Anxiety accelerates T-helper 2-tilted immune responses in patients with atopic dermatitis

British Journal of Dermatology

Volumn 152, Issue 6, 2005, Pages 1161-1164

  Hashizume, Hideo ^a   Horibe, T ^a   Ohshima, A ^a   Ito, T ^a   Yagi, H ^a   Takigawa, M ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Anxiety; Atopic dermatitis; IgE; Stress; T helper 2

Indexed keywords

ANTIHISTAMINIC AGENT; CORTICOSTEROID; EMOLLIENT AGENT; IMMUNOGLOBULIN E; TACROLIMUS;

ADOLESCENT; ADULT; ANXIETY; ARTICLE; ATOPIC DERMATITIS; ATOPY; CELL COUNT; CONTROLLED STUDY; EOSINOPHIL; FEMALE; HELPER CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; IMMUNOPATHOGENESIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PRURITUS; SCHOOL CHILD; SKIN MANIFESTATION; STATE TRAIT ANXIETY INVENTORY; STRESS; TH1 CELL; TH2 CELL; VISUAL ANALOG SCALE;

ADOLESCENT; ADULT; ANXIETY; ANXIETY DISORDERS; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; DERMATITIS, ATOPIC; EOSINOPHILIA; FEMALE; HUMANS; IMMUNOGLOBULIN E; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; STATISTICS, NONPARAMETRIC; TH1 CELLS; TH2 CELLS; URTICARIA;

EID: 21644446887     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2005.06449.x     Document Type: Article

References (19)

1. Leung DY, Bieber T. Atopic dermatitis. Lancet 2003; 361:151-60.
2. Laughter D, Istvan JA, Tofte SJ et al. The prevalence of atopic dermatitis in Oregon schoolchildren. J Am Acad Dermatol 2000; 43:649-55.
3. Gupta MA, Gupta AK. Depression and suicidal ideation in dermatology patients with acne, alopecia areata, atopic dermatitis and psoriasis. Br J Dermatol 1998; 139:846-50.
4. Howlett S. Emotional dysfunction, child-family relationships and childhood atopic dermatitis. Br J Dermatol 1999; 140:381-4.
5. Linnet J, Jemec GB. An assessment of anxiety and dermatology life quality in patients with atopic dermatitis. Br J Dermatol 1999; 140:268-72.
6. Linnet J, Jemec GB. Anxiety level and severity of skin condition predicts outcome of psychotherapy in atopic dermatitis patients. Int J Dermatol 2001; 40:632-6.
7. Kiecolt-Glaser JK. Norman Cousins Memorial Lecture 1998. Stress, personal relationships, and immune function: health implications. Brain Behav Immun 1999; 13:61-72.
8. Buske-Kirschbaum A, Geiben A, Hellhammer D. Psychobiological aspects of atopic dermatitis: in overview. Psychother Psychosom 2001; 70:6-16.
9. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol (Stockh) 1980; 92 (Suppl.):44-7.
10. Kunz B, Oranje AP, Labreze L et al. Clinical validation and guidelines for die SCORAD index: consensus report of die European Task Force on Atopic Dermatitis. Dermatology 1997; 195:10-19.
11. Iwata N, Mishima N, Shimizu T et al. The Japanese adaptation of the STAI Form Y in Japanese working adults-the presence or absence of anxiety. Ind Health 1998; 36:8-13.
12. Rostaing L, Tkaczuk J, Durand M et al. Kinetics of intracytoplasmic Th1 and Th2 cytokine production assessed by flow cytometry following in vitro activation of peripheral blood mononuclear cells. Cytometry 1999; 35:318-28.
13. Del Prete G. Human Th1 and Th2 lymphocytes: their role in the pathophysiology of atopy. Allergy 1992; 47:450-5.
14. Tausk FA, Nousari H. Stress and the skin. Arch Dermatol 2001; 137:78-82.
15. Scheich G, Florin I, Rudolph R et al. Personality characteristics and serum IgE level in patients with atopic dermatitis. J Psychosom Res 1993; 37:637-42.
16. Paik IH, Toh KY, Lee C et al. Psychological stress may induce increased humoral and decreased cellular immunity. Behav Med 2000; 26:139-41.
17. Buske-Kirschbaum A, Gierens A, Hollig H et al. Stress-induced immunomodulation is altered in patients with atopic dermatitis. J Neuroimmunol 2002; 129:161-7.
18. Schmid-Ott G, Jaeger B, Adamek C et al. Levels of circulating CD8(+) T lymphocytes, natural killer cells, and eosinophils increase upon acute psychosocial stress in patients with atopic dermatitis. J Allergy Clin Immunol 2001; 107:171-7.
19. Ginsburg IH, Prystowsky JH, Kornfeld DS et al. Role of emotional factors in adults with atopic dermatitis. Int J Dermatol 1993; 32:656-60.