Menthol induces cell death via the TRPM8 channel in the human bladder cancer cell line T24

Oncology

Volumn 77, Issue 6, 2010, Pages 335-341

  Li, Qin ^a   Wang, Xinghuan ^b   Yang, Zhonghua ^b   Wang, Bin ^a   Li, Shilin ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

Bladder cancer; Cell death; Menthol; T24 cell line; TRPM8

Indexed keywords

CALCIUM; MENTHOL; SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRANSIENT RECEPTOR POTENTIAL MELASTATIN 8; UNCLASSIFIED DRUG; TRPM8 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BLADDER CANCER; CALCIUM CELL LEVEL; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL DEATH; CELL MEMBRANE; CELL MEMBRANE DEPOLARIZATION; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MITOCHONDRIAL MEMBRANE POTENTIAL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; BLADDER TUMOR; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECT; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

APOPTOSIS; CALCIUM; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MENTHOL; TRPM CATION CHANNELS; URINARY BLADDER NEOPLASMS;

EID: 70849085425     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000264627     Document Type: Article

References (41)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ: Cancer statistics, 2008. CA Cancer J Clin 2008; 58: 71-96. (Pubitemid 351521864)
2. Han RF, Pan JG: Can intravesical bacillus Calmette-Guérin reduce recurrence in patients with superficial bladder cancer? A meta-analysis of randomized trials. Urology 2006; 67: 1216-1223.
3. Hinotsu S, Akaza H, Isaka S, Kanetake H, Kubota Y, Kuroda M, Shinohara N, Shinka T, Tachibana M, Naito S, Hirao Y: Sustained prophylactic effect of intravesical bacille Calmette-Guérin for superficial bladder cancer: a smoothed hazard analysis in a randomized prospective study. Urology 2006; 67: 545-549. (Pubitemid 43343539)
4. Pawinski A, Sylvester R, Kurth KH, Bouffioux C, van der Meijden A, Parmar MK, Bijnens L: A combined analysis of European Organization for Research and Treatment of Cancer, and Medical Research Council randomized clinical trials for the prophylactic treatment of stage TaT1 bladder cancer. European Organization for Research and Treat- ment of Cancer Genitourinary Tract Cancer Cooperative Group and the Medical Research Council Working Party on Superficial Bladder Cancer. J Urol 1996; 156: 1934- 1940, discussion 1940-1941. (Pubitemid 26378022)
5. Patel T, Ishiuji Y, Yosipovitch G: Menthol: a refreshing look at this ancient compound. J Am Acad Dermatol 2007; 57: 873-878. (Pubitemid 47553064)
6. Werley MS, Coggins CR, Lee PN: Possible effects on smokers of cigarette mentholation: a review of the evidence relating to key research questions. Regul Toxicol Pharmacol 2007; 47: 189-203.
7. Mergler S, Strowski MZ, Kaiser S, Plath T, Giesecke Y, Neumann M, Hosokawa H, Kobayashi S, Langrehr J, Neuhaus P, Plockinger U, Wiedenmann B, Grotzinger C: Transient receptor potential channel TRPM8 agonists stimulate calcium influx and neurotensin secretion in neuroendocrine tumor cells. Neuroendocrinology 2007; 85: 81-92. (Pubitemid 46725694)
8. Yamamura H, Ugawa S, Ueda T, Morita A, Shimada S: TRPM8 activation suppresses cellular viability in human melanoma. Am J Physiol Cell Physiol 2008; 295:C296-C301. (Pubitemid 352755761)
9. Lu HF, Hsueh SC, Yu FS, Yang JS, Tang NY, Chen SC, Chung JG: The role of Ca 2+ in (-)- menthol-induced human promyelocytic leukemia HL-60 cell death. In Vivo 2006; 20: 69-75.
