Patterns of desmocollin synthesis in human epithelia: Immunolocalization of desmocollins 1 and 3 in special epithelia and in cultured cells

European Journal of Cell Biology

Volumn 71, Issue 1, 1996, Pages 1-13

  Nuber, Ulrike A ^a   Schäfer, Stephan ^a   Stehr, Sabine ^a   Rackwitz, Hans Richard ^a   Franke, Werner W ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Cadherins; Cell junctions; Desmocollins; Desmogleins; Desmosomes; Thymus

Indexed keywords

CADHERIN; MONOCLONAL ANTIBODY;

ARTICLE; CELL CULTURE; EPITHELIUM; HAIR FOLLICLE; HAIR ROOT; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IN SITU HYBRIDIZATION; PATHOLOGY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; SQUAMOUS CELL CARCINOMA;

MURINAE;

EID: 0029834592     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (58)

1. Amagai, M., V. Klaus-Kovtun, J. R. Stanley: Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion. Cell 67, 869-877 (1991).
2. Arnemann, J., K. H. Sullivan, A. I. Magee, I. A. King, R. S. Buxton: Stratification-related expression of isoforms of the desmosomal cadherins in human epidermis. J. Cell Sci. 104, 741-750 (1993).
3. Bosch F. X., R. E. Leube, T. Achtstätter, R. Moll, W. W. Franke: Expression of simple epithelial type cytokeratins in stratified epithelia as detected by immunolocalization and hybridization in situ. J. Cell Biol. 106, 1635-1648 (1988).
4. Buxton, R. S., P. Cowin, W. W. Franke, D. R. Garrod, K. J. Green, I. A. King, P. J. Koch, A. I. Magee, D. A. Rees, J. R. Stanley, M. S. Steinberg: Nomenclature of the desmosomal cadherins. J. Cell Biol. 121, 481-483 (1993).
5. Colic, M., S. Jovanovic, S. Mitrovic, A. Dujic: Immunohistochemical identification of six cytokeratin-defined subsets of the rat thymic epithelial cells. Thymus 13, 175-185 (1989).
6. Collin, C., R. Moll, S. Kubicka, J.-P. Ouhayoun, W. W. Franke: Characterization of human cytokeratin 2, an epidermal cytoskeletal protein synthesized late during differentiation. Exp. Cell Res. 202, 132-141 (1992).
7. Collin, C., J.-P. Ouhayoun, C. Grund, W. W. Franke: Suprabasal marker proteins distinguishing keratinizing squamous epithelia: Cytokeratin 2 polypeptides of oral masticatory epithelium and epidermis are different. Differentiation 51, 137-148 (1992).
8. Collins, J. E., P. K. Legan, T. P. Kenny, J. Macgarvie, J. L. Holton, D. Garrod: Cloning and sequence analysis of desmosomal glycoproteins 2 and 3 (desmocollins): cadherin-like desmosomal adhesion molecules with heterogeneous cytoplasmic domains. J. Cell Biol. 113, 381-391 (1991).
9. Cowin, P., W. W. Franke, C. Grund, H.-P. Kapprell, J. Kartenbeck: The desmosome-intermediate filament complex. In: G. M. Edelman, J.-P. Thiery (eds.): The Cell in Contact. pp. 427-460. John Wiley & Sons. New York 1985.
10. Cowin, P., H.-P. Kapprell, W. W. Franke: The complement of desmosomal plaque proteins in different cell types. J. Cell Biol. 101, 1442-1454 (1985).
11. Demlehner, M., S. Schäfer, C. Grund, W. W. Franke: Continual assembly of half-desmosomal structures in the absence of cell contacts and their frustrated endocytosis: a coordinated Sisyphus cycle. J. Cell Biol. 131, 745-760 (1995).
12. Dervan, P. A., L. G. Gilmartin, P. G. Johnston, D. N. Carney: Desmosomal plaque proteins are preserved in all grades of breast cancer. An immunohistochemical study utilizing monoclonal antibodies to desmoplakin. Am. J. Surg. Pathol. 12, 855-860 (1988).
