Regular Tai Chi Chuan exercise improves T cell helper function of patients with type 2 diabetes mellitus with an increase in T-bet transcription factor and IL-12 production

British Journal of Sports Medicine

Volumn 43, Issue 11, 2009, Pages 845-850

  Yeh, S H ^a,b   Chuang, H ^c   Lin, L W ^d   Hsiao, C Y ^e   Wang, P W ^c   Liu, R T ^c   Yang, K D ^c  

^a CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

^d DEAKIN UNIVERSITY   (Australia)

^e TZU HUI INSTITUTE OF TECHNOLOGY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

GLIBENCLAMIDE; GLIMEPIRIDE; GLIPIZIDE; GLUCOSE; HEMOGLOBIN A1C; INTERLEUKIN 12; INTERLEUKIN 4; METFORMIN; PIOGLITAZONE; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ARTICLE; BLOOD CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; LYMPHOCYTE FUNCTION; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; TAI CHI; TH1 CELL; TH2 CELL;

BLOOD GLUCOSE; BODY MASS INDEX; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INTERLEUKIN-12; MALE; MIDDLE AGED; T-BOX DOMAIN PROTEINS; T-LYMPHOCYTES, HELPER-INDUCER; TAI JI; TH1 CELLS; TH2 CELLS;

EID: 71049153794     PISSN: 03063674     EISSN: 14730480     Source Type: Journal    
DOI: 10.1136/bjsm.2007.043562     Document Type: Article

References (39)

