Preparation of amphiphilic cyclodextrin nanospheres using the emulsification solvent evaporation method. Influence of the surfactant on preparation and hydrophobic drug loading

International Journal of Pharmaceutics

Volumn 170, Issue 1, 1998, Pages 119-128

  Lemos Senna, E ^a   Wouessidjewe, D ^b   Lesieur, S ^a   Duchene D ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b UNIV GRENOBLE ALPES   (France)

Author keywords

Amphiphilic cyclodextrins; Emulsification evaporation method; Nanospheres; Progesterone

Indexed keywords

AMPHOPHILE; CYCLODEXTRIN DERIVATIVE; NANOPARTICLE; POLOXAMER; PROGESTERONE; SURFACTANT;

ARTICLE; EVAPORATION; MICELLE; PRIORITY JOURNAL;

EID: 0032143015     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(98)00147-1     Document Type: Article

References (18)

1. Allémann, E., Gurny, R., Doelker, E., 1992. Preparation of aqueous polymeric nanodispersions by a reversible salting-out process: influence of process parameters on particle size. Int. J. Pharm. 87, 247-253.
2. Allémann, E., Leroux, J.C., Gurny, R., Doelker, E., 1993. In vitro extended-release properties of drug-loaded poly(DL-Lactide Acid) nanoparticles produced by salting-out procedure. Pharm. Res. 10, 1732-1737.
3. Al-Saden, A.A., Whateley, T.L., Florence, A.T., 1982. Polaxamer Association in aqueous solution. J. Colloid Interface Sci. 90, 303-309.
4. Bodmeier, R., Chen, H., 1990. Indomethacin polymeric nanosuspensions prepared by microfluidization. J. Controlled Release 12, 223-233.
5. Bodmeier, R., McGinity, J.W., 1987a. Polylactide acid microspheres containing quinidine base and quinidine sulphate prepared by solvent evaporation technique. I. Methods and morphology. J. Microencapsulation 4, 279-288.
6. Bodmeier, R., McGinity, J.W., 1987b. Polylactide acid microspheres containing quinidine base and quinidine sulphate prepared by solvent evaporation technique. II. Some process parameters influencing the preparation and properties of microspheres. J. Microencapsulation 4, 289-297.
7. Bodmeier, R., McGinity, J.W., 1988. Solvent selection in the preparation of poly(DL-lactide) microspheres prepared by the solvent evaporation method. Int. J. Pharm. 43, 179-186.
8. Fessi, H., Puisieux, F., Devissaguet, J.-P., 1988. Procédé de préparation de systèmes colloïdaux dispersibles d'une substance sous forme de nanosphères. US Patent No. 5118,528.
9. Jeffery, H., Davis, S.S., O'Hagan, 1991. The preparation and characterisation of poly(lactide-co-glycolide) microparticles. I: Oil-in-water emulsion solvent evaporation. Int. J. Pharm. 77, 169-175.
10. Kataoka, K., Kwon, G., Yokoyama, M., Okano, T., Sakurai, Y., 1993. Block copolymer micelles as vehicles for drug delivery. J. Controlled Release 24, 119-132.
11. Lemos-Senna, E., Wouessidjewe, D., Duchêne, D., Lesieur, S., 1998. Amphiphilic cyclodextrin nanospheres: particle solubilization and reconstitution by action of a non-ionic detergent. Colloids and Surfaces B: Biointerfaces 10, 291-301.
12. Lemos-Senna, E., Wouessidjewe, D., Lesieur, S., Puisieux, F., Couarraze, G., Duchêne, D., 1998a. Evaluation of the hydrophobic drug loading characteristics in nanoprecipitated amphiphilic cyclodextrins nanospheres. Pharm. Develop. Tech. 3, 85-94.
13. Leroux, J.-C., Allémann, E., Doelker, E., Gurny, R., 1995. New approach for the preparation of nanoparticles by an emulsification-diffusion method. Eur. J. Biopharm. 41, 14-18.
14. Niwa, T., Takeuchi, H., Hino, T., Kunou, N., Kawashima, Y., 1993. Preparations of biodegradable nanospheres of water-soluble and insoluble drugs by a novel spontaneous emulsification solvent diffusion method, and drug release behavior. J. Controlled Release 25, 89-98.
15. Puisieux, F., Barratt, G., Couarraze, G., Couvreur, P., Devissaguet, J.-P., Dubernet, C., Fattal, E., Fessi, H., Vauthier, C., Benita, S., 1994. Polymeric Micro- and Nanoparticles as Drug Carriers. In: Dumitriu, S. (Ed.), Polymeric Biomaterials. Marcel Dekker, New York, pp. 749-794.
16. Topchieva, I.N., Blumenfeld, A.L., Polyakov, V.A., Klyamkin, A.A., 25-28 April 1994. Complexation between Cyclodextrins and Pluronics. In: Proc. 7th Int. Cyclodextrins Symposium, Tokyo, Komiyama Printing, Bunkyo-ku, Tokyo, pp. 262-265.
17. Ueda, M., Kreuter, J., 1997. Optimization of the preparation of loperamide-loaded poly (L-lactide) nanoparticles by high pressure emulsification-solvent evaporation. J. Microencapsulation 14, 593-605.
18. Zhang, P., Ling, C.-C., Coleman, A., Parrot-Lopez, H., Galons, H., 1991. Formation of amphiphilic cyclodextrins via hydrophobic esterification at the secondary hydroxyl face. Tetrahedron Lett. 32, 2769-2770.