Desmocollin 3-mediated binding is crucial for keratinocyte cohesion and is impaired in pemphigus

Journal of Biological Chemistry

Volumn 284, Issue 44, 2009, Pages 30556-30564

  Spindler, Volker ^a   Heupel, Wolfgang Moritz ^a   Efthymiadis, Athina ^a   Schmidt, Enno ^b   Eming, Rüdiger ^c   Rankl, Christian ^d   Hinterdorfer, Peter ^d   Müller, Thomas ^a   Drenckhahn, Detlev ^a   Waschke, Jens ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d JOHANNES KEPLER UNIVERSITY LINZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

AFM; AUTOANTIBODIES; CELL SURFACES; EXTRACELLULAR DOMAINS; HUMAN SKIN; INTERCELLULAR ADHESION; KERATINOCYTES; LASER TWEEZERS; SINGLE MOLECULE; TRANS-MEMBRANE PROTEINS;

ADHESION; ANTIGENS; CELL MEMBRANES; MONOCLONAL ANTIBODIES; SKIN;

ATOMIC FORCE MICROSCOPY;

DESMOCOLLIN; DESMOCOLLIN 3; DESMOGLEIN 3; UNCLASSIFIED DRUG;

ARTICLE; ATOMIC FORCE MICROSCOPY; BLISTER; CELL ADHESION; CELL CULTURE; CELL SURFACE; CONTROLLED STUDY; HUMAN; HUMAN CELL; KERATINOCYTE; PATHOGENESIS; PEMPHIGUS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION;

ANTIBODIES, MONOCLONAL; AUTOANTIBODIES; CELL ADHESION; CELLS, CULTURED; DESMOCOLLINS; DESMOGLEIN 1; HUMANS; KERATINOCYTES; MICROSCOPY, ATOMIC FORCE; OPTICAL TWEEZERS; PEMPHIGUS; PROTEIN BINDING;

EID: 71049116456     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.024810     Document Type: Article

References (39)

