-
1
-
-
0023197081
-
Estimating a woman's risk of having a pregnancy associated with Down's syndrome using her age and serum alpha-fetoprotein level
-
Cuckle HS, Wald NJ, Thompson SG (1987) Estimating a woman's risk of having a pregnancy associated with Down's syndrome using her age and serum alpha-fetoprotein level. Br J Obstet Gynaecol 94: 387-402.
-
(1987)
Br J Obstet Gynaecol
, vol.94
, pp. 387-402
-
-
Cuckle, H.S.1
Wald, N.J.2
Thompson, S.G.3
-
2
-
-
0023726523
-
Maternal serum screening for Down's syndrome in early pregnancy
-
Wald NJ, Cuckle HS, Densem JW, Nanchahal K, Royston P, et al. (1988) Maternal serum screening for Down's syndrome in early pregnancy. BMJ 297: 883-887.
-
(1988)
BMJ
, vol.297
, pp. 883-887
-
-
Wald, N.J.1
Cuckle, H.S.2
Densem, J.W.3
Nanchahal, K.4
Royston, P.5
-
3
-
-
0030883821
-
Combining ultrasound and biochemistry in first-trimester screening for Down's syndrome
-
Wald NJ, Hackshaw AK (1997) Combining ultrasound and biochemistry in first-trimester screening for Down's syndrome. Prenat Diagn 17: 821-829.
-
(1997)
Prenat Diagn
, vol.17
, pp. 821-829
-
-
Wald, N.J.1
Hackshaw, A.K.2
-
4
-
-
67049158682
-
First-trimester Down syndrome screening performance in the Dutch population; how to achieve further improvement?
-
Wortelboer EJ, Koster MP, Stoutenbeek P, Elvers LH, Loeber JG, et al. (2009) First-trimester Down syndrome screening performance in the Dutch population; how to achieve further improvement? Prenat Diagn 29: 588-592.
-
(2009)
Prenat Diagn
, vol.29
, pp. 588-592
-
-
Wortelboer, E.J.1
Koster, M.P.2
Stoutenbeek, P.3
Elvers, L.H.4
Loeber, J.G.5
-
6
-
-
49949083716
-
Application of proteomics for the identification of differentially expressed protein markers for Down syndrome in maternal plasma
-
Kolialexi A, Tsangaris GT, Papantoniou N, Anagnostopoulos AK, Vougas K, et al. (2008) Application of proteomics for the identification of differentially expressed protein markers for Down syndrome in maternal plasma. Prenat Diagn 28: 691-698.
-
(2008)
Prenat Diagn
, vol.28
, pp. 691-698
-
-
Kolialexi, A.1
Tsangaris, G.T.2
Papantoniou, N.3
Anagnostopoulos, A.K.4
Vougas, K.5
-
7
-
-
69749098657
-
Bead-based multiplexed immunoassays to identify new biomarkers in maternal serum to improve first trimester Down syndrome screening
-
Koster MP, Pennings JL, Imholz S, Rodenburg W, Visser GH, et al. (2009) Bead-based multiplexed immunoassays to identify new biomarkers in maternal serum to improve first trimester Down syndrome screening. Prenat Diagn 29: 857-862.
-
(2009)
Prenat Diagn
, vol.29
, pp. 857-862
-
-
Koster, M.P.1
Pennings, J.L.2
Imholz, S.3
Rodenburg, W.4
Visser, G.H.5
-
8
-
-
34248148090
-
Proteomic analysis of maternal serum in down syndrome: Identification of novel protein biomarkers
-
Nagalla SR, Canick JA, Jacob T, Schneider KA, Reddy AP, et al. (2007) Proteomic analysis of maternal serum in down syndrome: identification of novel protein biomarkers. J Proteome Res 6: 1245-1257.
-
(2007)
J Proteome Res
, vol.6
, pp. 1245-1257
-
-
Nagalla, S.R.1
Canick, J.A.2
Jacob, T.3
Schneider, K.A.4
Reddy, A.P.5
-
9
-
-
1842528128
-
Proteomic determination of metabolic enzymes of the amnion cell: Basis for a possible diagnostic tool?
-
Oh JE, Fountoulakis M, Juranville JF, Rosner M, Hengstschlager M, et al. (2004) Proteomic determination of metabolic enzymes of the amnion cell: basis for a possible diagnostic tool? Proteomics 4: 1145-1158.
