, P.1
Graham, F.L.2
-
30
-
-
33845960758
-
Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages
-
Parameswaran N., Pao C.S., Leonhard K.S., Kang D.S., Kratz M., Ley S.C., and Benovic J.L. Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages. J. Biol. Chem. 281 45 (2006) 34159-34170
-
(2006)
J. Biol. Chem.
, vol.281
, Issue.45
, pp. 34159-34170
-
-
Parameswaran, N.1
Pao, C.S.2
Leonhard, K.S.3
Kang, D.S.4
Kratz, M.5
Ley, S.C.6
Benovic, J.L.7
-
31
-
-
33750802401
-
Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes
-
Rajagopal K., Whalen E.J., Violin J.D., Stiber J.A., Rosenberg P.B., Premont R.T., Coffman T.M., Rockman H.A., and Lefkowitz R.J. Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes. Proc. Natl. Acad. Sci. U. S. A. 103 44 (2006) 16284-16289
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, Issue.44
, pp. 16284-16289
-
-
Rajagopal, K.1
Whalen, E.J.2
Violin, J.D.3
Stiber, J.A.4
Rosenberg, P.B.5
Premont, R.T.6
Coffman, T.M.7
Rockman, H.A.8
Lefkowitz, R.J.9
-
32
-
-
0345305297
-
A hemodynamic response to intravenous adenovirus vector particles is caused by systemic Kupffer cell-mediated activation of endothelial cells
-
Schiedner G., Bloch W., Hertel S., Johnston M., Molojavyi A., Dries V., Varga G., Van Rooijen N., and Kochanek S. A hemodynamic response to intravenous adenovirus vector particles is caused by systemic Kupffer cell-mediated activation of endothelial cells. Hum. Gene Ther. 14 17 (2003) 1631-1641
-
(2003)
Hum. Gene Ther.
, vol.14
, Issue.17
, pp. 1631-1641
-
-
Schiedner, G.1
Bloch, W.2
Hertel, S.3
Johnston, M.4
Molojavyi, A.5
Dries, V.6
Varga, G.7
Van Rooijen, N.8
Kochanek, S.9
-
33
-
-
70350164253
-
CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies
-
Seregin S.S., Aldhamen Y.A., Appledorn D.M., Schuldt N.J., McBride A.J., Bujold M., Godbehere S.S., and Amalfitano A. CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies. Gene Ther. 16 10 (2009) 1245-1259
-
(2009)
Gene Ther.
, vol.16
, Issue.10
, pp. 1245-1259
-
-
Seregin, S.S.1
Aldhamen, Y.A.2
Appledorn, D.M.3
Schuldt, N.J.4
McBride, A.J.5
Bujold, M.6
Godbehere, S.S.7
Amalfitano, A.8
-
34
-
-
63949084441
-
Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy
-
Seregin S.S., Appledorn D.M., McBride A.J., Schuldt N.J., Aldhamen Y.A., Voss T., Wei J., Bujold M., Nance W., Godbehere S., and Amalfitano A. Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy. Mol. Ther. 17 4 (2009) 685-696
-
(2009)
Mol. Ther.
, vol.17
, Issue.4
, pp. 685-696
-
-
Seregin, S.S.1
Appledorn, D.M.2
McBride, A.J.3
Schuldt, N.J.4
Aldhamen, Y.A.5
Voss, T.6
Wei, J.7
Bujold, M.8
Nance, W.9
Godbehere, S.10
Amalfitano, A.11
-
35
-
-
38049030654
-
Mechanism of adenovirus neutralization by Human alpha-defensins
-
Smith J.G., and Nemerow G.R. Mechanism of adenovirus neutralization by Human alpha-defensins. Cell Host Microbe 3 1 (2008) 11-19
-
(2008)
Cell Host Microbe
, vol.3
, Issue.1
, pp. 11-19
-
-
Smith, J.G.1
Nemerow, G.R.2
-
36
-
-
40449114333
-
Characterization of a novel anti-human TNF-alpha murine monoclonal antibody with high binding affinity and neutralizing activity
-
Song M.Y., Park S.K., Kim C.S., Yoo T.H., Kim B., Kim M.S., Kim Y.S., Kwag W.J., Lee B.K., and Baek K. Characterization of a novel anti-human TNF-alpha murine monoclonal antibody with high binding affinity and neutralizing activity. Exp. Mol. Med. 40 1 (2008) 35-42
-
(2008)
Exp. Mol. Med.
, vol.40
, Issue.1
, pp. 35-42
-
-
Song, M.Y.1
Park, S.K.2
Kim, C.S.3
Yoo, T.H.4
Kim, B.5
Kim, M.S.6
Kim, Y.S.7
Kwag, W.J.8
Lee, B.K.9
Baek, K.10
-
37
-
-
31344463886
-
Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling
-
Wang Y., Tang Y., Teng L., Wu Y., Zhao X., and Pei G. Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling. Nat. Immunol. 7 2 (2006) 139-147
-
(2006)
Nat. Immunol.
, vol.7
, Issue.2
, pp. 139-147
-
-
Wang, Y.1
Tang, Y.2
Teng, L.3
Wu, Y.4
Zhao, X.5
Pei, G.6
-
38
-
-
0347480382
-
Intravenous administration of replication-incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance
-
Wolins N., Lozier J., Eggerman T.L., Jones E., Aguilar-Cordova E., and Vostal J.G. Intravenous administration of replication-incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance. Br. J. Haematol. 123 5 (2003) 903-905
-
(2003)
Br. J. Haematol.
, vol.123
, Issue.5
, pp. 903-905
-
-
Wolins, N.1
Lozier, J.2
Eggerman, T.L.3
Jones, E.4
Aguilar-Cordova, E.5
Vostal, J.G.6
|