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Volumn 100, Issue 12, 2009, Pages 2309-2317

Tumor-stromal interactions with direct cell contacts enhance proliferation of human pancreatic carcinoma cells

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; GREEN FLUORESCENT PROTEIN; NERVE CELL ADHESION MOLECULE; NOTCH RECEPTOR; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR SNAIL; VIMENTIN;

EID: 70649095047     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2009.01317.x     Document Type: Article
Times cited : (68)

References (48)
  • 1
    • 17144404527 scopus 로고    scopus 로고
    • Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells
    • Bachem MG, Schunemann M, Ramadani M. Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells. Gastroenterology 2005, 128:907-21.
    • (2005) Gastroenterology , vol.128 , pp. 907-921
    • Bachem, M.G.1    Schunemann, M.2    Ramadani, M.3
  • 2
    • 34648852355 scopus 로고    scopus 로고
    • Pancreatic cancer-associated stroma production
    • Korc M. Pancreatic cancer-associated stroma production. Am J Surg 2007, 194:S84-6.
    • (2007) Am J Surg , vol.194
    • Korc, M.1
  • 3
    • 0036186862 scopus 로고    scopus 로고
    • Myofibroblasts are responsible for the desmoplastic reaction surrounding human pancreatic carcinomas
    • Yen TW, Aardal NP, Bronner MP. Myofibroblasts are responsible for the desmoplastic reaction surrounding human pancreatic carcinomas. Surgery 2002, 131:129-34.
    • (2002) Surgery , vol.131 , pp. 129-134
    • Yen, T.W.1    Aardal, N.P.2    Bronner, M.P.3
  • 4
    • 8444244417 scopus 로고    scopus 로고
    • Type I collagen promotes the malignant phenotype of pancreatic ductal adenocarcinoma
    • Armstrong T, Packham G, Murphy LB. Type I collagen promotes the malignant phenotype of pancreatic ductal adenocarcinoma. Clin Cancer Res 2004, 10:7427-37.
    • (2004) Clin Cancer Res , vol.10 , pp. 7427-7437
    • Armstrong, T.1    Packham, G.2    Murphy, L.B.3
  • 5
    • 0035504739 scopus 로고    scopus 로고
    • Gene expression profiles of pancreatic cancer and stromal desmoplasia
    • Crnogorac-Jurcevic T, Efthimiou E, Capelli P. Gene expression profiles of pancreatic cancer and stromal desmoplasia. Oncogene 2001, 20:7437-46.
    • (2001) Oncogene , vol.20 , pp. 7437-7446
    • Crnogorac-Jurcevic, T.1    Efthimiou, E.2    Capelli, P.3
  • 6
    • 33646428351 scopus 로고    scopus 로고
    • Collagen type I induces disruption of E-cadherin-mediated cell-cell contacts and promotes proliferation of pancreatic carcinoma cells
    • Koenig A, Mueller C, Hasel C, Adler G, Menke A. Collagen type I induces disruption of E-cadherin-mediated cell-cell contacts and promotes proliferation of pancreatic carcinoma cells. Cancer Res 2006, 66:4662-71.
    • (2006) Cancer Res , vol.66 , pp. 4662-4671
    • Koenig, A.1    Mueller, C.2    Hasel, C.3    Adler, G.4    Menke, A.5
  • 7
    • 34248141223 scopus 로고    scopus 로고
    • Tumor-stroma interactions in pancreatic ductal adenocarcinoma
    • Mahadevan D, Von Hoff DD. Tumor-stroma interactions in pancreatic ductal adenocarcinoma. Mol Cancer Ther 2007, 6:1186-97.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1186-1197
    • Mahadevan, D.1    Von Hoff, D.D.2
  • 8
    • 4644317795 scopus 로고    scopus 로고
    • Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells
    • Apte MV, Park S, Phillips PA. Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells. Pancreas 2004, 29:179-87.
    • (2004) Pancreas , vol.29 , pp. 179-187
    • Apte, M.V.1    Park, S.2    Phillips, P.A.3
  • 9
    • 0037381404 scopus 로고    scopus 로고
    • Immunocytes and activated stellate cells in pancreatic fibrogenesis
    • Jaskiewicz K, Nalecz A, Rzepko R, Sledzinski Z. Immunocytes and activated stellate cells in pancreatic fibrogenesis. Pancreas 2003, 26:239-42.
