Role of syndecan-3 polymorphisms in obesity and female hyperandrogenism

Journal of Molecular Medicine

Volumn 87, Issue 12, 2009, Pages 1241-1250

  Schüring, Andreas N ^a   Lutz, Friederike ^a   Tüttelmann, Frank ^a   Gromoll, Jörg ^a   Kiesel, Ludwig ^a   Götte, Martin ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Endocrinology; Fertility; Glycobiology; Gynecology; Obesity; Polymorphism

Indexed keywords

ANDROSTENEDIONE; FOLLITROPIN; HYDROXYPROGESTERONE; LUTEINIZING HORMONE; SEX HORMONE BINDING GLOBULIN; SYNDECAN 3;

ADULT; ARTICLE; ASIAN; BODY MASS; CAUCASIAN; CONTROLLED STUDY; ETHNIC DIFFERENCE; FEMALE; FEMALE INFERTILITY; GENE FREQUENCY; HAPLOTYPE; HUMAN; HYPERANDROGENISM; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; OBESITY; POPULATION GENETICS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BODY MASS INDEX; BODY WEIGHT; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; HYPERANDROGENISM; INFERTILITY; KOREA; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; SYNDECAN-3; YOUNG ADULT;

EID: 70949106264     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-009-0529-1     Document Type: Article

References (32)