13. Dmochowski, M., T. Hashimoto, M. A. J. Chidgey, K. K. M. Yue, R. W. Wilkinson, T. Nishikawa, D. R. Garrod: Demonstration of antibodies to bovine desmocollin isoforms in certain pemphigus sera. Br. J. Dermatol. 133, 519-525 (1995).
14. Franke, W. W., B. Appelhans, E. Schmid, C. Freudenstein, M. Osborn, K. Weber: Identification and characterization of epithelial cells in mammalian tissues by immunofluorescence microscopy using antibodies to prekeratin. Differentiation 15, 7-25 (1979).
15. Franke, W. W., E. Schmid, C. Grund, H. Müller, I. Engelbrecht, R. Moll, J. Stadler, E.-D. Jarasch: Antibodies to high molecular weight polypeptides of desmosomes: Specific localization of a class of junctional proteins in cells and tissues. Differentiation 20, 217-241 (1981).
16. Franke, W. W., R. Moll, D. L. Schiller, E. Schmid, J. Kartenbeck, H. Müller: Desmoplakins of epithelial and myocardial desmosomes are immunologically and biochemically related. Differentiation 23, 115-127 (1982).
17. Franke, W. W., R. Moll, H. Müller, E. Schmid, C. Kuhn, R. Krepler, U. Artlieb, H. Denk: Immunocytochemical identification of epithelium-derived human tumors with antibodies to desmosomal plaque proteins. Proc. Natl. Acad. Sci. USA 80, 543-547 (1983).
18. Franke, W. W., U. A. Nuber, S. Schäfer: Desmosomes - dual junctional principles of intra- and supracellular order in epithelial differentiation and tissue formation. Verh. Dtsch. Ges. Pathol 78, 8-14 (1994).
19. Garrod, D. R.: Desmosomes and hemidesmosomes. Curr. Opin. Cell Biol. 5, 30-40 (1993).
20. Goodwin, L., H. E. Hill, K. Raynor, L. Raszi, M. Manabe, P. Cowin: Desmoglein shows extensive homology to the cadherin family of adhesion molecules. Biochem. Biophys. Res. Commun. 173, 1224-1230 (1990).
21. Hashimoto, K., T. Hashimoto, M. Higashiyama, T. Nishikawa, D. R. Garrod, K. Yoshikawa: Detection of anti-desmocollins I and II autoantibodies in two cases of Hallopeau type pemphigus vegetans by immunoblot analysis. J. Dermatol. Sci. 7, 100-106 (1994).
22. Heid, H. W., I. Moll, W. W. Franke: Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. II. Concomitant and mutually exclusive synthesis of trichocytic and epithelial cytokeratins in diverse human and bovine tissues (hair follicle, nail bed and matrix, lingual papilla, thymic reticulum). Differentiation 37, 215-230 (1988).
23. Heid, H. W., A. Schmidt, R. Zimbelmann, S. Schäfer, S. Winter-Simanowski, S. Stumpp, M. Keith, U. Figge, M. Schnölzer, W. W. Franke: Cell type-specific desmosomal plaque proteins of the plakoglobin family: plakophilin 1 (band 6 protein). Differentiation 58, 113-131 (1994).
24. Hieda, Y., Y. Nishizawa, J. Uematsu, K. Owaribe: Identification of a new hemidesmosomal protein, HD1: a major, high molecular mass component of isolated hemidesmosomes. J. Cell Biol. 116, 1497-1506 (1992).
25. Huszar, M., O. Gigi-Leitner, R. Moll, W. W. Franke, B. Geiger: Monoclonal antibodies to various acidic (type I) cytokeratins of stratified epithelia. Selective markers for stratification on squamous cell carcinomas. Differentiation 31, 141-153 (1986).
26. Kawamura, K., K. Watanabe, T. Suzuki, T. Yamakawa, T. Kamiyama, H. Nakagawa, S. Tsurufuji: cDNA cloning and expression of a novel human desmocollin. J. Biol. Chem. 269, 26295-26302 (1994).