1. Nieman DC. Current perspective on exercise immunology. Curr Sports Med Rep 2003;2:239-42.
2. Suzuki K, Nakaji S, Yamada M, et al. Systemic inflammatory response to exhaustive exercise: cytokine kinetics. Exerc Immunol Rev 2002;8:6-48.
3. Shore S, Shinkai S, Rhind S, et al. Immune responses to training: how critical is training volume? J Sports Med Phys Fitness 1999;39:1-11.
4. Davis JM, Murphy EA, Brown AS, et al. Effects of moderate exercise and oat beta-glucan on innate immune function and susceptibility to respiratory infection. Am J Physiol Regul Integr Comp Physiol 2004;286:R366-72.
5. Wang C, Collet JP, Lau J. The effect of TCC exercise on health outcomes in patients with chronic conditions: a systematic review. Arch Intern Med 2004;164:493-501. (Pubitemid 38314444)
6. Lu WA, Kuo CD. The effect of Tai Chi Chuan on the autonomic nervous modulation in older persons. Med Sci Sports Exerc 2003;35:1972-6.
7. Cheng MC. Tai Chi Chuan: a simplified method of calisthenics for health and self defense. Berkeley, CA: North Atlantic Book, 1981:32-111.
8. Chan SP, Luk TC, Hong Y. Kinematic and electromyographic analysis of the push movement in tai chi. Br J Sports Med 2003;37:339-344 (Pubitemid 36981030)
9. Li JX, Hong Y, Chan KM. Tai chi: physiological characteristics and beneficial effects on health. Br J Sports Med 2001;35:148-156 (Pubitemid 32973429)
10. Li JX, Hong Y, Chan KM. Effects of long term Tai Chi practice and jogging exercise on muscle strength and endurance in older people. Br J Sports Med 2006;40:50-54 (Pubitemid 43028593)
11. Bloomgarden ZT. Inflammation, atherosclerosis, and aspects of insulin action. Diabetes Care 2005;28:2312-9.
12. Schalkwijk CG, Stehouwer CD. Vascular complications in diabetes mellitus: the role of endothelial dysfunction. Clin Sci (Lond) 2005;109:143-159 (Pubitemid 41117297)
13. Benfield T, Jensen JS, Nordestgaard BG. Influence of diabetes and hyperglycaemia on infectious disease hospitalisation and outcome. Diabetologia 2007;50:549-554 (Pubitemid 46215497)
14. Bashar M, Alcabes P, Rom WN, et al. Increased incidence of multidrug-resistant tuberculosis in diabetic patients on the Bellevue Chest Service, 1987 to 1997. Chest 2001;120:1514-9.
15. Neu I, Rodiek S. Significance of diabetes mellitus in the activation of the varicella zoster virus (authors' translation). MMW Munch Med Wochenschr 1997;119:543-6.
16. Kubeyinje EP. Severity of varicella infection in Saudis with diabetes mellitus: a possible role of acyclovir in treatment. East Afr Med J 1995;72:739-741 (Pubitemid 26333527)
17. Bruunsgaard H. Physical activity and modulation of systemic low-level inflammation. J Leukoc Biol 2005;78:819-835 (Pubitemid 41384398)
18. Peterson AM, Pederson BK: The anti-inflammatory effect of exercise. J Appl Physiol 2005;98:1154-62.
19. Steward KJ. Role of exercise training on cardiovascular disease in persons who have type 2 diabetes and hypertension. Cardiol Clin 2004;22:569-586 (Pubitemid 39389009)
20. Yeh SH, Chuang H, Lin LW, et al. Regular Tai Chi Chuan exercise enhances functional mobility and CD4CD25 regulatory T cells. Br J Sports Med 2006;40:239-243 (Pubitemid 43384741)
21. Yeh SH, Chuang H, Lin LW, et al. Tai Chi Chuan exercise decreases HbA1c level along with increase of regulatory T cells and decrease of cytotoxic T cell population in Type 2 diabetic patients. Diabetes Care 2007;30:716-718 (Pubitemid 46354359)
22. Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996;383:787-93.
23. Taylor JJ, Mohrs M, Pearce EJ. Regulatory T cell responses develop in parallel to Th responses and control the magnitude and phenotype of the Th effector population. J Immunol 2006;176:5839-47.
24. Yu HR, Chen RF, Hong KC, et al. IL-12-independent Th1 polarization in human mononuclear cells infected with varicella-zoster virus. Eur J Immunol 2005;35:3664-72.
25. Chen RF, Liu JW, Yeh WT, et al. Altered T helper 1 reaction but not increase of virus load in patients with dengue hemorrhagic fever. FEMS Immunol Med Microbiol 2005;44:43-50.
26. Suzuki K, Nakaji S, Kurakake S, et al. Exhaustive exercise and type-1/type-2 cytokine balance with special focus on interleukin-12 p40/p70. Exerc Immunol Rev 2003;9:48-57.
27. Shore S, Shinkai S, Rhind S, et al. Immune responses to training: how critical is training volume? J Sports Med Phys Fitness 1999;39:1-11.
28. Sothern MS, Loftin M, Suskind RM, et al. The health benefits of physical activity in children and adolescents: implications for chronic disease prevention. Eur J Pediatr 1999;158:271-274 (Pubitemid 29183699)
29. Murphy EA, Davis JM, Brown AS, et al. Effects of moderate exercise and oat beta-glucan on lung tumor metastases and macrophage antitumor cytotoxicity. J Appl Physiol 2004;97:955-9.
30. Bharat A, Fields RC, Trulock EP, et al. Induction of IL-10 suppressors in lung transplant patients by CD4+25+ regulatory T cells through CTLA-4 signaling. J Immunol 2006;177:5631-5638 (Pubitemid 44527638)
31. Miyazaki T, Ishikawa T, Nakata A, et al. Association between perceived social support and Th1 dominance. Biol Psychol 2005;70:30-37 (Pubitemid 40982646)
32. Kimata H. Kissing selectively decreases allergen-specific IgE production in atopic patients. J Psychosom Res 2006;60:545-7.
33. Hashizume H, Horibe T, Ohshima A, et al. Anxiety accelerates T-helper 2-tilted immune responses in patients with atopic dermatitis. Br J Dermatol 2005;152:1161-1164 (Pubitemid 40933412)
34. Fritz T, Kramer DK, Karlsson HK, et al. Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients. Diabetes Metab Res Rev 2006;22:492-498 (Pubitemid 44774054)
35. Ratner RE. The diabetes prevention program. An update on the diabetes prevention program. Endocr Pract 2006;12(Suppl 1):20-4.
36. Nielsen PJ, Hafdahl AR, Conn VS, et al. Meta-analysis of the effect of exercise interventions on fitness outcomes among adults with type 1 and type 2 diabetes. Diabetes Res Clin Pract 2006;74:111-20.
37. Kempf AK, Rose B, Herder C, et al. The metabolic syndrome sensitizes leukocytes for glucose-induced immune gene expression. J Mol Med 2007;85:389-396 (Pubitemid 46452255)
38. Kempf AK, Rose B, Herder C, et al. Inflammation in metabolic syndrome and type 2 diabetes: impact of dietary glucose. Ann NY Acad Sci 2006;1084:30-38 (Pubitemid 47091946)
39. Song R, Lee EO, Lam P, et al. Effects of Tai Chi exercise on pain, balance, muscle strength, and perceived difficulties in physical functioning in older women with osteoarthritis: a randomized clinical trial. J Rheumatol 2003;30:2039-2044 (Pubitemid 37075559)