Focal epilepsy in the Belgian shepherd: Evidence for simple Mendelian inheritance

Journal of Small Animal Practice

Volumn 50, Issue 12, 2009, Pages 655-661

  Berendt, M ^a   Gullov C H ^a   Fredholm, M ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ANIMAL DISEASE; ARTICLE; BREEDING; DOG; DOG DISEASE; FEMALE; FOCAL EPILEPSY; GENETIC PREDISPOSITION; GENETICS; MALE; PEDIGREE; PREVALENCE; SEIZURE;

ANIMALS; BREEDING; DOG DISEASES; DOGS; EPILEPSIES, PARTIAL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; MALE; PEDIGREE; PREVALENCE; SEIZURES;

CANIDAE; CANIS FAMILIARIS;

EID: 71149111174     PISSN: 00224510     EISSN: 17485827     Source Type: Journal    
DOI: 10.1111/j.1748-5827.2009.00849.x     Document Type: Article

References (31)

1. Andermann, F., Kobayashi, E. & Andermann, E. (2005) Genetic focal epilepsies: state of the art and paths to the future. Epilepsia 46, 61 67
2. Berendt, M., Gredal, H., Pedersen, L. G., Alban, L. & Alving, J. (2002) A cross-sectional study ofepilepsy in Danish Labrador Retrievers: prevalence and selected risk factors. Journal of Veterinary Internal Medicine 16, 262 268
3. Berendt, M., Gredal, H. & Alving, J. (2004) Characteristics and phenomenology of epileptic partial seizures in dogs: similarities with human seizure semiology. Epilepsy Research 61, 167 173
4. Berendt, M., Gulløv, C. H., Christensen, S. L. K., Gudmundsdottir, H., Gredal, H., Fredholm, M. & Alban, L. (2008) Prevalence and characteristics of epilepsy in the Belgian shepherd variants Groenendael and Tervueren born in Denmark 1995-2004. Acta Veterinaria Scandinavica 50, 51
5. Bercovic, S. F. & Scheffer, I. E. (1997) Genetics of human partial epilepsy. Current Opinion in Neurology 10, 110 114
6. Bercovic, S. F. & Scheffer, I. E. (2004) Genetics of the epilepsies. Epilepsia 42, 16 23
7. Bercovic, S. F., Serratosa, J. M., Phillips, H. A., Xiong, L., Andermann, E., Díaz-Otero, F., Gómez-Garre, P., Martin, M., Fernández-Bullido, Y., Andermann, F., Lopes-Cendes, I., Dubeau, F., Desbiens, R., Scheffer, I. E., Wallace, R. H., Mulley, J. C. & Pandolfo, M. (2004) Familial partial epilepsy with variable foci: clinical features and linkage to chromosome 22q12. Epilepsia 45, 1054 1060
8. Bielfelt, S. W., Redman, H. C. & McClellan, R. O. (1971) Sire- and sex-related differences in rates of epileptiform seizures in a purebred beagle dog colony. American Journal of Veterinary Research 32, 2039 2048
9. Blume, W. T., Lüders, H. O., Mizrahi, E., Tassinari, C., Van Emde Boas, W. & Engel, J. (2001) Glossary of descriptive terminology for ictal semiology: report of the ILAE task force on classification and terminology. Epilepsia 42, 1212 1218 (Pubitemid 32951809)
10. Casal, M. L., Munuve, R. M., Janis, A. M., Werner, P. & Henthorn, P. S. (2006) Epilepsy in Irish wolfhounds. Journal of Veterinary Internal Medicine 20, 131 135
11. Chandler, K. (2006) Canine epilepsy: What can we learn from human seizure disorders? Veterinary Journal 172, 207 217
12. Commission on Epidemiology and Prognosis, International League Against Epilepsy (ILAE) 1993) Guidelines for epidemiologic studies on epilepsy. Epilepsia 34, 592 596
13. Commission on Classification and Terminology, International League Against Epilepsy (ILAE) 2009 www.ilae.org/classification
14. Famula, T. R., Oberbauer, A. M. & Brown, K. N. (1997) Heritability of epileptic seizures in the Belgian Tervueren. Journal of Small Animal Practice 38, 349 352
15. Famula, T. R. & Oberbauer, A. M. (1998) Reducing the incidence of epileptic seizures in the Belgian Tervueren through selection. Preventive Veterinary Medicine 33, 251 259
16. Famula, T. R. & Oberbauer, A. M. (2000) Segregation analysis of epilepsy in the Belgian Tervueren dog. Veterinary Record 147, 218 221
