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Volumn 21, Issue 6, 2009, Pages 300-306

Hoodia: A herb used in South African traditional medicine - A potential cure for overweight? Pharmacognostic review of history, composition, health-related claims, scientific evidence and intellectual property rights

Author keywords

Appetite suppression; Hoodia; Pharmacognosy; Quality control; Safety; San

Indexed keywords

DRUG METABOLIZING ENZYME; GLYCOSIDE; HERBACEOUS AGENT; P57AS3 GLYCOSIDE; UNCLASSIFIED DRUG;

EID: 71049144961     PISSN: 10150684     EISSN: None     Source Type: Journal    
DOI: 10.1159/000291013     Document Type: Review
Times cited : (17)

References (45)
  • 1
    • 53449091761 scopus 로고    scopus 로고
    • A review of Khoi-San and Cape Dutch medical ethnobotany
    • Van Wyk BE: A review of Khoi-San and Cape Dutch medical ethnobotany. J Ethnopharmacol 2008;119:331-341.
    • (2008) J Ethnopharmacol , vol.119 , pp. 331-341
    • Van Wyk, B.E.1
  • 2
    • 38749097401 scopus 로고    scopus 로고
    • Traditional Knowledge and Patenting: The Experience of the Neemfungicide and the Hoodia Cases
    • Dolder F: Traditional Knowledge and Patenting: The Experience of the Neemfungicide and the Hoodia Cases. Biotechnology Law Report 2007;26(6):583-590.
    • (2007) Biotechnology Law Report , vol.26 , Issue.6 , pp. 583-590
    • Dolder, F.1
  • 4
    • 33645377400 scopus 로고    scopus 로고
    • Use of Traditional Knowledge of Hoodia Species in the Development of an Appetite Suppressant
    • Wynberg R: Use of Traditional Knowledge of Hoodia Species in the Development of an Appetite Suppressant. The Journal of World Intellectual Property 2004;7(6):851-876.
    • (2004) The Journal of World Intellectual Property , vol.7 , Issue.6 , pp. 851-876
    • Wynberg, R.1
  • 8
    • 0012290293 scopus 로고
    • 2nd edition, Abbey San Encino Press, Pasadena, California
    • White A, Sloan BL: The Stapelieae. Vol III, 2nd edition, Abbey San Encino Press, Pasadena, California, 1937.
    • (1937) The Stapelieae , vol.3
    • White, A.1    Sloan, B.L.2
  • 9
    • 39449123577 scopus 로고    scopus 로고
    • Patenting Neem and Hoodia: Conflicting Decisions Issued by the Opposition Board of the European Patent Office
    • Moyer-Henry K: Patenting Neem and Hoodia: Conflicting Decisions Issued by the Opposition Board of the European Patent Office. Biotechnology Law Report 2008;27(1):1-10.
    • (2008) Biotechnology Law Report , vol.27 , Issue.1 , pp. 1-10
    • Moyer-Henry, K.1
  • 10
    • 34548636672 scopus 로고    scopus 로고
    • Steroidal glycosides, methods for their production and preparation, pharmaceutical compositions containing them, and their use as appetite suppressants
    • patent; W09846243
    • Van Heerden FR, Vleggaar R, Horak RM, Learmonth RA, Maharaj V, Whittal RD: Steroidal glycosides, methods for their production and preparation, pharmaceutical compositions containing them, and their use as appetite suppressants. 1998: patent; W09846243.
    • (1998)
    • Van Heerden, F.R.1    Vleggaar, R.2    Horak, R.M.3    Learmonth, R.A.4    Maharaj, V.5    Whittal, R.D.6
  • 14
    • 71049154544 scopus 로고    scopus 로고
    • available at: accessed June 24th 2009
    • Neutraceuticals World, Braking News, Unilever abandons hoodia project; available at: http://www.nutraceuticalsworld.com/news/2008/11/26 (accessed June 24th 2009).
    • Unilever Abandons Hoodia Project
  • 15
    • 71049127453 scopus 로고    scopus 로고
    • Press release, 12 Dec available at: accessed June 24th 2009