10. Bernhardt G, Biersack B, Bollwein S, Schobert R, Zoldakova M: Terpene conjugates of diaminedichloridoplatinum(II) complexes: antiproliferative effects in HL-60 leukemia, 518A2 melanoma, and HT-29 colon cancer cells. Chem Biodivers 2008; 5: 1645-1659.
11. MacDougall JM, Fandrick K, Zhang X, Serafin SV, Cashman JR: Inhibition of human liver microsomal (S)-nicotine oxidation by (-)-menthol and analogues. Chem Res Toxicol 2003; 16: 988-993. (Pubitemid 37047916)
12. Wondergem R, Ecay TW, Mahieu F, Owsianik G, Nilius B: HGF/SF and menthol increase human glioblastoma cell calcium and migration. Biochem Biophys Res Commun 2008; 372: 210-215.
13. Lin JP, Lu HF, Lee JH, Lin JG, Hsia TC, Wu LT, Chung JG: (-)-Menthol inhibits DNA topoisomerases I, II alpha and beta and promotes NF-kappaB expression in human gastric cancer SNU-5 cells. Anticancer Res 2005; 25: 2069-2074.
14. Beck B, Bidaux G, Bavencoffe A, Lemonnier L, Thebault S, Shuba Y, Barrit G, Skryma R, Prevarskaya N: Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators. Cell Calcium 2007; 41: 285-294. (Pubitemid 46201504)
15. Kim SH, Nam JH, Park EJ, Kim BJ, Kim SJ, So I, Jeon JH: Menthol regulates TRPM8-independent processes in PC-3 prostate cancer cells. Biochim Biophys Acta 2009; 1792: 33-38.
16. Park EJ, Kim SH, Kim BJ, Kim SY, So I, Jeon JH: Menthol enhances an antiproliferative activity of 1alpha,25-dihydroxyvitamin D(3) in LNCaP cells. J Clin Biochem Nutr 2009; 44: 125-130.
17. Thebault S, Lemonnier L, Bidaux G, Flourakis M, Bavencoffe A, Gordienko D, Roudbaraki M, Delcourt P, Panchin Y, Shuba Y, Skryma R, Prevarskaya N: Novel role of cold/ menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells. J Biol Chem 2005; 280: 39423-39435. (Pubitemid 41713900)
18. Zhang L, Barritt GJ: Evidence that TRPM8 is an androgen-dependent Ca 2+ channel required for the survival of prostate cancer cells. Cancer Res 2004; 64: 8365-8373. (Pubitemid 39491776)
19. Tsavaler L, Shapero MH, Morkowski S, Laus R: Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins. Cancer Res 2001; 61: 3760-3769. (Pubitemid 32694990)
20. Patapoutian A, Peier AM, Story GM, Viswanath V: ThermoTRP channels and beyond: mechanisms of temperature sensation. Nat Rev Neurosci 2003; 4: 529-539. (Pubitemid 37271364)
21. Turner H, Fleig A, Stokes A, Kinet JP, Penner R: Discrimination of intracellular calcium store subcompartments using TRPV1 (transient receptor potential channel, vanilloid subfamily member 1) release channel activity. Biochem J 2003; 371: 341-350. (Pubitemid 36547616)
22. Legrand G, Humez S, Slomianny C, Dewailly E, Vanden Abeele F, Mariot P, Wuytack F, Prevarskaya N: Ca 2+ pools and cell growth. Evidence for sarcoendoplasmic Ca 2+ -ATPases 2B involvement in human prostate cancer cell growth control. J Biol Chem 2001; 276: 47608-47614. (Pubitemid 37373147)
23. Thebault S, Flourakis M, Vanoverberghe K, Vandermoere F, Roudbaraki M, Lehen'kyi V, Slomianny C, Beck B, Mariot P, Bonnal JL, Mauroy B, Shuba Y, Capiod T, Skryma R, Prevarskaya N: Differential role of transient receptor potential channels in Ca 2+ entry and proliferation of prostate cancer epithelial cells. Cancer Res 2006; 66: 2038-2047. (Pubitemid 43294912)
24. Vanoverberghe K, Vanden Abeele F, Mariot P, Lepage G, Roudbaraki M, Bonnal JL, Mauroy B, Shuba Y, Skryma R, Prevarskaya N: Ca 2+ homeostasis and apoptotic resistance of neuroendocrine-differentiated prostate cancer cells. Cell Death Differ 2004; 11: 321-330. (Pubitemid 38313141)
