Novel and potent inhibitors of fatty acid synthase derived from catechins and their inhibition on MCF-7 cells

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 24, Issue 3, 2009, Pages 623-631

  Zhang, Shu Yan ^a   Ma, Xiao Feng ^a   Zheng, Chao Gu ^b   Wang, Yan ^a   Cao, Xue Li ^c   Tian, Wei Xi ^a  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^b INSTITUTE OF BIOPHYSICS   (China)

^c BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY   (China)

Author keywords

Anticancer activity; Catechins; Fatty acid synthase; Inhibitor; Oligomers

Indexed keywords

ACID; ACRYLIC ACID; CATECHIN; EPIGALLOCATECHIN GALLATE; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE INHIBITOR; OLIGOMER; ENZYME INHIBITOR; HYDROCHLORIC ACID; PROPIONIC ACID DERIVATIVE; SULFURIC ACID;

ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; DRUG INHIBITION; ENZYME STABILITY; HEATING; HUMAN; HUMAN CELL; PH; PRIORITY JOURNAL; ROOM TEMPERATURE; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; BREAST NEOPLASMS; CHEMISTRY; FEMALE; IC50; KINETICS; MASS SPECTROMETRY; PATHOLOGY; SYNTHESIS; TUMOR CELL LINE;

BREAST NEOPLASMS; CATECHIN; CELL LINE, TUMOR; ENZYME INHIBITORS; FATTY ACID SYNTHASES; FEMALE; HUMANS; HYDROCHLORIC ACID; INHIBITORY CONCENTRATION 50; KINETICS; PROPIONATES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SULFURIC ACIDS;

EID: 70749145955     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360802319678     Document Type: Article

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