    • (2003) Pancreas , vol.26 , pp. 239-242
    • Jaskiewicz, K.1    Nalecz, A.2    Rzepko, R.3    Sledzinski, Z.4
  • 10
    • 0035863426 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 induces desmoplasia in an experimental model of human pancreatic carcinoma
    • Lohr M, Schmidt C, Ringel J. Transforming growth factor-beta1 induces desmoplasia in an experimental model of human pancreatic carcinoma. Cancer Res 2001, 61:550-5.
    • (2001) Cancer Res , vol.61 , pp. 550-555
    • Lohr, M.1    Schmidt, C.2    Ringel, J.3
  • 11
    • 4644309325 scopus 로고    scopus 로고
    • Pancreatic cancer stimulates pancreatic stellate cell proliferation and TIMP-1 production through the MAP kinase pathway
    • Yoshida S, Yokota T, Ujiki M. Pancreatic cancer stimulates pancreatic stellate cell proliferation and TIMP-1 production through the MAP kinase pathway. Biochem Biophys Res Commun 2004, 323:1241-5.
    • (2004) Biochem Biophys Res Commun , vol.323 , pp. 1241-1245
    • Yoshida, S.1    Yokota, T.2    Ujiki, M.3
  • 12
    • 0032829703 scopus 로고    scopus 로고
    • Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis
    • Haber PS, Keogh GW, Apte MV. Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis. Am J Pathol 1999, 155:1087-95.
    • (1999) Am J Pathol , vol.155 , pp. 1087-1095
    • Haber, P.S.1    Keogh, G.W.2    Apte, M.V.3
  • 13
    • 38849141696 scopus 로고    scopus 로고
    • Cancer-associated stromal fibroblasts promote pancreatic tumor progression
    • Hwang RF, Moore T, Arumugam T. Cancer-associated stromal fibroblasts promote pancreatic tumor progression. Cancer Res 2008, 68:918-26.
    • (2008) Cancer Res , vol.68 , pp. 918-926
    • Hwang, R.F.1    Moore, T.2    Arumugam, T.3
  • 14
    • 42049097658 scopus 로고    scopus 로고
    • Pancreatic stellate cells: partners in crime with pancreatic cancer cells
    • Vonlaufen A, Joshi S, Qu C. Pancreatic stellate cells: partners in crime with pancreatic cancer cells. Cancer Res 2008, 68:2085-93.
    • (2008) Cancer Res , vol.68 , pp. 2085-2093
    • Vonlaufen, A.1    Joshi, S.2    Qu, C.3
  • 16
    • 0025103317 scopus 로고
    • Fibroblast-mediated acceleration of human epithelial tumor growth in vivo
    • Camps JL, Chang SM, Hsu TC. Fibroblast-mediated acceleration of human epithelial tumor growth in vivo. Proc Natl Acad Sci U S A 1990, 87:75-9.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 75-79
    • Camps, J.L.1    Chang, S.M.2    Hsu, T.C.3
  • 17
    • 1842687362 scopus 로고    scopus 로고
    • Reconstruction of functionally normal and malignant human breast tissues in mice
    • Kuperwasser C, Chavarria T, Wu M. Reconstruction of functionally normal and malignant human breast tissues in mice. Proc Natl Acad Sci U S A 2004, 101:4966-71.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4966-4971
    • Kuperwasser, C.1    Chavarria, T.2    Wu, M.3
  • 18
    • 2342640981 scopus 로고    scopus 로고
    • Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions
    • Ohuchida K, Mizumoto K, Murakami M. Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions. Cancer Res 2004, 64:3215-22.
    • (2004) Cancer Res , vol.64 , pp. 3215-3222
    • Ohuchida, K.1    Mizumoto, K.2    Murakami, M.3
  • 19
    • 34250863385 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling in prostate stromal cells supports prostate carcinoma growth by up-regulating stromal genes related to tissue remodeling
    • Verona EV, Elkahloun AG, Yang J, Bandyopadhyay A, Yeh IT, Sun LZ. Transforming growth factor-beta signaling in prostate stromal cells supports prostate carcinoma growth by up-regulating stromal genes related to tissue remodeling. Cancer Res 2007, 67:5737-46.