1. M Bernfield M Götte PW Park O Reizes ML Fitzgerald J Lincecum M Zako 1999 Functions of cell surface heparan sulfate proteoglycans Annu Rev Biochem 68 729 777 10.1146/annurev.biochem.68.1.729 1:CAS:528:DyaK1MXlvFajt7w%3D 10872465 (Pubitemid 29449208)
2. Y Chen M Götte J Liu PW Park 2008 Microbial subversion of heparan sulfate proteoglycans Mol Cells 26 415 426 18799929
3. O Reizes SC Benoit DJ Clegg 2008 The role of syndecans in the regulation of body weight and synaptic plasticity Int J Biochem Cell Biol 40 28 45 10.1016/j.biocel.2007.06.011 1:CAS:528:DC%2BD2sXht1ylsb3P 17698399 (Pubitemid 350052659)
4. EJ Davies FH Blackhall JH Shanks G David AT McGown R Swindell RJ Slade P Martin-Hirsch JT Gallagher GC Jayson 2004 Distribution and clinical significance of heparan sulfate proteoglycans in ovarian cancer Clin Cancer Res 10 5178 5186 10.1158/1078-0432.CCR-03-0103 1:CAS:528:DC%2BD2cXmsVerurw%3D 15297422 (Pubitemid 39099793)
5. A Hjelm Cluff A Malmström B Tingåker G David G Ekman-Ordeberg 2005 Normal labor associated with changes in uterine heparan sulfate proteoglycan expression and localization Acta Obstet Gynecol Scand 84 217 224 10.1111/j.0001-6349.2005.00484.x 15715528 (Pubitemid 40333100)
6. SE Gould WB Upholt RA Kosher 1992 Syndecan 3: a member of the syndecan family of membrane-intercalated proteoglycans that is expressed in high amounts at the onset of chicken limb cartilage differentiation Proc Natl Acad Sci U S A 89 3271 3275 10.1073/pnas.89.8.3271 1:CAS:528:DyaK3sXhvVyjtbw%3D 1565618
7. L Fuentealba DJ Carey E Brandan 1999 Antisense inhibition of syndecan-3 expression during skeletal muscle differentiation accelerates myogenesis through a basic fibroblast growth factor-dependent mechanism J Biol Chem 274 37876 37884 10.1074/jbc.274.53.37876 1:CAS:528:DC%2BD3cXkt1Gmsw%3D%3D 10608853 (Pubitemid 30026854)
8. S Zertal-Zidani A Bounacer R Scharfmann 2007 Regulation of pancreatic endocrine cell differentiation by sulphated proteoglycans Diabetologia 50 585 595 10.1007/s00125-006-0571-2 1:CAS:528:DC%2BD2sXhtlKis7c%3D 17221210 (Pubitemid 46215502)
9. O Reizes J Lincecum Z Wang O Goldberger L Huang M Kaksonen R Ahima MT Hinkes GS Barsh H Rauvala, et al. 2001 Transgenic expression of syndecan-1 uncovers a physiological control of feeding behavior by syndecan-3 Cell 106 105 116 10.1016/S0092-8674(01)00415-9 1:CAS:528:DC%2BD3MXlsVCqtrc%3D 11461706 (Pubitemid 32709962)
10. AD Strader O Reizes SC Woods SC Benoit RJ Seeley 2004 Mice lacking the syndecan-3 gene are resistant to diet-induced obesity J Clin Invest 114 1354 1360 1:CAS:528:DC%2BD2cXpsFCgt78%3D 15520868
11. E Carmina S Bucchieri A Esposito A Del Puente P Mansueto F Orio G Di Fede G Rini 2007 Abdominal fat quantity and distribution in women with polycystic ovary syndrome and extent of its relation to insulin resistance J Clin Endocrinol Metab 92 2500 2505 10.1210/jc.2006-2725 1:CAS:528: DC%2BD2sXotVyls78%3D 17405838 (Pubitemid 47037349)
12. JE Nestler DJ Jakubowicz AF de Vargas C Brik N Quintero F Medina 1998 Insulin stimulates testosterone biosynthesis by human thecal cells from women with polycystic ovary syndrome by activating its own receptor and using inositolglycan mediators as the signal transduction system J Clin Endocrinol Metab 83 2001 2005 10.1210/jc.83.6.2001 1:CAS:528:DyaK1cXjslCgurs%3D 9626131 (Pubitemid 28496328)
13. JE Nestler LP Powers DW Matt KA Steingold SR Plymate RS Rittmaster JN Clore WG Blackard 1991 A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome J Clin Endocrinol Metab 72 83 89 10.1210/jcem-72-1-83 1:STN:280:DyaK3M%2FptleqsA%3D%3D 1898744
14. HF Escobar-Morreale JL San Millán 2007 Abdominal adiposity and the polycystic ovary syndrome Trends Endocrinol Metab 18 266 272 10.1016/j.tem.2007.07.003 1:CAS:528:DC%2BD2sXpvFGksro%3D 17693095 (Pubitemid 47332217)
15. RS Legro D Driscoll JF Strauss 3rd J Fox A Dunaif 1998 Evidence for a genetic basis for hyperandrogenemia in polycystic ovary syndrome Proc Natl Acad Sci U S A 95 14956 14960 10.1073/pnas.95.25.14956 1:CAS:528:DyaK1cXotVGlsr0%3D 9843997 (Pubitemid 29003738)
