Clinical description and mode of inheritance of idiopathic epilepsy in English Springer Spaniels

Journal of the American Veterinary Medical Association

Volumn 226, Issue 1, 2005, Pages 54-58

  Patterson, Edward E ^a   Armstrong, P Jane ^a   O'Brien, Dennis P ^b   Roberts, Monica C ^a   Johnson, Gary S ^b   Mickelson, James R ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOSOMAL RECESSIVE INHERITANCE; CLINICAL FEATURE; DIAGNOSTIC APPROACH ROUTE; DOG; FOCAL EPILEPSY; GENETIC LINKAGE; GRAND MAL SEIZURE; MULTIFACTORIAL INHERITANCE; NONHUMAN; ONSET AGE; PEDIGREE; PSEUDOEPILEPTIC SEIZURE; SEGREGATION ANALYSIS;

AGE FACTORS; ANIMALS; BREEDING; DOG DISEASES; DOGS; EPILEPSY; FEMALE; GENES, RECESSIVE; GENETIC PREDISPOSITION TO DISEASE; LINKAGE (GENETICS); MALE; PEDIGREE; SEIZURES;

ANIMALIA; CANIS FAMILIARIS;

EID: 11144310727     PISSN: 00031488     EISSN: None     Source Type: Journal    
DOI: 10.2460/javma.2005.226.54     Document Type: Article

References (28)

1. Knowles K. Idiopathic epilepsy. Clin Tech Small Anim Pract 1998;13:144-151.
2. O'Brien DP. Pathogenesis of idiopathic epilepsy, in Proceedings. Am Coll Vet Intern Med Annu Forum 2003;404-406.
3. Steinlein OK. New insights into the molecular and genetic mechanisms underlying idiopathic epilepsies. Clin Genet 1998;54:169-175.
4. Mulley JC, Scheffer IE, Petrou S, et al. Channelopathies as a genetic cause of epilepsy. Curr Opin Neurol 2003;16:171-176.
5. Scheffer IE, Berkovic SF. The genetics of human epilepsy. Trends Pharmacol Sci 2003;24:428-433.
6. Biefelt SW, Redman HC, McClellan RO. Sire- and sex-related differences in rates of epileptiform seizures in a purebred Beagle dog colony. Am J Vet Res 1971;32:2039-2048.
7. Falco MJ, Barker J, Wallace ME. The genetics of epilepsy in the British Alsatian. J Small Anim Pract 1974;15:685-692.
8. Jaggy A, Faissler D, Gaillard C, et al. Genetic aspects of idiopathic epilepsy in Labrador Retrievers. J Small Anim Pract 1998;39:275-280.
9. Srenk P, Jaggy A. Interictal electroencephalographic findings in a family of Golden Retrievers. J Small Anim Pract 1996;37:317-321.
10. Kathmann I, Jaggy A, Busato A, et al. Clinical and genetic investigations of idiopathic epilepsy in the Bernese Mountain Dog. J Small Anim Pract 1999;40:319-325.
11. Famula TR, Oberbauer AM. Segregation analysis of epilepsy in the Belgian Tervuren dog. Vet Rec 2000;138:218-221.
12. Patterson EE, Da Y, Mickelson JR, et al. Clinical characteristics and inheritance of idiopathic epilepsy in Vizslas. J Vet Intern Med 2003;17:319-325.
13. Oberbauer AM, Grossman DI, Irion DN, et al. The genetics of epilepsy in the Belgian Tervuren and Sheepdog. J Hered 2003;94:57-63.
14. Podell M. Seizures in dogs. Vet Clin North Am Small Anim Pract 1996;26:779-807.
15. Davie AM. The singles method for segregation analysis under incomplete ascertainment. Ann Hum Genet 1979;42:507-512.
16. Nicholas FW. Simple segregation analysis: a review of its history and terminology. J Hered 1982;72:444-450.
17. Yao YC, Tai JJ. Bias correction for segregation ratio estimation in human genetics. Biometrics 2000;56:795-800.
18. Ott J. Computer-simulation methods in human linkage analysis. Proc Natl Acad Sci U S A 1989;86:4175-4178.
19. Strachan T, Read AP. Human molecular genetics. Oxford, England: BIOS Scientific Publishers Ltd, 1996;320-324, 479-505.
20. Berendt M, Gram L. Epilepsy and seizure classification in 63 dogs: a reappraisal of veterinary epilepsy terminology. J Vet Intern Med 1999;13:14-20.
21. Podell M. Epilepsy and seizure classification: a lesson from Leonardo. J Vet Intern Med 1999;13:3-4.
22. Berendt M, Pedersen LG, Alban L, et al. A cross-sectional study of epilepsy in Danish Labrador Retrievers: prevalence and selected risk factors. J Vet Intern Med 2002;16:262-268.
23. Lehmann-Horn F, Jurkat-Rott K. Voltage-gated ion channels and hereditary disease. Physiol Rev 1999;79:1317-1372.
24. Guyon R, Lorentzen TD, Hitte C, et al. A 1-Mb resolution radiation hybrid map of the canine genome. Proc Natl Acad Sci U S A 2003;100:5296-5301.
25. Lingaas F, Aarskaug T, Sletten M, et al. Genetic markers linked to neuronal ceroid lipofuscinosis in English Setter dogs. Anim Genet 1999;29:371-376.
26. Acland GM, Ray K, Mellersh CS, et al. Linkage analysis and comparative mapping of canine progressive rod-cone degeneration (prcd) establishes potential locus homology with retinitis pigmentosa (RP17) in humans. Proc Natl Acad Sci U S A 1998;95:3048-3053.
27. van De Sluis B, Rothuizen J, Pearson PL, et al. Identification of a new copper metabolism gene by positional cloning in a purebred dog population. Hum Mol Genet 2002;11:165-173.
28. Lingaas F, Comstock KE, Kirkness EF, et al. Renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd Dog. Hum Mol Genet 2003;12:3043-3053.