1. Waschke, J. (2008) Histochem. Cell Biol. 130, 21-54
2. Kottke, M. D., Delva, E., and Kowalczyk, A. P. (2006) J. Cell Sci. 119, 797-806
3. Heupel, W. M., Müller, T., Efthymiadis, A., Schmidt, E., Drenckhahn, D., and Waschke, J. (2009) J. Biol. Chem. 284, 8589-8595
4. Tsunoda, K., Ota, T., Aoki, M., Yamada, T., Nagai, T., Nakagawa, T., Koyasu, S., Nishikawa, T., and Amagai, M. (2003) J. Immunol. 170, 2170-2178
5. Posy, S., Shapiro, L., and Honig, B. (2008) J. Mol. Biol. 378, 954-968
6. Getsios, S., Huen, A. C., and Green, K. J. (2004) Nat. Rev. Mol. Cell Biol. 5, 271-281
7. Nuber, U. A., Schäfer, S., Stehr, S., Rackwitz, H. R., and Franke, W. W. (1996) Eur. J. Cell Biol. 71, 1-13
8. Mahoney, M. G., Hu, Y., Brennan, D., Bazzi, H., Christiano, A. M., and Wahl, J. K., 3rd (2006) Exp. Dermatol. 15, 101-109
9. Garrod, D., and Chidgey, M. (2008) Biochim. Biophys. Acta 1778, 572-587
10. Chen, J., Den, Z., and Koch, P. J. (2008) J. Cell Sci. 121, 2844-2849
11. Stanley, J. R., and Amagai, M. (2006) N. Engl. J. Med. 355, 1800-1810
12. Hisamatsu, Y., Amagai, M., Garrod, D. R., Kanzaki, T., and Hashimoto, T. (2004) Br. J. Dermatol. 151, 73-83
13. Spindler, V., Drenckhahn, D., Zillikens, D., and Waschke, J. (2007) Am. J. Pathol. 171, 906-916
14. Gotsch, U., Borges, E., Bosse, R., Böggemeyer, E., Simon, M., Mossmann, H., and Vestweber, D. (1997) J. Cell Sci. 110, 583-588
15. Heupel, W. M., Zillikens, D., Drenckhahn, D., and Waschke, J. (2008) J. Immunol. 181, 1825-1834
16. Müller, R., Heber, B., Hashimoto, T., Messer, G., Müllegger, R., Niedermeier, A., and Hertl, M. (2009) Clin. Exp. Dermatol., in press
17. Waschke, J., Bruggeman, P., Baumgartner, W., Zillikens, D., and Drenckhahn, D. (2005) J. Clin. Invest. 115, 3157-3165
18. Heupel, W. M., Baumgartner, W., Laymann, B., Drenckhahn, D., and Golenhofen, N. (2008) Mol. Cell. Neurosci. 37, 548-558
19. Ebner, A., Wildling, L., Kamruzzahan, A. S., Rankl, C., Wruss, J., Hahn, C. D., Holzl, M., Zhu, R., Kienberger, F., Blaas, D., Hinterdorfer, P., and Gruber, H. J. (2007) Bioconjugate Chem. 18, 1176-1184
20. Schmidt, E., Gutberlet, J., Siegmund, D., Berg, D., Wajant, H., and Waschke, J. (2009) Am. J. Physiol. Cell Physiol. 296, C162-C172
21. Waschke, J., Spindler, V., Bruggeman, P., Zillikens, D., Schmidt, G., and Drenckhahn, D. (2006) J. Cell Biol. 175, 721-727
22. Sharma, P. M., Choi, E. J., Kuroda, K., Hachiya, T., Ishii, K., and Payne, A. S. (2009) J. Invest. Dermatol. 129, 2309-2312
23. Yokouchi, M., Saleh, M. A., Kuroda, K., Hachiya, T., Stanley, J. R., Amagai, M., and Ishii, K. (2009) J. Invest. Dermatol. 129, 2156-2166
24. Waschke, J., Menendez-Castro, C., Bruggeman, P., Koob, R., Amagai, M., Gruber, H. J., Drenckhahn, D., and Baumgartner, W. (2007) J. Membr. Biol. 216, 83-92
25. Bell, G. I. (1978) Science 200, 618-627
26. Koch, P. J., Mahoney, M. G., Ishikawa, H., Pulkkinen, L., Uitto, J., Shultz, L., Murphy, G. F., Whitaker-Menezes, D., and Stanley, J. R. (1997) J. Cell Biol. 137, 1091-1102
27. Syed, S. E., Trinnaman, B., Martin, S., Major, S., Hutchinson, J., and Magee, A. I. (2002) Biochem. J. 362, 317-327
28. Marcozzi, C., Burdett, I. D., Buxton, R. S., and Magee, A. I. (1998) J. Cell Sci. 111, 495-509
29. Amagai, M., Kàrpàti, S., Klaus-Kovtun, V., Udey, M. C., and Stanley, J. R. (1994) J. Invest. Dermatol. 103, 609-615
30. Baumgartner, W., Hinterdorfer, P., Ness, W., Raab, A., Vestweber, D., Schindler, H., and Drenckhahn, D. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 4005-4010
31. Baumgartner, W., Golenhofen, N., Grundhöfer, N., Wiegand, J., and Drenckhahn, D. (2003) J. Neurosci. 23, 11008-11014
32. Baumgartner, W., Wendeler, M. W., Weth, A., Koob, R., Drenckhahn, D., and Gessner, R. (2008) J. Mol. Biol. 378, 44-54
33. Perret, E., Benoliel, A. M., Nassoy, P., Pierres, A., Delmas, V., Thiery, J. P., Bongrand, P., and Feracci, H. (2002) EMBO J. 21, 2537-2546
34. Wendeler, M. W., Drenckhahn, D., Gessner, R., and Baumgartner, W. (2007) J. Mol. Biol. 370, 220-230
35. Berkowitz, P., Chua, M., Liu, Z., Diaz, L. A., and Rubenstein, D. S. (2008) Am. J. Pathol. 173, 1628-1636
36. Berkowitz, P., Diaz, L. A., Hall, R. P., and Rubenstein, D. S. (2008) J. Invest. Dermatol. 128, 738-740
37. Berkowitz, P., Hu, P., Liu, Z., Diaz, L. A., Enghild, J. J., Chua, M. P., and Rubenstein, D. S. (2005) J. Biol. Chem. 280, 23778-23784
38. Berkowitz, P., Hu, P., Warren, S., Liu, Z., Diaz, L. A., and Rubenstein, D. S. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 12855-12860
39. Bolling, M. C., Mekkes, J. R., Goldschmidt, W. F., van Noesel, C. J., Jonkman, M. F., and Pas, H. H. (2007) Br. J. Dermatol. 157, 168-173