The influence of various amphiphilic excipients on the physicochemical properties of carbamazepine-loaded microparticles

Journal of Microencapsulation

Volumn 26, Issue 3, 2009, Pages 251-262

  Barakat, Nahla S ^a   Elanazi, Fars K ^a   Almurshedi, Alanood S ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Amphiphilic excipients; Carbamazepine; Dissolution rate studies; Emulsion congealing technique; Hydrogenated castor oil

Indexed keywords

AMPHOPHILE; CARBAMAZEPINE; DOCUSATE SODIUM; EXCIPIENT; GELUCIRE; HYDROGENATED CASTOR OIL; LABRASOL; POLOXAMER; TOCOFERSOLAN; WAX;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DIFFUSION; DISSOLUTION; EMULSION; INFRARED SPECTROSCOPY; LOW TEMPERATURE; PARTICLE SIZE; PHYSICAL CHEMISTRY; POLYMERIZATION;

ANTICONVULSANTS; CALORIMETRY, DIFFERENTIAL SCANNING; CARBAMAZEPINE; CASTOR OIL; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; EXCIPIENTS; HYDROGENATION; MICROSPHERES; PARTICLE SIZE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE-ACTIVE AGENTS;

EID: 70749100256     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.1080/02652040802305113     Document Type: Article

References (34)

