Positive association of obesity with single nucleotide polymorphisms of syndecan 3 in the Korean population

Journal of Clinical Endocrinology and Metabolism

Volumn 91, Issue 12, 2006, Pages 5095-5099

  Ha, Eunyoung ^a   Kim, Mi Ja ^b   Choi, Bong Keun ^a   Rho, Jung Jae ^c   Oh, Dong Jae ^c   Rho, Tae Hoon ^c   Kim, Kyu Hyun ^c   Hee, Jae Lee ^d   Shin, Dong Hoon ^e   Sung, Vin Yim ^a   Hyung, Hwan Baik ^a   Chung, Joo Ho ^a   Jong, Woo Kim ^a,f  

^a Kyung Hee University Hospital   (South Korea)

^b Dongduk Women's University   (South Korea)

^c Imagine Obesity Research Institute   (South Korea)

^d Kangwon National University   (South Korea)

^e Keimyung University   (South Korea)

^f Kyung Hee University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; SYNDECAN 3;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY MASS; BRAIN REGION; CONTROLLED STUDY; ETHNICITY; FEMALE; GENE FREQUENCY; GENOTYPE; HUMAN; KOREA; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 33845485497     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2005-2086     Document Type: Article

References (20)

1. Zimmet P, Alberti KG, Shaw J 2001 Global and societal implications of the diabetes epidemic. Nature 414:782-787
2. Carr DB, Utzschneider KM, Hull RL, Kodama K, Retzlaff BM, Brunzell JD, Shofer JB, Fish BE, Knopp RH, Kahn SE 2004 Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome. Diabetes 53:2087-2094
3. Boden G 1997 Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 46:3-10
4. Seppälä-Lindroos A, Vehkavaara S, Häkkinen AM, Goto T, Westerbacka J, Sovijärvi A, Halavaara J, Yki-Järvinen H 2002 Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. J Clin Endocrinol Metab 87:3023-3028
5. Bajaj M, Suraamornkul S, Pratipanawatr T, Hardies LJ, Pratipanawatr W, Glass L, Cersosimo E, Miyazaki Y, DeFronzo RA 2003 Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in patients with type 2 diabetes. Diabetes 52:1364-1370
6. Friedman JM, Halaas JL 1998 Leptin and the regulation of body weight in mammals. Nature 395:763-770
7. Elmquist JK, Elias CF, Saper CB 1999 From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 22:221-232
8. Kalra SP, Dube MG, Pu S, Xu B, Horvath TL, Kalra PS 1999 Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20:68-100
9. Schwartz MW, Woods SC, Porte Jr D, Seeley RJ, Baskin DG 2000 Central nervous system control of food intake. Nature 404:661-671
10. Spiegelman BM, Flier JS 2001 Obesity and the regulation of energy balance. Cell 104:531-534
11. Wynne K, Stanley S, McGowan B, Bloom S 2005 Appetite control. J Endocrinol 184:291-318
12. Reizes O, Lincecum J, Wang Z, Goldberger O, Huang L, Kaksonen M, Ahima R, Hinkes MT, Barsh GS, Rauvala H, Bernfield M 2001 Transgenic expression of syndecan-1 uncovers a physiological control of feeding behavior by syndecan-3. Cell 106:105-116
13. Strader AD, Reizes O, Woods SC, Benoit SC, Seeley RJ 2004 Mice lacking the syndecan-3 gene are resistant to diet-induced obesity. J Clin Invest 114:1354-1360
14. Bernfield M, Götte M, Park PW, Reizes O, Fitzgerald ML, Lincecum J, Zako M 1999 Functions of cell surface heparin sulfate proteoglycans. Annu Rev Biochem 68:729-777
15. Rapraeger AC, Ott VL 1998 Molecular interactions of the syndecan core proteins. Curr Opin Cell Biol 10:620-628
16. Woods A, Couchman JR 1998 Syndecan synergistic activators of cell adhesion. Trends Cell Biol 8:189-192
17. Terwilliger JD, Ott J 1994 Linkage disequilibrium between alleles at marker loci. In: Handbook of human genetic linkage. 1st ed. Baltimore: Johns Hopkins University; 188-198
18. Reizes O, Benoit SC, Strader AD, Clegg DJ, Akunuru S, Seeley RJ 2003 Syndecan-3 modulates food intake by interaction with the melanocortin/AgRP pathway. Ann NY Acad Sci 994:66-73
19. Berndt C, Casaroli-Marano RP, Vilaró S, Reina M 2001 Cloning and characterization of human syndecan-3. J Cell Biol 82:246-259
20. Carey DJ 1997 Syndecans: multifunctional cell-surface coreceptors. Biochem J 327:1-16