    • (2007) Cancer Res , vol.67 , pp. 5737-5746
    • Verona, E.V.1    Elkahloun, A.G.2    Yang, J.3    Bandyopadhyay, A.4    Yeh, I.T.5    Sun, L.Z.6
  • 20
    • 33750798741 scopus 로고    scopus 로고
    • The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis
    • Yang G, Rosen DG, Zhang Z. The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis. Proc Natl Acad Sci U S A 2006, 103:16472-7.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 16472-16477
    • Yang, G.1    Rosen, D.G.2    Zhang, Z.3
  • 21
    • 33744979500 scopus 로고    scopus 로고
    • Collagen-based co-culture for invasive study on cancer cells-fibroblasts interaction
    • Che ZM, Jung TH, Choi JH. Collagen-based co-culture for invasive study on cancer cells-fibroblasts interaction. Biochem Biophys Res Commun 2006, 346:268-75.
    • (2006) Biochem Biophys Res Commun , vol.346 , pp. 268-275
    • Che, Z.M.1    Jung, T.H.2    Choi, J.H.3
  • 22
    • 0037603123 scopus 로고    scopus 로고
    • To create the correct microenvironment: three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia
    • Gudjonsson T, Ronnov-Jessen L, Villadsen R, Bissell MJ, Petersen OW. To create the correct microenvironment: three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia. Methods 2003, 30:247-55.
    • (2003) Methods , vol.30 , pp. 247-255
    • Gudjonsson, T.1    Ronnov-Jessen, L.2    Villadsen, R.3    Bissell, M.J.4    Petersen, O.W.5
  • 23
    • 0033981031 scopus 로고    scopus 로고
    • Co-culture with human fibroblasts increases the radiosensitivity of MCF-7 mammary carcinoma cells in collagen gels
    • Rossi L, Reverberi D, Podesta G, Lastraioli S, Corvo R. Co-culture with human fibroblasts increases the radiosensitivity of MCF-7 mammary carcinoma cells in collagen gels. Int J Cancer 2000, 85:667-73.
    • (2000) Int J Cancer , vol.85 , pp. 667-673
    • Rossi, L.1    Reverberi, D.2    Podesta, G.3    Lastraioli, S.4    Corvo, R.5
  • 24
    • 0041622897 scopus 로고    scopus 로고
    • Three-dimensional coculture of endometrial cancer cells and fibroblasts in human placenta derived collagen sponges and expression matrix metalloproteinases in these cells
    • Tanaka R, Saito T, Ashihara K, Nishimura M, Mizumoto H, Kudo R. Three-dimensional coculture of endometrial cancer cells and fibroblasts in human placenta derived collagen sponges and expression matrix metalloproteinases in these cells. Gynecol Oncol 2003, 90:297-304.
    • (2003) Gynecol Oncol , vol.90 , pp. 297-304
    • Tanaka, R.1    Saito, T.2    Ashihara, K.3    Nishimura, M.4    Mizumoto, H.5    Kudo, R.6
  • 25
    • 0038189215 scopus 로고    scopus 로고
    • Effect of stromal and epithelial cells derived from normal and tumorous breast tissue on the proliferation of human breast cancer cell lines in co-culture
    • Dong-Le Bourhis X, Berthois Y, Millot G. Effect of stromal and epithelial cells derived from normal and tumorous breast tissue on the proliferation of human breast cancer cell lines in co-culture. Int J Cancer 1997, 71:42-8.
    • (1997) Int J Cancer , vol.71 , pp. 42-48
    • Dong-Le Bourhis, X.1    Berthois, Y.2    Millot, G.3
  • 26
    • 10744221950 scopus 로고    scopus 로고
    • Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta
    • Muerkoster S, Wegehenkel K, Arlt A. Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta. Cancer Res 2004, 64:1331-7.
    • (2004) Cancer Res , vol.64 , pp. 1331-1337
    • Muerkoster, S.1    Wegehenkel, K.2    Arlt, A.3
  • 27
    • 0037428875 scopus 로고    scopus 로고
    • Co-cultivation of pancreatic cancer cells with orthotopic tumor-derived fibroblasts: fibroblasts stimulate tumor cell invasion via HGF secretion whereas cancer cells exert a minor regulative effect on fibroblasts HGF production
    • Qian LW, Mizumoto K, Maehara N. Co-cultivation of pancreatic cancer cells with orthotopic tumor-derived fibroblasts: fibroblasts stimulate tumor cell invasion via HGF secretion whereas cancer cells exert a minor regulative effect on fibroblasts HGF production. Cancer Lett 2003, 190:105-12.
    • (2003) Cancer Lett , vol.190 , pp. 105-112
    • Qian, L.W.1    Mizumoto, K.2    Maehara, N.3
  • 28
    • 0042284883 scopus 로고    scopus 로고
    • SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions
    • Sato N, Fukushima N, Maehara N. SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions. Oncogene 2003, 22:5021-30.
