Peptides targeting the desmoglein 3 adhesive interface prevent autoantibody-induced acantholysis in pemphigus

Journal of Biological Chemistry

Volumn 284, Issue 13, 2009, Pages 8589-8595

  Heupel, Wolfgang Moritz ^a   M'sduller, Thomas ^a   Efthymiadis, Athina ^a   Schmidt, Enno ^a   Drenckhahn, Detlev ^a   Waschke, Jens ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIVE INTERFACES; AUTOANTIBODIES; CELL-BASED; CELLULAR SIGNALING; IN-CELL; KERATINOCYTES; LASER TWEEZERS; PEMPHIGUS VULGARIS; PEPTIDOMIMETICS; SINGLE MOLECULE EXPERIMENTS;

ANTIGENS; ATOMIC FORCE MICROSCOPY; ATOMS; PEPTIDES;

AMINES;

AUTOANTIBODY; CADHERIN; DESMOGLEIN 1; DESMOGLEIN 3; IMMUNOGLOBULIN G; SYNTHETIC PEPTIDE; TANDEM PEPTIDE; UNCLASSIFIED DRUG;

ACANTHOLYSIS; AMINO ACID SEQUENCE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL FREE SYSTEM; CHEMICAL BOND; CONTROLLED STUDY; DRUG DESIGN; DRUG STRUCTURE; HUMAN; HUMAN CELL; INHIBITION KINETICS; KERATINOCYTE; PATHOGENESIS; PEMPHIGUS VULGARIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING;

ACANTHOLYSIS; AUTOANTIBODIES; CELL LINE; DESMOGLEIN 1; DESMOGLEIN 3; HUMANS; IMMUNOGLOBULIN G; KERATINOCYTES; MODELS, MOLECULAR; PEMPHIGUS; PEPTIDES;

EID: 67649846396     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808813200     Document Type: Article

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