Solid-phase synthesis of a library based on biphenyl-containing trypsin-like serine protease inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 22, 2009, Pages 6477-6480

  Shi, Shuhao ^a   Zhu, Shirong ^a   Gerritz, Samuel W ^a   Rachwal, Bogumila ^a   Ruan, Zheming ^a   Hutchins, Robert ^a   Kakarla, Ramesh ^a   Sofia, Michael J ^a   Sutton, James ^a   Cheney, Daniel ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Biphenyl; Nanokan; Pinacolboronate; Solid phase library; Trypsin like serine protease inhibitor

Indexed keywords

BIPHENYL; BORONIC ACID DERIVATIVE; SERINE PROTEINASE INHIBITOR; TRIFLUOROMETHANESULFONIC ACID;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID PHASE SYNTHESIS; SUZUKI REACTION;

ASPARTIC ACID; BIPHENYL COMPOUNDS; HIV PROTEASE INHIBITORS; MAST CELLS; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PROTEASE INHIBITORS; PROTEIN CONFORMATION; SERINE; SERINE ENDOPEPTIDASES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 71049168887     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.08.100     Document Type: Article

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