A twin study of depression and migraine: Evidence for a shared genetic vulnerability

Headache

Volumn 49, Issue 10, 2009, Pages 1493-1502

  Schur, Ellen A ^a   Noonan, Carolyn ^a   Buchwald, Dedra ^a   Goldberg, Jack ^b   Afari, Niloofar ^c  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Comorbidity; Depression; Genetics; Headache; Migraine

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; DEPRESSION; DIZYGOTIC TWINS; ENVIRONMENTAL FACTOR; FEMALE; GENETIC VARIABILITY; HEALTH SURVEY; HERITABILITY; HUMAN; MAJOR CLINICAL STUDY; MIGRAINE; MONOZYGOTIC TWINS; PREVALENCE; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; DEPRESSIVE DISORDER; DISEASES IN TWINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MIDDLE AGED; MIGRAINE DISORDERS; REGISTRIES; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC; YOUNG ADULT;

EID: 71049184798     PISSN: 00178748     EISSN: 15264610     Source Type: Journal    
DOI: 10.1111/j.1526-4610.2009.01425.x     Document Type: Article

References (42)

1. Hu XH, Markson LE, Lipton RB, Stewart WF, Berger ML. Burden of migraine in the United States: Disability and economic costs. Arch Intern Med. 1999 159 : 813 818.
2. Kessler RC, Frank RG. The impact of psychiatric disorders on work loss days. Psychol Med. 1997 27 : 861 873.
3. Breslau N, Lipton RB, Stewart WF, Schultz LR, Welch KMA. Comorbidity of migraine and depression - Investigating potential etiology and prognosis. Neurology. 2003 60 : 1308 1312.
4. Breslau N, Schultz LR, Stewart WF, Lipton RB, Lucia VC, Welch KMA. Headache and major depression - Is the association specific to migraine? Neurology. 2000 54 : 308 313.
5. Merikangas KR, Risch NJ, Merikangas JR, Weissman MM, Kidd KK. Migraine and depression: Association and familial transmission. J Psychiatr Res. 1988 22 : 119 129.
6. Radat F, Swendsen J. Psychiatric comorbidity in migraine: A review. Cephalalgia. 2005 25 : 165 178.
7. Fasmer OB. The prevalence of migraine in patients with bipolar and unipolar affective disorders. Cephalalgia. 2001 21 : 894 899.
8. Hamelsky SW, Lipton RB. Psychiatric comorbidity of migraine. Headache. 2006 46 : 1327 1333.
9. Sullivan PF, Neale MC, Kendler KS. Genetic epidemiology of major depression: Review and meta-analysis. Am J Psychiatry. 2000 157 : 1552 1562.
10. Stewart WF, Staffa J, Lipton RB, Ottman R. Familial risk of migraine: A population-based study. Ann Neurol. 1997 41 : 166 172.
11. Colson NJ, Fernandez F, Lea RA, Griffiths LR. The search for migraine genes: An overview of current knowledge. Cell Mol Life Sci. 2007 64 : 331 344. (Pubitemid 46440198)
12. Breslau N, Rasmussen BK. The impact of migraine - Epidemiology, risk factors, and co-morbidities. Neurology. 2001 56 : S4 S12.
13. Afari N, Noonan C, Goldberg J, et al. University of Washington Twin Registry: Construction and characteristics of a community-based twin registry. Twin Res Hum Genet. 2006 9 : 1023 1029.
14. Torgersen S. The determination of twin zygosity by means of a mailed questionnaire. Acta Genet Med Gemellol (Roma). 1979 28 : 225 236.
15. Reed T, Plassman BL, Tanner CM, Dick DM, Rinehart SA, Nichols WC. Verification of self-report of zygosity determined via DNA testing in a subset of the NAS-NRC twin registry 40 years later. Twin Res Hum Genet. 2005 8 : 362 367.
16. Neale M, Cardon L. Methodology for the Study of Twins and Families. Dordrecht : Kluwer Academic Press, 1992 : 109 132, 181 192.
17. Akaike H. Factor analysis and AIC. Psychometrika. 1987 52 : 327 332.
18. Neale NC, Boker SM, Xie G, Maes HH. MX: Statistical Modeling, 6th edn. Richmond, VA : VCU, 2004.
19. Brunner HG, van Driel MA. From syndrome families to functional genomics. Nat Rev Genet. 2004 5 : 545 551.