    • Phyotpharm, News, News Releases, Unilever returns rights to Hoodia extract, Press release, 12 Dec 2008; available at: www.phytopharm.com/news/ newsreleases/?id=16553 (accessed June 24th 2009).
    • (2008) Unilever Returns Rights to Hoodia Extract
  • 17
    • 71049182311 scopus 로고    scopus 로고
    • Press release, 20 May available at: accessed June 24th 2009
    • Phyotpharm, News, News Releases, Interim Results for the six months ended 31 March 2009, Press release, 20 May 2009; available at: www.phytopharm.com/ news/newsreleases/?id=17403 (accessed June 24th 2009).
    • (2009) Interim Results for the Six Months Ended 31 March 2009
  • 18
    • 24944486821 scopus 로고    scopus 로고
    • Intellectual Property, Indigenous Knowledge, and Biodiversity
    • Martin G, Vermeylen S: Intellectual Property, Indigenous Knowledge, and Biodiversity. Capitalism Nature Socialism 2005;(16)3:27-48.
    • (2005) Capitalism Nature Socialism , vol.3 , Issue.16 , pp. 27-48
    • Martin, G.1    Vermeylen, S.2
  • 19
    • 33745879141 scopus 로고    scopus 로고
    • Protecting traditional knowledge: The San and hoodia
    • Anonymous
    • Anonymous: Protecting traditional knowledge: the San and hoodia. Bulletin of the World Health Organization 2006;84(5):345.
    • (2006) Bulletin of the World Health Organization , vol.84 , Issue.5 , pp. 345
  • 20
    • 43349104322 scopus 로고    scopus 로고
    • Benefit sharing and access to essential health care: A happy marriage?
    • Schoeder D, Chennells R: Benefit sharing and access to essential health care: a happy marriage? Medicine and Law 2008;27(1):53-69.
    • (2008) Medicine and Law , vol.27 , Issue.1 , pp. 53-69
    • Schoeder, D.1    Chennells, R.2
  • 21
    • 53449088932 scopus 로고    scopus 로고
    • Hoodia gordonii: A natural appetite suppressant
    • Van Heerden FR. Hoodia gordonii: A natural appetite suppressant. J Ethnopharmacol 2008;119:434-437.
    • (2008) J Ethnopharmacol , vol.119 , pp. 434-437
    • Van Heerden, F.R.1
  • 22
    • 0000044142 scopus 로고
    • A revision of Hoodia and Lavrania (Asclepiadaceae-Stapelieae)
    • Bruyns PV: A revision of Hoodia and Lavrania (Asclepiadaceae-Stapelieae). Botanische Jahrbücher 1993;115:145-270.
    • (1993) Botanische Jahrbücher , vol.115 , pp. 145-270
    • Bruyns, P.V.1
  • 24
    • 34547570640 scopus 로고    scopus 로고
    • Indigenous use of Hoodia gordonii and appetite suppression
    • Lee RA, Balick MJ: Indigenous use of Hoodia gordonii and appetite suppression. Explore 2007;3(4):404-406.
    • (2007) Explore , vol.3 , Issue.4 , pp. 404-406
    • Lee, R.A.1    Balick, M.J.2
  • 25
    • 53449092758 scopus 로고    scopus 로고
    • A broad review of commercially important Southern African medicinal plants
    • Van Wyk BE: A broad review of commercially important Southern African medicinal plants. J Ethnopharmacol 2008;119:342-355.
    • (2008) J Ethnopharmacol , vol.119 , pp. 342-355
    • Van Wyk, B.E.1
  • 26
    • 0345637420 scopus 로고    scopus 로고
    • Southern African Biodiversity Network Report No.14 SABONET, Pretoria
    • Golding J: Southern African Plant Red Data Lists. Southern African Biodiversity Network Report No.14 2002: SABONET, Pretoria.
    • (2002) Southern African Plant Red Data Lists
    • Golding, J.1
  • 27
    • 84940277008 scopus 로고    scopus 로고
    • available at: accessed June 23rd 2009
    • CITES species database, Hoodia gordonii; available at: www.cites.org/eng/resources/ species.html (accessed June 23rd 2009).
    • CITES Species Database, Hoodia Gordonii