-
(2004)
Proteomics
, vol.4
, pp. 1145-1158
-
-
Oh, J.E.1
Fountoulakis, M.2
Juranville, J.F.3
Rosner, M.4
Hengstschlager, M.5
-
10
-
-
33747787748
-
Proteomic analysis of amniotic fluid in pregnancies with Down syndrome
-
Tsangaris GT, Karamessinis P, Kolialexi A, Garbis SD, Antsaklis A, et al. (2006) Proteomic analysis of amniotic fluid in pregnancies with Down syndrome. Proteomics 6: 4410-4419.
-
(2006)
Proteomics
, vol.6
, pp. 4410-4419
-
-
Tsangaris, G.T.1
Karamessinis, P.2
Kolialexi, A.3
Garbis, S.D.4
Antsaklis, A.5
-
11
-
-
33748196408
-
A combined approach to data mining of textual and structured data to identify cancer-related targets
-
Pospisil P, Iyer LK, Adelstein SJ, Kassis AI (2006) A combined approach to data mining of textual and structured data to identify cancer-related targets. BMC Bioinformatics 7: 354.
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 354
-
-
Pospisil, P.1
Iyer, L.K.2
Adelstein, S.J.3
Kassis, A.I.4
-
12
-
-
47249120110
-
Identification of candidate cancer genes involved in human retinoblastoma by data mining
-
Yang J, Zhao JJ, Zhu Y, Xiong W, Lin JY, et al. (2008) Identification of candidate cancer genes involved in human retinoblastoma by data mining. Childs Nerv Syst 24: 893-900.
-
(2008)
Childs Nerv Syst
, vol.24
, pp. 893-900
-
-
Yang, J.1
Zhao, J.J.2
Zhu, Y.3
Xiong, W.4
Lin, J.Y.5
-
13
-
-
0028078591
-
Dehydroepiandrosterone sulfotransferase in the developing human fetus: Quantitative biochemical and immunological characterization of the hepatic, renal, and adrenal enzymes
-
Barker EV, Hume R, Hallas A, Coughtrie WH (1994) Dehydroepiandrosterone sulfotransferase in the developing human fetus: quantitative biochemical and immunological characterization of the hepatic, renal, and adrenal enzymes. Endocrinology 134: 982-989.
-
(1994)
Endocrinology
, vol.134
, pp. 982-989
-
-
Barker, E.V.1
Hume, R.2
Hallas, A.3
Coughtrie, W.H.4
-
14
-
-
0034062068
-
Placental synthesis of oestriol in Down's syndrome pregnancies
-
Newby D, Aitken DA, Howatson AG, Connor JM (2000) Placental synthesis of oestriol in Down's syndrome pregnancies. Placenta 21: 263-267.
-
(2000)
Placenta
, vol.21
, pp. 263-267
-
-
Newby, D.1
Aitken, D.A.2
Howatson, A.G.3
Connor, J.M.4
-
15
-
-
39549121462
-
Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta
-
Malassine A, Frendo JL, Blaise S, Handschuh K, Gerbaud P, et al. (2008) Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta. Retrovirology 5: 6.
-
(2008)
Retrovirology
, vol.5
, pp. 6
-
-
Malassine, A.1
Frendo, J.L.2
Blaise, S.3
Handschuh, K.4
Gerbaud, P.5
-
16
-
-
7444230323
-
Trisomy 21 is associated with variable defects in cytotrophoblast differentiation along the invasive pathway
-
Wright A, Zhou Y, Weier JF, Caceres E, Kapidzic M, et al. (2004) Trisomy 21 is associated with variable defects in cytotrophoblast differentiation along the invasive pathway. Am J Med Genet A 130A: 354-364.
-
(2004)
Am J Med Genet A
, vol.130 A
, pp. 354-364
-
-
Wright, A.1
Zhou, Y.2
Weier, J.F.3
Caceres, E.4
Kapidzic, M.5
-
17
-
-
11144358198
-
A gene atlas of the mouse and human protein-encoding transcriptomes
-
Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, et al. (2004) A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A 101: 6062-6067.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 6062-6067
-
-
Su, A.I.1
Wiltshire, T.2
Batalov, S.3
Lapp, H.4
Ching, K.A.5
-
18
-
-
0037007048
-
Large-scale analysis of the human and mouse transcriptomes
-
Su AI, Cooke MP, Ching KA, Hakak Y, Walker JR, et al. (2002) Large-scale analysis of the human and mouse transcriptomes. Proc Natl Acad Sci U S A 99: 4465-4470.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 4465-4470
-
-
Su, A.I.1
Cooke, M.P.2
Ching, K.A.3
Hakak, Y.4
Walker, J.R.5
-
19
-
-
70149113077
-
-
R Development Core Team , R Foundation for Statistical Computing, Vienna, Austria
-
R Development Core Team (2009) R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria.