    • (2003) Oncogene , vol.22 , pp. 5021-5030
    • Sato, N.1    Fukushima, N.2    Maehara, N.3
  • 29
    • 4944265244 scopus 로고    scopus 로고
    • Gene expression profiling of tumor-stromal interactions between pancreatic cancer cells and stromal fibroblasts
    • Sato N, Maehara N, Goggins M. Gene expression profiling of tumor-stromal interactions between pancreatic cancer cells and stromal fibroblasts. Cancer Res 2004, 64:6950-6.
    • (2004) Cancer Res , vol.64 , pp. 6950-6956
    • Sato, N.1    Maehara, N.2    Goggins, M.3
  • 30
    • 31544479046 scopus 로고    scopus 로고
    • The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms
    • Bavik C, Coleman I, Dean JP, Knudsen B, Plymate S, Nelson PS. The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms. Cancer Res 2006, 66:794-802.
    • (2006) Cancer Res , vol.66 , pp. 794-802
    • Bavik, C.1    Coleman, I.2    Dean, J.P.3    Knudsen, B.4    Plymate, S.5    Nelson, P.S.6
  • 31
    • 0035341347 scopus 로고    scopus 로고
    • The influence of autologous tumor fibroblasts on the radiosensitivity of squamous cell carcinoma megacolonies
    • Kummermehr J, Malinen E, Freykowski S, Sund M, Trott KR. The influence of autologous tumor fibroblasts on the radiosensitivity of squamous cell carcinoma megacolonies. Int J Radiat Oncol Biol Phys 2001, 50:229-37.
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , pp. 229-237
    • Kummermehr, J.1    Malinen, E.2    Freykowski, S.3    Sund, M.4    Trott, K.R.5
  • 32
    • 26844529911 scopus 로고    scopus 로고
    • Clonogenic growth of human breast cancer cells co-cultured in direct contact with serum-activated fibroblasts
    • Samoszuk M, Tan J, Chorn G. Clonogenic growth of human breast cancer cells co-cultured in direct contact with serum-activated fibroblasts. Breast Cancer Res 2005, 7:R274-83.
    • (2005) Breast Cancer Res , vol.7
    • Samoszuk, M.1    Tan, J.2    Chorn, G.3
  • 33
    • 0036782805 scopus 로고    scopus 로고
    • Quantification of epithelial cells in coculture with fibroblasts by fluorescence image analysis
    • Krtolica A, Ortiz de Solorzano C, Lockett S, Campisi J. Quantification of epithelial cells in coculture with fibroblasts by fluorescence image analysis. Cytometry 2002, 49:73-82.
    • (2002) Cytometry , vol.49 , pp. 73-82
    • Krtolica, A.1    Ortiz de Solorzano, C.2    Lockett, S.3    Campisi, J.4
  • 34
    • 0035834121 scopus 로고    scopus 로고
    • Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging
    • Krtolica A, Parrinello S, Lockett S, Desprez PY, Campisi J. Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc Natl Acad Sci U S A 2001, 98:12072-7.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12072-12077
    • Krtolica, A.1    Parrinello, S.2    Lockett, S.3    Desprez, P.Y.4    Campisi, J.5
  • 37
    • 0037022980 scopus 로고    scopus 로고
    • Fluorescent proteins in animal cells for process development: optimization of sodium butyrate treatment as an example
    • Hunt L, Batard P, Jordan M, Wurm FM. Fluorescent proteins in animal cells for process development: optimization of sodium butyrate treatment as an example. Biotechnol Bioeng 2002, 77:528-37.
    • (2002) Biotechnol Bioeng , vol.77 , pp. 528-537
    • Hunt, L.1    Batard, P.2    Jordan, M.3    Wurm, F.M.4
  • 38
    • 0033589372 scopus 로고    scopus 로고
    • GFP-expressing mammalian cells for fast, sensitive, noninvasive cell growth assessment in a kinetic mode
    • Hunt L, Jordan M, De Jesus M, Wurm FM. GFP-expressing mammalian cells for fast, sensitive, noninvasive cell growth assessment in a kinetic mode. Biotechnol Bioeng 1999, 65:201-5.