16. M Kashar-Miller R Azziz 1999 Heritability and the risk of developing androgen excess J Steroid Biochem Mol Biol 69 261 268 10.1016/S0960-0760(99) 00043-6 1:CAS:528:DyaK1MXktlOmtbo%3D 10419000 (Pubitemid 29305544)
17. K Akita S Fushiki T Fujimoto S Munesue M Inoue K Oguri M Okayama I Yamashina H Nakada 2001 Identification of the core protein carrying the Tn antigen in mouse brain: specific expression on syndecan-3 Cell Struct Funct 26 271 278 10.1247/csf.26.271 1:CAS:528:DC%2BD38XhtFSju74%3D 11831359 (Pubitemid 34110813)
18. E Ha MJ Kim BK Choi JJ Rho DJ Oh TH Rho KH Kim HJ Lee DH Shin SV Yim, et al. 2006 Positive association of obesity with single nucleotide polymorphisms of syndecan 3 in the Korean population J Clin Endocrinol Metab 91 5095 5099 10.1210/jc.2005-2086 1:CAS:528:DC%2BD28XhtlGru7jM 17018662 (Pubitemid 44917356)
19. MM Zain RJ Norman 2008 Impact of obesity on female fertility and fertility treatment Womens Health 4 183 194
20. World Health Organization (1998) Obesity: preventing and managing the global epidemic. Report on a WHO consultation on obesity; June 3-5, 1997; Geneva, Switzerland. WHO/NUT/NCD/98.1; Geneva
21. JC Barrett B Fry J Maller MJ Daly 2005 Haploview: analysis and visualization of LD and haplotype maps Bioinformatics 21 263 265 10.1093/bioinformatics/bth457 1:CAS:528:DC%2BD2MXkt1WitQ%3D%3D 15297300 (Pubitemid 40202029)
22. S Musatov W Chen DW Pfaff CV Mobbs XJ Yang DJ Clegg MG Kaplitt S Ogawa 2007 Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome Proc Natl Acad Sci U S A 104 2501 2506 10.1073/pnas.0610787104 1:CAS:528:DC%2BD2sXisVSgt7g%3D 17284595 (Pubitemid 46391425)
23. Q Gao G Mezei Y Nie Y Rao CS Choi I Bechmann C Leranth D Toran-Allerand CA Priest JL Roberts, et al. 2007 Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals Nat Med 13 89 94 10.1038/nm1525 1:CAS:528:DC%2BD2sXhvFWisQ%3D%3D 17195839 (Pubitemid 46067391)
24. HG Burger 2002 Androgen production in women Fertil Steril 77 Suppl 4 S3 S5 10.1016/S0015-0282(02)02985-0 12007895
25. J Hirshfeld-Cytron RB Barnes DA Ehrmann A Caruso MM Mortensen RL Rosenfield 2009 Characterization of functionally typical and atypical types of polycystic ovary syndrome J Clin Endocrinol Metab 94 1587 1594 10.1210/jc.2008-2248 1:CAS:528:DC%2BD1MXlvVCqtrc%3D 19240152
26. AJ Morales GA Laughlin T Bützow H Maheshwari G Baumann SS Yen 1996 Insulin, somatotropic, and luteinizing hormone axes in lean and obese women with polycystic ovary syndrome: common and distinct features J Clin Endocrinol Metab 81 2854 2864 10.1210/jc.81.8.2854 1:CAS:528:DyaK28XkvFWrsL4%3D 8768842 (Pubitemid 26326301)
27. M Pugeat JC Crave J Tourniaire MG Forest 1996 Clinical utility of sex hormone-binding globulin measurement Horm Res 45 148 155 10.1159/000184778 1:CAS:528:DyaK28XhvFKnurs%3D 8964574
28. AD Coviello RS Legro A Dunaif 2006 Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance J Clin Endocrinol Metab 91 492 497 10.1210/jc.2005-1666 1:CAS:528:DC%2BD28XhsFKntbw%3D 16249280 (Pubitemid 43236914)
29. Rongioletti F, Donati P, Amantea A, Ferrara G, Montinari M, Santoro F, Parodi A (2009) Obesity-associated lymphoedematous mucinosis. J Cutan Pathol 2009 Feb 10. (Epub ahead of print) PMID: 19222694
30. CB Mendes-de-Aguiar B Costa-Silva M Alvarez-Silva CI Tasca AG Trentin 2008 Thyroid hormone mediates syndecan expression in rat neonatal cerebellum Cell Mol Neurobiol 28 795 801 10.1007/s10571-008-9260-7 1:CAS:528: DC%2BD1cXhtFKmu77I 18219570
31. CV Zerbinatti CA Dyer 1999 Apolipoprotein E peptide stimulation of rat ovarian theca cell androgen synthesis is mediated by members of the low density lipoprotein receptor superfamily Biol Reprod 61 665 672 10.1095/biolreprod61.3. 665 1:CAS:528:DyaK1MXlsFCqsbw%3D 10456843 (Pubitemid 29402626)
32. LC Wilsie AM Gonzales RA Orlando 2006 Syndecan-1 mediates internalization of apoE-VLDL through a low density lipoprotein receptor-related protein (LRP)-independent, non-clathrin-mediated pathway Lipids Health Dis 5 23 10.1186/1476-511X-5-23 16945147 (Pubitemid 44543604)