27. King, I. A., J. Arnemann, N. K. Spurr, R. S. Buxton: Cloning of the cDNA (Dsc1) coding for human type 1 desmocollin and its assignment to chromosome 18. Genomics 18, 185-194 (1993).
28. King, I. A., K. H. Sullivan, R. Bennett Jr., R. S. Buxton: The desmocollins of human foreskin epidermis: identification and chromosomal assignment of a third gene and expression patterns of the three isoforms. J. Invest. Dermatol. 105, 314-321 (1995).
29. Koch, P. J., M. J. Walsh, M. Schmelz, M. D. Goldschmidt, R. Zimbelmann, W. W. Franke: Identification of desmoglein, a constitutive desmosomal glycoprotein, as a member of the cadherin family of cell adhesion molecules. Eur. J. Cell Biol. 53, 1-12 (1990).
30. Koch, P. J., M. D. Goldschmidt, M. J. Walsh, R. Zimbelmann, W. W. Franke: Complete amino acid sequence of the epidermal desmoglein precursor polypeptide and identification of a second type of desmoglein gene. Eur. J. Cell Biol. 55, 200-208 (1991).
31. Koch, P. J., M. D. Golschmidt, M. J. Walsh, R. Zimbelmann, M. Schmelz, W. W. Franke: Amino acid sequence of bovine muzzle epithelial desmocollin derived from cloned cDNA: A novel subtype of desmosomal cadherins. Differentiation 47, 29-36 (1991).
32. Koch, P. J., M. D. Goldschmidt, R. Zimbelmann, R. Troyanosvsky, W. W. Franke: Complexity and expression patterns of the desmosomal cadherins. Proc. Natl. Acad. Sci. USA 89, 353-357 (1992).
33. Koch, P. J., W. W. Franke: Desmosomal cadherins: Another growing multigene family of adhesion molecules. Curr. Opin. Cell Biol. 6, 682-687 (1994).
34. Laster, A. J., T. Itoh, T. J. Palker, B. F. Haynes: The human thymic microenvironment: Thymic epithelium contains specific keratins associated with early and late stages of epidermal keratinocyte maturation. Differentiation 31, 67-77 (1986).
35. Legan, P. K., K. K. Yue, M. A. Chidgey, J. L. Holton, R. W. Wilkinson, D. R. Garrod: The bovine desmocollin family: a new gene and expression patterns reflecting epithelial cell proliferation and differentiation. J. Cell Biol. 126, 507-518 (1994).
36. Lorimer, J. E., L. S. Hall, J. P. Clarke, J. E. Collins, T. P. Fleming, D. R. Garrod: Cloning, sequence analysis and expression pattern of mouse desmocollin 2 (DSC2), a cadherin-like adhesion molecule. Mol. Membr. Biol. 11, 229-236 (1994).
37. Mechanic, S., K. Raynor, J. E. Hill, P. Cowin: Desmocollins form a distinct subset of the cadherin family of cell adhesion molecules. Proc. Natl. Acad. Sci. USA 88, 4476-4480 (1991).
38. Moll, R.: Cytokeratine als Differenzierungsmarker: Expressionsprofile von Epithelien und epithelialen Tumoren. pp. 1-197. Gustav Fischer Verlag, Stuttgart 1993.
39. Moll, R., W. W. Franke, D. Schiller, B. Geiger, R. Krepler: The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells. Cell 31, 11-24 (1982).
40. Moll, R., R. Krepler, W. W. Franke: Complex cytokeratin polypeptide patterns observed in certain human carcinomas. Differentiation 23, 256-269 (1983).
41. Moll, R., P. Cowin, H.-P. Kapprell, W. W. Franke: Biology of disease. Desmosomal proteins: new markers for identification and classification of tumors. Lab. Invest. 54, 4-25 (1986).
42. Nilles, L. A., D. A. D. Parry, E. E. Powers, B. D. Angst, R. W. Wagner, K. J. Green: Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome. J. Cell Sci. 99, 809-821 (1991).