17. Gargus, J. J. (2003) Unraveling monogenetic channelopathies and their implications for complex polygenic disease. American Journal of Human Genetics 72, 785 803
18. Hall, S. J. & Wallace, M. E. (1996) Canine epilepsy: a genetic counseling program for keeshonds. Veterinary Record 138, 358 360
19. Jaggy, A., Faissler, D., Gaillard, C., Srenk, P. & Graber, H. (1998) Genetic aspects of idiopathic epilepsy in Labrador retrievers. Journal of Small Animal Practice 39, 275 280
20. Jokinen, T. S., Metsahonkala, L., Bergamasco, L., Viitmaa, R., Syrja, P., Lohi, H., Snellman, M., Jeserewics, J. & Cizinauskas, S. (2007) Benign familial juvenile epilepsy in Lagotto Romagnolo dogs. Journal of Veterinary Internal Medicine 21, 464 471
21. Kathmann, I., Jaggy, A., Busato, A., Bartschi, M. & Gaillard, C. (1999) Clinical and genetic investigations of idiopathic epilepsy in the Bernese mountain dog. Journal of Small Animal Practice 40, 319 325
22. Licht, B. G., Licht, M. H., Harper, K. M., Lin, S., Curtin, J. J., Hyson, L. L. & Willard, K. (2002) Clinical presentations of naturally occurring canine seizures: similarities to human seizures. Epilepsy Behavior 3, 460 470
23. Lindblad-Toh, K., Wade, C. M., Mikkelsen, T. S., Karlsson, E. K., Jaffe, D. B., Kamal, M., Clamp, M., Chang, J. L., Kulbokas, E. J., Zody, M. C., Mauceli, E., Xie, X., Breen, M., Wayne, R. K., Ostrander, E. A., Ponting, C. P., Galibert, F., Smith, D. R., DeJong, P. J., Kirkness, E., Alvarez, P., Biagi, T., Brocjman, W., Butler, J., Chin, C. W., Cook, A., Cuff, J., Daly, M. J., DeCaprio, D., Gnerre, S., Grabherr, M., Kellis, M., Kleber, M., Bardeleben, C., Goodstadt, L., Heger, A., Hitte, C., Kim, L., Koepfli, K. P., Parker, H. G., Pollinger, J. P., Searle, S. M. J., Sutter, N. B., Thomas, R., Webber, C., Lander, E. S. Broad Institute Genome Sequencing Platform 2005) Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 438, 803 819
24. Lohi, E. J., Fitzmaurice, S. N. Rusbridge, C., Vervoort, M., Turnbull, J., Zhao, X. C., Ianzano, L., Paterson, A. D., Sutter, N. B., Ostrander, E. A., André, C., Shelton, G. D., Ackerly, C. A., Scherer, S. W. & Minassian, B. A. (2005) Expanded repeat in canine epilepsy. Science 307, 81
25. Morita, T., Shimada, A., Takeuchi, T., Hikasa, Y., Sawada, M., Ohiwa, S., Takahashi, M., Kubo, N., Shibahara, T., Miyata, H. & Ohama, E. (2002) Cliniconeuropathologic findings of familial frontal lobe epilepsy in Shetland sheepdogs. Canadian Journal of Veterinary Research 66, 35 41
26. Oberbauer, A. M., Grossman, D. I., Irion, D. N., Schaffer, A. L., Eggleston, M. L. & Famula, T. R. (2003) The genetics of epilepsy in the Belgian Tervueren and sheepdog. Journal of Heredity 94, 57 63
27. Patterson, E. E., Armstrong, J., O'Brien, D. P., Roberts, M. C., Johnson, G. S. & Mickelson, J. R. (2005) Clinical description and mode of inheritance of idiopathic epilepsy in English Springer Spaniels. Journal of the American Veterinary Medical Association 226, 54 58
28. Picard, F., Baulac, S., Kahane, E., Hirsch, E., Sebastianelli, R., Thomas, P., Vigevano, F., Genton, P., Guerrini, R., Gericke, C. A., An, I., Rudolf, G., Herman, A., Brice, A. & Marescaux, C. (2000) Dominant partial epilepsies. A clinical, electrophysiological and genetic study of 19 European families. Brain 123, 1247 1262
29. Prasad, A. N., Prasad, C. & Stafstrom, C. E. (1999) Recent advances in the genetics of epilepsy: insights from human and animal studies. Epilepsia 40, 1329 1352
30. Scheffer, I. E., Phillips, H. A., OBrien, C. E., Saling, M. M., Wrennall, J. A., Wallace, R. H. & Mulley, J. C. (1998) Familial partial epilepsy with variable foci: a new partial epilepsy syndrome with suggestion of linkage to chromosome 2. Annals of Neurology 44, 890 899
31. van der Velden, M. (1968) Fits in Tervueren Shepherd dogs: a presumed hereditary trait. Journal of Small Animal Practice 9, 63 70