-
(2009)
R: A language and environment for statistical computing
-
-
-
20
-
-
47349105353
-
Anni 2.0: A multipurpose text-mining tool for the life sciences
-
Jelier R, Schuemie MJ, Veldhoven A, Dorssers LC, Jenster G, et al. (2008) Anni 2.0: a multipurpose text-mining tool for the life sciences. Genome Biol 9: R96.
-
(2008)
Genome Biol
, vol.9
-
-
Jelier, R.1
Schuemie, M.J.2
Veldhoven, A.3
Dorssers, L.C.4
Jenster, G.5
-
21
-
-
48449088232
-
PolySearch: A web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites
-
Cheng D, Knox C, Young N, Stothard P, Damaraju S, et al. (2008) PolySearch: a web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites. Nucleic Acids Res 36: W399-W405.
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Cheng, D.1
Knox, C.2
Young, N.3
Stothard, P.4
Damaraju, S.5
-
22
-
-
0034069495
-
Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, et al. (2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25: 25-29.
-
(2000)
Nat Genet
, vol.25
, pp. 25-29
-
-
Ashburner, M.1
Ball, C.A.2
Blake, J.A.3
Botstein, D.4
Butler, H.5
-
23
-
-
2542568705
-
The human plasma proteome: A nonredundant list developed by combination of four separate sources
-
Anderson NL, Polanski M, Pieper R, Gatlin T, Tirumalai RS, et al. (2004) The human plasma proteome: a nonredundant list developed by combination of four separate sources. Mol Cell Proteomics 3: 311-326.
-
(2004)
Mol Cell Proteomics
, vol.3
, pp. 311-326
-
-
Anderson, N.L.1
Polanski, M.2
Pieper, R.3
Gatlin, T.4
Tirumalai, R.S.5
-
24
-
-
0034970746
-
Placental and maternal serum inhibin-A and activin-A levels in Down's syndrome pregnancies
-
Dalgliesh GL, Aitken DA, Lyall F, Howatson AG, Connor JM (2001) Placental and maternal serum inhibin-A and activin-A levels in Down's syndrome pregnancies. Placenta 22: 227-234.
-
(2001)
Placenta
, vol.22
, pp. 227-234
-
-
Dalgliesh, G.L.1
Aitken, D.A.2
Lyall, F.3
Howatson, A.G.4
Connor, J.M.5
-
25
-
-
0030338258
-
Second trimester levels of maternal serum inhibin A, total inhibin, alpha inhibin precursor, and activin in Down's syndrome pregnancy
-
Lambert-Messerlian GM, Canick JA, Palomaki GE, Schneyer AL (1996) Second trimester levels of maternal serum inhibin A, total inhibin, alpha inhibin precursor, and activin in Down's syndrome pregnancy. J Med Screen 3: 58-62.
-
(1996)
J Med Screen
, vol.3
, pp. 58-62
-
-
Lambert-Messerlian, G.M.1
Canick, J.A.2
Palomaki, G.E.3
Schneyer, A.L.4
-
26
-
-
0032931820
-
Amniotic fluid levels of dimeric inhibins, pro-alpha C inhibin, activin A and follistatin in Down's syndrome
-
Wallace EM, D'Antona D, Shearing C, Evans LW, Thirunavukarasu P, et al. (1999) Amniotic fluid levels of dimeric inhibins, pro-alpha C inhibin, activin A and follistatin in Down's syndrome. Clin Endocrinol (Oxf) 50: 669-673.
-
(1999)
Clin Endocrinol (Oxf)
, vol.50
, pp. 669-673
-
-
Wallace, E.M.1
D'Antona, D.2
Shearing, C.3
Evans, L.W.4
Thirunavukarasu, P.5
-
27
-
-
0031958772
-
Second trimester levels of maternal serum total activin A and placental inhibin/activin alpha and betaA subunit messenger ribonucleic acids in Down syndrome pregnancy
-
Lambert-Messerlian GM, Luisi S, Florio P, Mazza V, Canick JA, et al. (1998) Second trimester levels of maternal serum total activin A and placental inhibin/activin alpha and betaA subunit messenger ribonucleic acids in Down syndrome pregnancy. Eur J Endocrinol 138: 425-429.