1. Reithmeier H, Herrmann J, Gopferich A. Development and characterization of lipid microparticles as a drug carrier for somatostatin. Int J Pharm. 2001;218:133-143
2. Gasco MR. 1993. Method for producing solid lipid microspheres having a narrow size distribution. US pat. 5250236.
3. Mehnert W, Mädder K. Solid lipid nanoparticles production, characterization and application. Adv Drug Deliv Rev. 2001; 47:165-196
4. Mü ller RH, Radtke M, Wissing SA. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparation. Adv Drug Deliv Rev. 2002; 54(Suppl 1):S131-55.
5. Paradkar AR, Maheshwari M, Ketkar AR, Chauhan B. Preparation and evaluation of ibuprofen beads by melt solidification technique. Int J Pharm. 2003;255:33-42. (Pubitemid 36369588)
6. Barakat NS, Yassin AB. In Vitro characterization of carbamazepineloaded precifac lipospheres. Drug Deliv. 2006;13:95-104.
7. Lamprecht A, Bouligand Y, Benoit JP. New lipid nanocapsules exhibit sustained release properties for amiodarone. J Contr Rel. 2002;84:59-68.
8. Hu FQ, Hong Y, Yuan H. Preparation and characterization of solid lipid nanoparticles containing peptide. Int J Pharm. 2004; 273:29-35. (Pubitemid 38317037)
9. Venkateswarlu V, Manjunath K. Preparation, characterization and in vitro release kinetics of clozapine solid lipid nanoparticles. J Contr Rel. 2004;95:627-638
10. Bourgeois BFD, Wad N. Individual and combined epileptic and neurotoxic activity of Carbamazepine and carbamazepine-10, 11-epoxide in mice. J Pharmacol Exp Ther. 1984;231:411-415
11. Perrucca E, Richens A. Clinical pharmacokinetics of antiepileptic drugs. In: Janz D, Frey HH, editors. Antiepileptic drugs. Handbook of experimental pharmacology. Berlin: Springer-Verlag; 1984. Chapter 9.
12. Cramer JA, Mattson RH, Prevey MC, Scheyer RD, Ovellette VL. How often is medication taken as prescribed? A novel assessment technique. J Am Med Ass. 1989;261:3273-3277
13. Fonner DE Jr, Banker GS, Swarbrick J. Micrometrics of granular pharmaceutical solids I: Physical properties of particles prepared by five different granulation methods. J Pharm Sci. 1966; 55:181-186
14. Carr R. Classifying flow properties of solids. Chem Eng. 1965; 72:69-72.
15. Korsmeyer RW, Gurny R, Doelker EM, Buri P, Peppas NA. Mechanism of solute release from porous hydrophilic polymers. Int J Pharm. 1983;15:25-35.
16. Voegele D, Brockmeier D, Von Hattingberg HM, Lippold BC. Die mittlere Auflosezeit-ein parameter zur prüfung von liberationsbedingungen auf vergleichbarkeit. Acta Pharm Techno. 1983;29:167-174
17. Khan KA. The concept of dissolution efficiency. J Pharm Pharmacol. 1975;27:48-49
18. Trotta M, Debernard F, Caputo O. Preparation of solid-lipid nanoparticles by a solvent emulsification diffusion technique. Int J Pharm. 2003;257:153-160
19. Rustichelli C, Gamberin G, Ferioli V, Gamberini M, Ficarra R, Tommasini S. Solid-state study of polymorphic drugs: Carbamazepine. J Pharm Biomed Anal. 2000;23:41-54.
20. Shin SC, Oh Kim J. Physicochemical characterization of solid dispersion of furosemide with TPGS. Int J Pharm. 2003; 251:79-84.
21. Bodmeier R, Chen H. Preparation and characterization of microspheres containing the anti-inflammatory agents, Indomethacin, ibuprofen, and ketroprofen. J Contr Rel. 1989; 10:167-175
22. Jones DS, Pearce KJ. Investigation of the effects of some process variables on microencapsulation of propranolol HCl by solvent evaporation method. Int J Pharm. 1995;118:99-205.
23. Bettini R, Bonassi L, Castoro V, Rossi A, Zema L, Gazzaniga A, et al. Solubility and conversion of carbamazepine polymorphs in supercritical carbon dioxide. Eur J Pharma Sci. 2001;13:281-286
24. Naima Z, Toscani S, Gines-Dorado J-M, Chemtob C, Ceolin R, Dugue J. interactions between carbamazepine and polyethylene glycol (PEG 6000): Characterization of the physical solid dispersed and eutecticmixtures. Eur J Pharm Sci. 2001;12:395-404.
25. Moneghini M, Kikic I, Voinovich D, Perissutti B, Filipovic-Grcic J. Processing of carbamazepine-PEG 4000 solid dispersions with supercritical carbon dioxide: Preparation, characterisation, and in vitro dissolution. Int J Pharm. 2001;222:129-138
26. Won DH, Kim MS, Lee S, Park JS, Hwang SJ. Improved physicochemical characteristics of felodipine solid dispersion particles by supercritical anti-solvent precipitation process. Int J Pharm. 2005; 301:199-208.
27. Pongpaibul Y, Price JC, Whitworth CW. Preparation and evaluation of controlled release Indomethacin microspheres. Drug Dev Ind Pharm. 1984;10:1597-1616
28. Lemos-Senna E, Wouessidjewe D, Lesieur S, Duchene D. Preparation of amphiphilic cyclodextrin nanospheres using the emulsification solvent evaporation method. Influence of the surfactant on preparation and hydrophobic drug loading. Int J Pharm. 1998;170:119-128
29. Kabanov AV, Nazarova IR, Astafieva IV. Micelle formation and solubilization of fluorescent probes in poly-(oxyethylene-b-oxypropylene- b-oxyethylene) solutions. Macromolecules. 1995; 28:2303-2314
30. Alakhov V, Pietrzynski G, Patel K. Pluronic block copolymers and pluronic poly(acrylic acid) microgels in oral delivery of megestrol acetate. J Pharm Pharmacol. 2004;56:1233-1241
31. Wu SH, Hopkins WK. Characteristics of D-tocopheryl PEG 1000 succinate for applications as an absorption enhancer in drug delivery systems. Pharm Tech. 1999;23:52-60.
32. Dordunoo SK, Ford JL, Rubinstein MH. Preformulation studies on solid dispersions containing triameterene or teazepam in polyethylene glycols or Gelucire 44/14 for liquid filling of hard gelatin capsules. Drug Dev Ind Pharm. 1991;17:1685-1713
33. Mu L, Feng SS. TPGS used as emulsifier in the solvent evaporation/ extraction technique for fabrication of polymeric nanospheres for controlled release of paclitaxel. J Contr Rel. 2002;80:129-144
34. Tian F, Saville DJ, Gordon KC, Strachan CJ, Axel Zeitler J, Sandler N, et al. The influence of various excipients on the conversion kinetics of carbamazepine polymorphs in aqueous suspension. J Pharm Pharmacol. 2007;59:193-201.