Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta

Retrovirology

Volumn 5, Issue , 2008, Pages

  Malassiné, André ^a,b,e   Frendo, Jean Louis ^a,b,c,e   Blaise, Sandra ^d   Handschuh, Karen ^a,b   Gerbaud, Pascale ^a,b,e   Tsatsaris, Vassilis ^a,b,e   Heidmann, Thierry ^d,e   Evain Brion, Danièle ^a,b,e  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c CNRS   (France)

^d INSTITUT GUSTAVE ROUSSY   (France)

^e PremUP   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PLACENTA PROTEIN; SYNCYTIN 2; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; SYNCYTIN 2 PROTEIN, HUMAN;

ARTICLE; CELL DIFFERENTIATION; CELL FUSION; CONTROLLED STUDY; CYTOPLASM; CYTOTROPHOBLAST; ENDOGENOUS RETROVIRUS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOLOCALIZATION; IN VITRO STUDY; PLACENTA LOCALIZATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SECOND TRIMESTER PREGNANCY; SYNCYTIOTROPHOBLAST; TRISOMY 21; TROPHOBLAST; CELL CULTURE; CYTOLOGY; DOWN SYNDROME; FIRST TRIMESTER PREGNANCY; METABOLISM; PLACENTA; PREGNANCY;

HUMAN ENDOGENOUS RETROVIRUS; HUMAN ENDOGENOUS RETROVIRUS W;

CELL DIFFERENTIATION; CELLS, CULTURED; DOWN SYNDROME; ENDOGENOUS RETROVIRUSES; FEMALE; HUMANS; PLACENTA; PREGNANCY; PREGNANCY PROTEINS; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, SECOND; TROPHOBLASTS;

EID: 39549121462     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-5-6     Document Type: Article

References (31)