43. Nuber, U. A., S. Schäfer, A. Schmidt, P. J. Koch, W. W. Franke: The widespread human desmocollin Dsc2 and tissue-specific patterns of synthesis of various desmocollin subtypes. Eur. J. Cell Biol. 66, 69-74 (1995).
44. Owaribe, K., Y. Nishizawa, W. W. Franke: Isolation and characterization of hemidesmosomes from bovine corneal epithelial cells. Exp. Cell Res. 192, 622-630 (1991).
45. Parrish, E. A., P. V. Steart, D. R. Garrod, R. O. Weller: Antidesmosomal monoclonal antibody in the diagnosis of intracranial tumours. J. Pathol. 153, 265-273 (1987).
46. Rheinwald, J. G., H. Green: Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell 6, 331-344 (1975).
47. Schäfer, S., S. M. Troyanovsky, H. W. Heid, L. G. Eshkind, P. J. Koch, W. W. Franke: Cytoskeletal architecture and epithelial differentiation: Molecular determinants of cell interaction and cytoskeletal filament anchorage. C. R. Acad. Sci. Paris Ser. III, 316, 1316-1323 (1993).
48. Schäfer, S., P. J. Koch, W. W. Franke: Identification of the ubiquitous human desmoglein. Dsg2, and the expression catalogue of the desmoglein subfamily of desmosomal cadherins. Exp. Cell Res. 211, 391-399 (1994).
49. Schmelz, M., R. Duden, P. Cowin, W. W. Franke: A constitutive transmembrane glycoprotein of Mr 165000 (desmoglein) in epidermal and non-epidermal desmosomes: II. Irnmunolocalization and microinjection studies. Eur. J. Cell Biol. 42, 184-199 (1986).
50. Schmidt, A., H. W. Heid, S. Schäfer, U. A. Nuber, R. Zimbelmann, W. W. Franke: Desmosomes and cytoskeletal architecture in epithelial differentiation. Cell type-specific plaque components and intermediate filament anchorage. Eur. J. Cell. Biol. 65, 229-245 (1994).
51. Schwarz, M. A., K. Owaribe, J. Kartenbeck, W. W. Franke: Desmosomes and hemidesmosomes: constitutive molecular components. Annu. Rev. Cell Biol. 6, 461-491 (1990).
52. Sun, T.-T., P. Bonitz, W. H. Burns: Cell culture of mammalian thymic epithelial cells: growth, structural and antigenic properties. Cell. Immunol. 83, 1-13 (1984).
53. Theis, D. G., P. J. Koch, W. W. Franke: Differential synthesis of type 1 and type 2 desmocollin mRNAs in human stratified epithelia. Int. J. Dev. Biol. 37, 101-110 (1993).
54. Troyanovsky, S. M., L. G. Eshkind, R. B. Troyanovsky, R. E. Leube, W. W. Franke: Contributions of cytoplasmic domains of desmosomal cadherins to desmosome assembly and intermediate filament anchorage. Cell 72, 561-574 (1993).
55. Uematsu, J., Y. Nishizawa, A. Sonnenberg, K.Owaribe: Demonstration of type II hemidesmosomes in mammary gland epithelial cell line, BMGE-H. J. Biochem. 115, 469-476 (1994).
56. Vilela, M. J., E. P. Parrish, D. H. Wright, D. R. Garrod: Monoclonal antibody to desmosomal glycoprotein 1 - a new epithelial marker for diagnostic pathology. J. Pathol. 153, 365-375 (1987).
57. Wheeler, G. N., A. E. Parker, C. L. Thomas, P. Ataliotis, D. Poynter, J. Arnemann, A. J. Rutman, S. C. Pidsley, F. M. Watt, D. A. Rees, R. S. Buxton, A. I. Mageee: Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules. Proc. Natl. Acad. Sci. USA 88, 4796-4800 (1991).
58. Yue, K. K., J. L. Holton, J. P. Clarke, J. L. Hyam, T. Hashimoto, M. A. Chidgey, D. R. Garrod: Characterisation of a desmocollin isoform (bovine DSC3) exclusively expressed in lower layers of stratified epithelia. J. Cell Sci. 108, 2163-2173 (1995).