25. Vanden Abeele F, Roudbaraki M, Shuba Y, Skryma R, Prevarskaya N: Store-operated Ca 2+ current in prostate cancer epithelial cells. Role of endogenous Ca 2+ transporter type 1. J Biol Chem 2003; 278: 15381-15389. (Pubitemid 36799877)
26. Sherkheli MA, Gisselmann G, Vogt Eisele AK, Doerner JF, Hatt H: Menthol derivative WS-12 selectively activates transient receptor potential melastatin-8 (TRPM8) ion channels. Pak J Pharm Sci 2008; 21: 370-378.
27. Yang ZH, Wang XH, Wang HP, Hu LQ: Effects of TRPM8 on the proliferation and motility of prostate cancer PC-3 cells. Asian J Androl 2009; 11: 157-165.
28. Lin JP, Li YC, Lin WC, Hsieh CL, Chung JG: Effects of (-)-menthol on arylamine N-ace tyltransferase activity in human liver tumor cells. Am J Chin Med 2001; 29: 321-329.
29. Du S, Araki I, Kobayashi H, Zakoji H, Sawada N, Takeda M: Differential expression profile of cold (TRPA1) and cool (TRPM8) receptors in human urogenital organs. Urology 2008; 72: 450-455.
30. Stein RJ, Santos S, Nagatomi J, Hayashi Y, Minnery BS, Xavier M, Patel AS, Nelson JB, Futrell WJ, Yoshimura N, Chancellor MB, De Miguel F: Cool (TRPM8) and hot (TRPV1) receptors in the bladder and male genital tract. J Urol 2004; 172: 1175-1178. (Pubitemid 39096495)
31. McKemy DD, Neuhausser WM, Julius D: Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 2002; 416: 52-58. (Pubitemid 34215395)
32. Mustafa S, Oriowo M: Cooling-induced contraction of the rat gastric fundus: mediation via transient receptor potential (TRP) cation channel TRPM8 receptor and Rho-kinase activation. Clin Exp Pharmacol Physiol 2005; 32: 832-838. (Pubitemid 43906526)
33. Yang XR, Lin MJ, McIntosh LS, Sham JS: Functional expression of transient receptor potential melastatin- and vanilloid-related channels in pulmonary arterial and aortic smooth muscle. Am J Physiol Lung Cell Mol Physiol 2006; 290:L1267-L1276.
34. Tsuzuki K, Xing H, Ling J, Gu JG: Mentholinduced Ca 2+ release from presynaptic Ca 2+ stores potentiates sensory synaptic transmission. J Neurosci 2004; 24: 762-771. (Pubitemid 38166502)
35. Olah Z, Szabo T, Karai L, Hough C, Fields RD, Caudle RM, Blumberg PM, Iadarola MJ: Ligand-induced dynamic membrane changes and cell deletion conferred by vanilloid receptor 1. J Biol Chem 2001; 276: 11021-11030. (Pubitemid 38089283)
36. Turrens JF: Superoxide production by the mitochondrial respiratory chain. Biosci Rep 1997; 17: 3-8. (Pubitemid 27032873)
37. Chance B, Sies H, Boveris A: Hydroperoxide metabolism in mammalian organs. Physiol Rev 1979; 59: 527-605. (Pubitemid 9236599)
38. Cai J, Yang J, Jones DP: Mitochondrial control of apoptosis: the role of cytochrome c. Biochim Biophys Acta 1998; 1366: 139-149. (Pubitemid 28467028)
39. Costantini P, Jacotot E, Decaudin D, Kroemer G: Mitochondrion as a novel target of anticancer chemotherapy. J Natl Cancer Inst 2000; 92: 1042-1053. (Pubitemid 30616479)
40. Sanchez AM, Sanchez MG, Malagarie- Cazenave S, Olea N, Diaz-Laviada I: Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin. Apoptosis 2006; 11: 89-99. (Pubitemid 43151647)
41. Chow J, Norng M, Zhang J, Chai J: TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells - mechanisms behind a possible new 'hot' cancer treatment. Biochim Biophys Acta 2007; 1773: 565-576. (Pubitemid 46441507)