1. de Parseval N Heidmann T Human endogenous retroviruses: From infectious elements to human genes Cytogenet Genome Res 2005, 110(1-4):318-332. 10.1159/000084964 16093684
2. Lander ES Linton LM Birren B Nusbaum C Zody MC Baldwin J Devon K Dewar K Doyle M FitzHugh W Funke R Gage D Harris K Heaford A Howland J Kann L Lehoczky J LeVine R McEwan P McKernan K Meldrim J Mesirov JP Miranda C Morris W Naylor J Raymond C Rosetti M Santos R Sheridan A Sougnez C Stange-Thomann N Stojanovic N Subramanian A Wyman D Rogers J Sulston J Ainscough R Beck S Bentley D Burton J Clee C Carter N Coulson A Deadman R Deloukas P Dunham A Dunham I Durbin R French L Grafham D Gregory S Hubbard T Humphray S Hunt A Jones M Lloyd C McMurray A Matthews L Mercer S Milne S Mullikin JC Mungall A Plumb R Ross M Shownkeen R Sims S Waterston RH Wilson RK Hillier LW McPherson JD Marra MA Mardis ER Fulton LA Chinwalla AT Pepin KH Gish WR Chissoe SL Wendl MC Delehaunty KD Miner TL Delehaunty A Kramer JB Cook LL Fulton RS Johnson DL Minx PJ Clifton SW Hawkins T Branscomb E Predki P Richardson P Wenning S Slezak T Doggett N Cheng JF Olsen A Lucas S Elkin C Uberbacher E Frazier M Gibbs RA Muzny DM Scherer SE Bouck JB Sodergren EJ Worley KC Rives CM Gorrell JH Metzker ML Naylor SL Kucherlapati RS Nelson DL Weinstock GM Sakaki Y Fujiyama A Hattori M Yada T Toyoda A Itoh T Kawagoe C Watanabe H Totoki Y Taylor T Weissenbach J Heilig R Saurin W Artiguenave F Brottier P Bruls T Pelletier E Robert C Wincker P Smith DR Doucette-Stamm L Rubenfield M Weinstock K Lee HM Dubois J Rosenthal A Platzer M Nyakatura G Taudien S Rump A Yang H Yu J Wang J Huang G Gu J Hood L Rowen L Madan A Qin S Davis RW Federspiel NA Abola AP Proctor MJ Myers RM Schmutz J Dickson M Grimwood J Cox DR Olson MV Kaul R Raymond C Shimizu N Kawasaki K Minoshima S Evans GA Athanasiou M Schultz R Roe BA Chen F Pan H Ramser J Lehrach H Reinhardt R McCombie WR de la Bastide M Dedhia N Blocker H Hornischer K Nordsiek G Agarwala R Aravind L Bailey JA Bateman A Batzoglou S Birney E Bork P Brown DG Burge CB Cerutti L Chen HC Church D Clamp M Copley RR Doerks T Eddy SR Eichler EE Furey TS Galagan J Gilbert JG Harmon C Hayashizaki Y Haussler D Hermjakob H Hokamp K Jang W Johnson LS Jones TA Kasif S Kaspryzk A Kennedy S Kent WJ Kitts P Koonin EV Korf I Kulp D Lancet D Lowe TM McLysaght A Mikkelsen T Moran JV Mulder N Pollara VJ Ponting CP Schuler G Schultz J Slater G Smit AF Stupka E Szustakowski J Thierry-Mieg D Thierry-Mieg J Wagner L Wallis J Wheeler R Williams A Wolf YI Wolfe KH Yang SP Yeh RF Collins F Guyer MS Peterson J Felsenfeld A Wetterstrand KA Patrinos A Morgan MJ de Jong P Catanese JJ Osoegawa K Shizuya H Choi S Chen YJ Initial sequencing and analysis of the human genome Nature 2001, 409(6822):860-921. 10.1038/35057062 11237011
3. de Parseval N Lazar V Casella JF Benit L Heidmann T Survey of human genes of retroviral origin: Identification and transcriptome of the genes with coding capacity for complete envelope proteins J Virol 2003, 77(19):10414-10422. 228468 12970426 10.1128/JVI.77.19.10414-10422.2003
4. Blaise S de Parseval N Benit L Heidmann T Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution Proc Natl Acad Sci U S A 2003, 100(22):13013-13018. 240736 14557543 10.1073/pnas.2132646100
5. Blond JL Lavillette D Cheynet V Bouton O Oriol G Chapel-Fernandes S Mandrand B Mallet F Cosset FL An envelope glycoprotein of the human endogenous retrovirus HERV-W is expressed in the human placenta and fuses cells expressing the type D mammalian retrovirus receptor J Virol 2000, 74(7):3321-3329. 111833 10708449 10.1128/JVI.74.7.3321-3329.2000
6. Mi S Lee X Li X Veldman GM Finnerty H Racie L LaVallie E Tang XY Edouard P Howes S Keith JC Jr. McCoy JM Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis Nature 2000, 403(6771):785-789. 10.1038/35001608 10693809
7. Bernischke K Kaufmann P Pathology of the human placenta 4th edition New-York Springer 2000.
8. Alsat E Mirlesse V Fondacci C Dodeur M Evain-Brion D Parathyroid hormone increases epidermal growth factor receptors in cultured human trophoblastic cells from early and term placenta J Clin Endocrinol Metab 1991, 73(2):288-295. 1856260
9. Kliman HJ Nestler JE Sermasi E Sanger JM Strauss JF 3rd Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae Endocrinology 1986, 118(4):1567-1582. 3512258
10. Frendo JL Vidaud M Guibourdenche J Luton D Muller F Bellet D Giovagrandi Y Tarrade A Porquet D Blot P Evain-Brion D Defect of villous cytotrophoblast differentiation into syncytiotrophoblast in Down's syndrome J Clin Endocrinol Metab 2000, 85(10):3700-3707. 10.1210/ jc.85.10.3700 11061527
11. Pidoux G Guibourdenche J Frendo JL Gerbaud P Conti M Luton D Muller F Evain-Brion D Impact of trisomy 21 on human trophoblast behaviour and hormonal function Placenta 2004, 25(Suppl A):S79-84. 10.1016/ j.placenta.2004.01.007 15033312