-
(1998)
Eur J Endocrinol
, vol.138
, pp. 425-429
-
-
Lambert-Messerlian, G.M.1
Luisi, S.2
Florio, P.3
Mazza, V.4
Canick, J.A.5
-
28
-
-
33846435147
-
Human placental lactogen is a first-trimester maternal serum marker of Down syndrome
-
Christiansen M, Sorensen TL, Norgaard-Pedersen B (2007) Human placental lactogen is a first-trimester maternal serum marker of Down syndrome. Prenat Diagn 27: 1-5.
-
(2007)
Prenat Diagn
, vol.27
, pp. 1-5
-
-
Christiansen, M.1
Sorensen, T.L.2
Norgaard-Pedersen, B.3
-
30
-
-
0031754087
-
Maternal serum placental growth hormone and insulinlike growth factor binding proteins 1 and 3 in pregnancies affected by fetal aneuploidy and other abnormalities: Implications for prenatal diagnosis of trisomy 21
-
Moghadam S, Engel W, Bougoussa M, Hennen G, Igout A, et al. (1998) Maternal serum placental growth hormone and insulinlike growth factor binding proteins 1 and 3 in pregnancies affected by fetal aneuploidy and other abnormalities: implications for prenatal diagnosis of trisomy 21. Fetal Diagn Ther 13: 291-297.
-
(1998)
Fetal Diagn Ther
, vol.13
, pp. 291-297
-
-
Moghadam, S.1
Engel, W.2
Bougoussa, M.3
Hennen, G.4
Igout, A.5
-
31
-
-
42349091709
-
Human placental growth hormone is increased in maternal serum in pregnancies affected by Down syndrome
-
Papadopoulou E, Sifakis S, Giahnakis E, Fragouli Y, Karkavitsas N, et al. (2008) Human placental growth hormone is increased in maternal serum in pregnancies affected by Down syndrome. Fetal Diagn Ther 23: 211-216.
-
(2008)
Fetal Diagn Ther
, vol.23
, pp. 211-216
-
-
Papadopoulou, E.1
Sifakis, S.2
Giahnakis, E.3
Fragouli, Y.4
Karkavitsas, N.5
-
32
-
-
0036173483
-
Raised maternal serum placenta growth factor concentration during the second trimester is associated with Down syndrome
-
Su YN, Hsu JJ, Lee CN, Cheng WF, Kung CC, et al. (2002) Raised maternal serum placenta growth factor concentration during the second trimester is associated with Down syndrome. Prenat Diagn 22: 8-12.
-
(2002)
Prenat Diagn
, vol.22
, pp. 8-12
-
-
Su, Y.N.1
Hsu, J.J.2
Lee, C.N.3
Cheng, W.F.4
Kung, C.C.5
-
33
-
-
71049143411
-
Placental Protein 13 as a first trimester screening marker for aneuploidy
-
In press
-
Koster MP, Wortelboer EJ, Cuckle HS, Stoutenbeek P, Visser GH, et al. (2009) Placental Protein 13 as a first trimester screening marker for aneuploidy. Prenat Diagn In press.
-
(2009)
Prenat Diagn
-
-
Koster, M.P.1
Wortelboer, E.J.2
Cuckle, H.S.3
Stoutenbeek, P.4
Visser, G.H.5
-
34
-
-
55449129556
-
Second trimester maternal serum ADAM12 levels in Down's syndrome pregnancies
-
Donalson K, Turner S, Wastell H, Cuckle H (2008) Second trimester maternal serum ADAM12 levels in Down's syndrome pregnancies. Prenat Diagn 28: 904-907.
-
(2008)
Prenat Diagn
, vol.28
, pp. 904-907
-
-
Donalson, K.1
Turner, S.2
Wastell, H.3
Cuckle, H.4
-
35
-
-
64249123581
-
Maternal serum ADAM12 (A disintegrin and metalloprotease) in chromosomally abnormal pregnancy at 11-13 weeks
-
Poon LC, Chelemen T, Minekawa R, Frisova V, Nicolaides KH (2009) Maternal serum ADAM12 (A disintegrin and metalloprotease) in chromosomally abnormal pregnancy at 11-13 weeks. Am J Obstet Gynecol 200: 508-6.
-
(2009)
Am J Obstet Gynecol
, vol.200
, pp. 508-516
-
-
Poon, L.C.1
Chelemen, T.2
Minekawa, R.3
Frisova, V.4
Nicolaides, K.H.5
-
36
-
-
41149138421
-
Maternal serum ADAM12s in the late first trimester of pregnancies with Trisomy 21
-
Spencer K, Cowans NJ, Stamatopoulou A (2008) Maternal serum ADAM12s in the late first trimester of pregnancies with Trisomy 21. Prenat Diagn 28: 422-424.