  • 29
    • 71049193916 scopus 로고    scopus 로고
    • Steroidal glycosides or plant extracts for treatment of gastric acid secretion damage
    • patent; EP1099444
    • Horak RM, Maharaj V, Hakkinen J: Steroidal glycosides or plant extracts for treatment of gastric acid secretion damage. 2001: patent; EP1099444.
    • (2001)
    • Horak, R.M.1    Maharaj, V.2    Hakkinen, J.3
  • 30
    • 34248510066 scopus 로고    scopus 로고
    • Steroidal glycosides from Hoodia gordonii
    • Dall'Acqua S, Innencenti G: Steroidal glycosides from Hoodia gordonii. Steroids 2007;72:559-568.
    • (2007) Steroids , vol.72 , pp. 559-568
    • Dall'Acqua, S.1    Innencenti, G.2
  • 31
    • 34248554412 scopus 로고    scopus 로고
    • New oxypregnane glycosides from appetite suppressant herbal supplement Hoodia gordonii
    • DOI 10.1016/j.steroids.2007.03.003, PII S0039128X07000475
    • Pawar RS, Shukla YJ. Khan SI, Avula B, Khan IA. New oxypregnane glycosides from appetite suppressant herbal supplement Hoodia grodonii. Steroids 2007;72:524-534. (Pubitemid 46764789)
    • (2007) Steroids , vol.72 , Issue.6-7 , pp. 524-534
    • Pawar, R.S.1    Shukla, Y.J.2    Khan, S.I.3    Avula, B.4    Khan, I.A.5
  • 32
    • 34548631798 scopus 로고    scopus 로고
    • New calogenin glycosides from Hoodia gordonii
    • DOI 10.1016/j.steroids.2007.07.010, PII S0039128X07001237
    • Pawar RS, Shukla YJ, Khan IA. New calogenin glycosides from Hoodia gordonii. Steroids 2007;72:881-891. (Pubitemid 47410070)
    • (2007) Steroids , vol.72 , Issue.13 , pp. 881-891
    • Pawar, R.S.1    Shukla, Y.J.2    Khan, I.A.3
  • 33
    • 71049166387 scopus 로고    scopus 로고
    • Appetite suppressant compositions
    • patent; WO 2007096239
    • Abrahamse SL, Povey KF, Rees DD. Appetite suppressant compositions. 2007: patent; WO 2007096239.
    • (2007)
    • Abrahamse, S.L.1    Povey, K.F.2    Rees, D.D.3
  • 35
    • 50249184644 scopus 로고    scopus 로고
    • Identification and structural characterization of steroidal glycosides in Hoodia gordonii by ion-trap tandem mass spectrometry and liquid chromatography coupled with electrospray ionization time-of-flight mass spectrometry
    • Avula B, Wnag YH, Pawar RS, Shukla YJ, Smillie TJ, Khan IA. Identification and structural characterization of steroidal glycosides in Hoodia gordonii by ion-trap tandem mass spectrometry and liquid chromatography coupled with electrospray ionization time-of-flight mass spectrometry. Rapid Com Mass Spec 2008;22:2587-2596.
    • (2008) Rapid Com Mass Spec , vol.22 , pp. 2587-2596
    • Avula, B.1    Wnag, Y.H.2    Pawar, R.S.3    Shukla, Y.J.4    Smillie, T.J.5    Khan, I.A.6
  • 37
    • 53049106728 scopus 로고    scopus 로고
    • A rapid method for chemical fingerprint analysis of Hoodia species, related genera, and dietary supplements using UPLC-UV-MS
    • Avula B, Wang YH, Pawar RS, Shukla YJ, Smillie TJ, Khan IA: A rapid method for chemical fingerprint analysis of Hoodia species, related genera, and dietary supplements using UPLC-UV-MS. J Pharm Biomed Anal 2008;48:722-731.
    • (2008) J Pharm Biomed Anal , vol.48 , pp. 722-731
    • Avula, B.1    Wang, Y.H.2    Pawar, R.S.3    Shukla, Y.J.4    Smillie, T.J.5    Khan, I.A.6
  • 38
    • 38149093104 scopus 로고    scopus 로고
    • Chemical Fingerprinting of Hoodia Species and Related Genera: Chemical Analysis of Oxypregnane Glycosides Using High-Performance Liquid Chromatography with UV Detection in Hoodia gordonii