20. Hallstrand TS, Fischer ME, Wurfel MM, Afari N, Buchwald D, Goldberg J. Genetic pleiotropy between asthma and obesity in a community-based sample of twins. J Allergy Clin Immunol. 2005 116 : 1235 1241.
21. Tang ZH, Xiao P, Lei SF, et al. A bivariate whole-genome linkage scan suggests several shared genomic regions for obesity and osteoporosis. J Clin Endocrinol Metab. 2007 92 : 2751 2757.
22. Russell MB, Iselius L, Olesen J. Migraine without aura and migraine with aura are inherited disorders. Cephalalgia. 1996 16 : 305 309. (Pubitemid 26271250)
23. Gervil M, Ulrich V, Kaprio J, Olesen J, Russell MB. The relative role of genetic and environmental factors in migraine without aura. Neurology. 1999 53 : 995 999.
24. Mulder EJ, van Baal C, Gaistz D, et al. Genetic and environmental influences on migraine: A twin study across six countries. Twin Res. 2003 6 : 422 431.
25. Larsson B, Bille B, Pedersen NL. Genetic influence in headaches - A Swedish Twin Study. Headache. 1995 35 : 513 519.
26. Kendler KS, Gatz M, Gardner CO, Pedersen NL. A Swedish national twin study of lifetime major depression. Am J Psychiatry. 2006 163 : 109 114.
27. Holmans P, Weissman MM, Zubenko GS, et al. Genetics of recurrent early-onset major depression (GenRED): Final genome scan report. Am J Psychiatry. 2007 164 : 248 258.
28. Levinson DF, Evgrafov OV, Knowles JA, et al. Genetics of recurrent early-onset major depression (GenRED): Significant linkage on chromosome 15q25-q26 after fine mapping with single nucleotide polymorphism markers. Am J Psychiatry. 2007 164 : 259 264.
29. Abkevich V, Camp NJ, Hensel CH, et al. Predisposition locus for major depression at chromosome 12q22-12q23.2. Am J Hum Genet. 2003 73 : 1271 1281.
30. McGuffin P, Cohen S, Knight J. Homing in on depression genes. Am J Psychiatry. 2007 164 : 195 197.
31. Christiansen L, Tan QH, Iachina M, et al. Candidate gene polymorphisms in the serotonergic pathway: Influence on depression symptomatology in an elderly population. Biol Psychiatry. 2007 61 : 223 230.
32. Lesch KP, Bengel D, Heils A, et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science. 1996 274 : 1527 1531.
33. Caspi A, Sugden K, Moffitt TE, et al. Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science. 2003 301 : 386 389.
34. van den Maagdenberg A, Haan J, Terwindt GM, Ferrari MD. Migraine: Gene mutations and functional consequences. Curr Opin Neurol. 2007 20 : 299 305.
35. Wessman M, Kaunisto MA, Kallela M, Palotie A. The molecular genetics of migraine. Ann Med. 2004 36 : 462 473.
36. Marziniak M, Mossner R, Schmitt A, Lesch KP, Sommer C. A functional serotonin transporter gene polymorphism is associated with migraine with aura. Neurology. 2005 64 : 157 159.
37. Ogilvie A, Russell MB, Dhall P, et al. Altered allelic distributions of the serotonin transporter gene in migraine without aura and migraine with aura. Cephalalgia. 1998 18 : 23 26.
38. Tietjen GE, Brandes JL, Digre KB, et al. History of childhood maltreatment is associated with comorbid depression in women with migraine. Neurology. 2007 69 : 959 968.
39. Tietjen GE, Peterlin BL, Brandes JL, et al. Depression and anxiety: Effect on the migraine-obesity relationship. Headache. 2007 47 : 866 875.
40. Bigal ME, Lipton RB, Holland PR, Goadsby PJ. Obesity, migraine, and chronic migraine: Possible mechanisms of interaction. Neurology. 2007 68 : 1851 1861.
41. Kessler RC, Berglund P, Demler O, et al. The epidemiology of major depressive disorder: Results from the National Comorbidity Survey Replication (NCS-R). JAMA. 2003 289 : 3095 3105.
42. Stewart WF, Lipton RB, Celentano DD, Reed ML. Prevalence of migraine headache in the United States. Relation to age, income, race, and other sociodemographic factors. JAMA. 1992 267 : 64 69.