-
(2008)
Prenat Diagn
, vol.28
, pp. 422-424
-
-
Spencer, K.1
Cowans, N.J.2
Stamatopoulou, A.3
-
37
-
-
42049116341
-
First-trimester ADAM12s as early markers of trisomy 21: A promise still unfulfilled?
-
Spencer K, Cowans NJ, Uldbjerg N, Torring N (2008) First-trimester ADAM12s as early markers of trisomy 21: a promise still unfulfilled? Prenat Diagn 28: 338-342.
-
(2008)
Prenat Diagn
, vol.28
, pp. 338-342
-
-
Spencer, K.1
Cowans, N.J.2
Uldbjerg, N.3
Torring, N.4
-
38
-
-
69749127202
-
ADAM12s as a first-trimester screening marker of trisomy
-
Wortelboer EJ, Linskens IH, Koster MP, Stoutenbeek P, Cuckle H, et al. (2009) ADAM12s as a first-trimester screening marker of trisomy. Prenat Diagn 29: 866-869.
-
(2009)
Prenat Diagn
, vol.29
, pp. 866-869
-
-
Wortelboer, E.J.1
Linskens, I.H.2
Koster, M.P.3
Stoutenbeek, P.4
Cuckle, H.5
-
39
-
-
3543110316
-
Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome
-
Kahlem P, Sultan M, Herwig R, Steinfath M, Balzereit D, et al. (2004) Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome. Genome Res 14: 1258-1267.
-
(2004)
Genome Res
, vol.14
, pp. 1258-1267
-
-
Kahlem, P.1
Sultan, M.2
Herwig, R.3
Steinfath, M.4
Balzereit, D.5
-
40
-
-
3543097554
-
Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome
-
Lyle R, Gehrig C, Neergaard-Henrichsen C, Deutsch S, Antonarakis SE (2004) Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome. Genome Res 14: 1268-1274.
-
(2004)
Genome Res
, vol.14
, pp. 1268-1274
-
-
Lyle, R.1
Gehrig, C.2
Neergaard-Henrichsen, C.3
Deutsch, S.4
Antonarakis, S.E.5
-
41
-
-
34548084502
-
Genome-wide expression analysis of cultured trophoblast with trisomy 21 karyotype
-
Rozovski U, Jonish-Grossman A, Bar-Shira A, Ochshorn Y, Goldstein M, et al. (2007) Genome-wide expression analysis of cultured trophoblast with trisomy 21 karyotype. Hum Reprod 22: 2538-2545.
-
(2007)
Hum Reprod
, vol.22
, pp. 2538-2545
-
-
Rozovski, U.1
Jonish-Grossman, A.2
Bar-Shira, A.3
Ochshorn, Y.4
Goldstein, M.5
-
42
-
-
62849113692
-
Genotype-phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21
-
Lyle R, Bena F, Gagos S, Gehrig C, Lopez G, et al. (2009) Genotype-phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21. Eur J Hum Genet 17: 454-466.
-
(2009)
Eur J Hum Genet
, vol.17
, pp. 454-466
-
-
Lyle, R.1
Bena, F.2
Gagos, S.3
Gehrig, C.4
Lopez, G.5
-
43
-
-
7444231620
-
A chromosome 21 critical region does not cause specific Down syndrome phenotypes
-
Olson LE, Richtsmeier JT, Leszl J, Reeves RH (2004) A chromosome 21 critical region does not cause specific Down syndrome phenotypes. Science 306: 687-690.
-
(2004)
Science
, vol.306
, pp. 687-690
-
-
Olson, L.E.1
Richtsmeier, J.T.2
Leszl, J.3
Reeves, R.H.4
-
44
-
-
13144260659
-
Down syndrome and genetics - a case of linked histories
-
Patterson D, Costa AC (2005) Down syndrome and genetics - a case of linked histories. Nat Rev Genet 6: 137-147.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 137-147
-
-
Patterson, D.1
Costa, A.C.2
-
45
-
-
0031045614
-
Whither Down syndrome critical regions?
-
Shapiro BL (1997) Whither Down syndrome critical regions? Hum Genet 99: 421-423.
-
(1997)
Hum Genet
, vol.99
, pp. 421-423
-
-
Shapiro, B.L.1
|