    • Avula B, Wang YH, Pawar RS, Shukla YJ, Khan IA: Chemical Fingerprinting of Hoodia Species and Related Genera: Chemical Analysis of Oxypregnane Glycosides Using High-Performance Liquid Chromatography with UV Detection in Hoodia gordonii. Journal of AOAC International 2007;90(6): 1526-1531.
    • (2007) Journal of AOAC International , vol.90 , Issue.6 , pp. 1526-1531
    • Avula, B.1    Wang, Y.H.2    Pawar, R.S.3    Shukla, Y.J.4    Khan, I.A.5
  • 39
    • 33750711741 scopus 로고    scopus 로고
    • Determination of the Appetite Suppressant P57 in Hoodia gordonii Plant Extracts and Dietary Supplements by Liquid Chromatography/Electrospray Ionization Mass Spectrometry (LC-MSD-TOF) and LC-UV Methods
    • Avula B, Wang YH, Pawar RS, Shukla YJ, Schaneberg B, Khan IA: Determination of the Appetite Suppressant P57 in Hoodia gordonii Plant Extracts and Dietary Supplements by Liquid Chromatography/Electrospray Ionization Mass Spectrometry (LC-MSD-TOF) and LC-UV Methods. Journal of AOAC International 2006;89(3):606-611.
    • (2006) Journal of AOAC International , vol.89 , Issue.3 , pp. 606-611
    • Avula, B.1    Wang, Y.H.2    Pawar, R.S.3    Shukla, Y.J.4    Schaneberg, B.5    Khan, I.A.6
  • 40
    • 43649108474 scopus 로고    scopus 로고
    • Quantification of appetite suppressing steroid glycosides from Hoodia gordonii in dried plant material, purified extracts and food products using HPLC-UF and HPLC-MS methods
    • Janssen HG, Swindells C, Gunning P, Wang W, Grün C, Mahabir K, Maharaj VJ, Apps PJ: Quantification of appetite suppressing steroid glycosides from Hoodia gordonii in dried plant material, purified extracts and food products using HPLC-UF and HPLC-MS methods. Anal Chim Act 2008;617;200-207.
    • (2008) Anal Chim Act , vol.617 , pp. 200-207
    • Janssen, H.G.1    Swindells, C.2    Gunning, P.3    Wang, W.4    Grün, C.5    Mahabir, K.6    Maharaj, V.J.7    Apps, P.J.8
  • 41
    • 50649101755 scopus 로고    scopus 로고
    • In Vitro Metabolic Stability and Intestinal Transport of P57AS3 (P57) from Hoodia gordonii and its Interaction with Drug Metabolizing Enzymes
    • Madgula VLM, Avula B., Pawar RS, Shukla YJ, Khan IA, Walker LA, Khan SI: In Vitro Metabolic Stability and Intestinal Transport of P57AS3 (P57) from Hoodia gordonii and its Interaction with Drug Metabolizing Enzymes. Planta Med 2008;74:1269-1275.
    • (2008) Planta Med , vol.74 , pp. 1269-1275
    • Madgula, V.L.M.1    Avula, B.2    Pawar, R.S.3    Shukla, Y.J.4    Khan, I.A.5    Walker, L.A.6    Khan, S.I.7
  • 42
    • 4143129845 scopus 로고    scopus 로고
    • Increased ATP content/ production in the hypothalamus may be a signal for energy-sensing of satiety: Studies of the anorectic mechanism of a plant steroidal glycoside
    • MacLean DB, Luo LG: Increased ATP content/ production in the hypothalamus may be a signal for energy-sensing of satiety: studies of the anorectic mechanism of a plant steroidal glycoside. Brain Res 2004;1020:1-11.
    • (2004) Brain Res , vol.1020 , pp. 1-11
    • MacLean, D.B.1    Luo, L.G.2
  • 45
    • 71049140892 scopus 로고    scopus 로고
    • Hoodia gordonii
    • Eloff JN, Brendler T, Gurib-Fakim A, Phillips LD (Eds.) Association for African Medicinal Plants Standards (AAMPS), Reduit, Mauritius (in press)
    • Van Wyk BE. Hoodia gordonii. In: Eloff JN, Brendler T, Gurib-Fakim A, Phillips LD (Eds.). The African Herbal Pharmacopoeia. Association for African Medicinal Plants Standards (AAMPS), Reduit, Mauritius (in press).
    • The African Herbal Pharmacopoeia
    • Van Wyk, B.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.