    • (1999) Biotechnol Bioeng , vol.65 , pp. 201-205
    • Hunt, L.1    Jordan, M.2    De Jesus, M.3    Wurm, F.M.4
  • 39
    • 5444247172 scopus 로고    scopus 로고
    • Identification, culture, and characterization of pancreatic stellate cells in rats and humans
    • Bachem MG, Schneider E, Gross H. Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology 1998, 115:421-32.
    • (1998) Gastroenterology , vol.115 , pp. 421-432
    • Bachem, M.G.1    Schneider, E.2    Gross, H.3
  • 40
    • 0032974472 scopus 로고    scopus 로고
    • Quantitative determination of apoptotic death in cultured human pancreatic cancer cells by propidium iodide and digitonin
    • Zhang L, Mizumoto K, Sato N. Quantitative determination of apoptotic death in cultured human pancreatic cancer cells by propidium iodide and digitonin. Cancer Lett 1999, 142:129-37.
    • (1999) Cancer Lett , vol.142 , pp. 129-137
    • Zhang, L.1    Mizumoto, K.2    Sato, N.3
  • 41
    • 16844380271 scopus 로고    scopus 로고
    • Quantitative assessment of telomerase activity and human telomerase reverse transcriptase messenger RNA levels in pancreatic juice samples for the diagnosis of pancreatic cancer
    • Ohuchida K, Mizumoto K, Ogura Y. Quantitative assessment of telomerase activity and human telomerase reverse transcriptase messenger RNA levels in pancreatic juice samples for the diagnosis of pancreatic cancer. Clin Cancer Res 2005, 11:2285-92.
    • (2005) Clin Cancer Res , vol.11 , pp. 2285-2292
    • Ohuchida, K.1    Mizumoto, K.2    Ogura, Y.3
  • 42
    • 34247236139 scopus 로고    scopus 로고
    • Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity
    • Erkan M, Kleeff J, Gorbachevski A. Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity. Gastroenterology 2007, 132:1447-64.
    • (2007) Gastroenterology , vol.132 , pp. 1447-1464
    • Erkan, M.1    Kleeff, J.2    Gorbachevski, A.3
  • 43
    • 0043172396 scopus 로고    scopus 로고
    • Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
    • Grunert S, Jechlinger M, Beung H. Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nature Rev Mol Cell Biol 2003, 4:657-65.
    • (2003) Nature Rev Mol Cell Biol , vol.4 , pp. 657-665
    • Grunert, S.1    Jechlinger, M.2    Beung, H.3
  • 44
    • 65249147725 scopus 로고    scopus 로고
    • Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer
    • Mullendore ME, Koorstra JB, Li YM. Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer. Clin Cancer Res 2009, 15:2291-301.
    • (2009) Clin Cancer Res , vol.15 , pp. 2291-2301
    • Mullendore, M.E.1    Koorstra, J.B.2    Li, Y.M.3
  • 45
    • 65249125270 scopus 로고    scopus 로고
    • Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma
    • e6
    • Plentz R, Park JS, Rhim AD. Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma. Gastroenterology 2009, 136:1741-9. e6
    • (2009) Gastroenterology , vol.136 , pp. 1741-1749
    • Plentz, R.1    Park, J.S.2    Rhim, A.D.3
  • 46
    • 33645049305 scopus 로고    scopus 로고
    • Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells
    • Wang Z, Banerjee S, Li Y, Rahman KM, Zhang Y, Sarkar FH. Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells. Cancer Res 2006, 66:2778-84.
    • (2006) Cancer Res , vol.66 , pp. 2778-2784
    • Wang, Z.1    Banerjee, S.2    Li, Y.3    Rahman, K.M.4    Zhang, Y.5    Sarkar, F.H.6
  • 47
    • 33646877856 scopus 로고    scopus 로고
    • Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells
    • Wang Z, Zhang Y, Banerjee S, Li Y, Sarkar FH. Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells. Cancer 2006, 106:2503-13.
    • (2006) Cancer , vol.106 , pp. 2503-2513
    • Wang, Z.1    Zhang, Y.2    Banerjee, S.3    Li, Y.4    Sarkar, F.H.5
  • 48
    • 65649134362 scopus 로고    scopus 로고
    • Notch1 signaling in FIZZ1 induction of myofibroblast differentiation
    • Liu T, Hu B, Choi YY. Notch1 signaling in FIZZ1 induction of myofibroblast differentiation. Am J Pathol 2009, 174:1745-55.
    • (2009) Am J Pathol , vol.174 , pp. 1745-1755
    • Liu, T.1    Hu, B.2    Choi, Y.Y.3


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