12. Frendo JL Guibourdenche J Pidoux G Vidaud M Luton D Giovangrandi Y Porquet D Muller F Evain-Brion D Trophoblast production of a weakly bioactive human chorionic gonadotropin in trisomy 21-affected pregnancy J Clin Endocrinol Metab 2004, 89(2):727-732. 10.1210/jc.2003-030668 14764788
13. Pidoux G Gerbaud P Marpeau O Guibourdenche J Ferreira F Badet J Evain-Brion D Frendo JL Human placental development is impaired by abnormal hCG signaling in trisomy 21 pregnancies Endocrinology 2007. 17690166
14. Frendo JL Cronier L Bertin G Guibourdenche J Vidaud M Evain-Brion D Malassine A Involvement of connexin 43 in human trophoblast cell fusion and differentiation J Cell Sci 2003, 116(Pt 16):3413-3421. 10.1242/ jcs.00648 12840075
15. Malassine A Handschuh K Tsatsaris V Gerbaud P Cheynet V Oriol G Mallet F Evain-Brion D Expression of HERV-W Env glycoprotein (syncytin) in the extravillous trophoblast of first trimester human placenta Placenta 2005, 26(7):556-562. 10.1016/j.placenta.2004.09.002 15993705
16. Muir A Lever AM Moffett A Human endogenous retrovirus-W envelope (syncytin) is expressed in both villous and extravillous trophoblast populations J Gen Virol 2006, 87(Pt 7):2067-2071. 10.1099/vir.0.81412-0 16760410
17. Frendo JL Olivier D Cheynet V Blond JL Bouton O Vidaud M Rabreau M Evain-Brion D Mallet F Direct involvement of HERV-W Env glycoprotein in human trophoblast cell fusion and differentiation Mol Cell Biol 2003, 23(10):3566-3574. 164757 12724415 10.1128/MCB.23.10.3566-3574.2003
18. Malassine A Blaise S Handschuh K Lalucque H Dupressoir A Evain-Brion D Heidmann T Expression of the Fusogenic HERV-FRD Env Glycoprotein (Syncytin 2) in Human Placenta is Restricted to Villous Cytotrophoblastic Cells Placenta 2007, 28(2-3):185-191. 10.1016/ j.placenta.2006.03.001 16714059
19. Harris JR Placental endogenous retrovirus (ERV): Structural, functional, and evolutionary significance Bioessays 1998, 20(4):307-316. 10.1002/ (SICI)1521-1878(199804)20:4<307::AID-BIES7>3.0.CO;2-M 9619102
20. Lin L Xu B Rote NS Expression of endogenous retrovirus ERV-3 induces differentiation in BeWo, a choriocarcinoma model of human placental trophoblast Placenta 1999, 20(1):109-118. 10.1053/plac.1998.0337 9950152
21. Lin L Xu B Rote NS The cellular mechanism by which the human endogenous retrovirus ERV-3 env gene affects proliferation and differentiation in a human placental trophoblast model, BeWo Placenta 2000, 21(1):73-78. 10.1053/plac.1999.0443 10692254
22. de Parseval N Heidmann T Physiological knockout of the envelope gene of the single-copy ERV-3 human endogenous retrovirus in a fraction of the Caucasian population J Virol 1998, 72(4):3442-3445. 109847 9525678
23. Mori M Ishikawa G Luo SS Mishima T Goto T Robinson JM Matsubara S Takeshita T Kataoka H Takizawa T The cytotrophoblast layer of human chorionic villi becomes thinner but maintains its structural integrity during gestation Biol Reprod 2007, 76(1):164-172. 10.1095/ biolreprod.106.056127 17035639
24. Oberweis D Gillerot Y Koulischer L Hustin J Philippe E [The placenta in trisomy in the last trimester of pregnancy] J Gynecol Obstet Biol Reprod (Paris) 1983, 12(4):345-349. 6226731
25. Roberts L Sebire NJ Fowler D Nicolaides KH Histomorphological features of chorionic villi at 10-14 weeks of gestation in trisomic and chromosomally normal pregnancies Placenta 2000, 21(7):678-683. 10.1053/ plac.2000.0553 10985971
26. Pidoux G Gerbaud P Marpeau O Guibourdenche J Ferreira F Badet J Evain-Brion D Frendo JL Human placental development is impaired by abnormal human chorionic gonadotropin signaling in trisomy 21 pregnancies Endocrinology 2007, 148(11):5403-5413. 10.1210/en.2007-0589 17690166
27. Cheynet V Oriol G Mallet F Identification of the hASCT2-binding domain of the Env ERVWE1/syncytin-1 fusogenic glycoprotein Retrovirology 2006, 3:41. 1524976 16820059 10.1186/1742-4690-3-41
28. Dupressoir A Marceau G Vernochet C Benit L Kanellopoulos C Sapin V Heidmann T Syncytin-A and syncytin-B, two fusogenic placenta-specific murine envelope genes of retroviral origin conserved in Muridae Proc Natl Acad Sci U S A 2005, 102(3):725-730. 545540 15644441 10.1073/ pnas.0406509102
29. Dunlap KA Palmarini M Varela M Burghardt RC Hayashi K Farmer JL Spencer TE Endogenous retroviruses regulate periimplantation placental growth and differentiation Proc Natl Acad Sci U S A 2006, 103(39):14390-14395. 1599973 16980413 10.1073/pnas.0603836103
30. Prudhomme S Bonnaud B Mallet F Endogenous retroviruses and animal reproduction Cytogenet Genome Res 2005, 110(1-4):353-364. 10.1159/ 000084967 16093687
31. Gong R Huang L Shi J Luo K Qiu G Feng H Tien P Xiao G Syncytin-A mediates the formation of syncytiotrophoblast involved in mouse placental development Cell Physiol Biochem 2007, 20(5):517-526. 10.1159/ 000107535 17762178