Erythropoietin inhibits liver gelatinases during galactosamine-induced hepatic damage in rats

Pharmacological Reports

Volumn 61, Issue 5, 2009, Pages 917-923

  Ma̧dro, Agnieszka ^a   Kurzepa, Jacek ^a   Czechowska, Grazyna ^a   Słomka, Maria ^a   Celiński, Krzysztof ^a   Szymonik Lesiuk, Stanisława ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Erythropoietin; Galactosamine; Gelatinases; Liver; MMP 2; MMP 9; Rats

Indexed keywords

ERYTHROPOIETIN; GALACTOSAMINE; GELATINASE; GELATINASE A; GELATINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INHIBITION; LIVER INJURY; LIVER PROTECTION; NONHUMAN; RAT; SINGLE DRUG DOSE; ZYMOGRAPHY;

EID: 70549111195     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(09)70149-5     Document Type: Article

References (27)

1. Abdel Salam OM, Baiuomy AR, El-Shenawy SM, Hassan NS: Effect of pentoxifylline on hepatic injury caused in the rat by the administration of carbon tetrachloride or acetaminophen. Pharmacol Rep, 2005, 57, 596-603.
2. Chan CY, Chen YS, Lee HH, Huang HS, Lai YL, Chen CF, Ma MC: Erythropoietin protects post-ischemic hearts by preventing extracellular matrix degradation: role of Jak2-ERK pathway. Life Sci, 2007, 9, 717-723.
3. Chandler S, Miller KM, Clemens JM, Lury J, Corkill D, Anthony DC, Adams SE, Gearing AJ: Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: an overview. J Neuroimmunol, 1997, 72, 155-161. (Pubitemid 27062771)
4. Defamie V, Laurens M, Patrono D, Devel L, Brault A, Saint-Paul MC, Yiotakis A et al.: Matrix metalloproteinase inhibition protects rat livers from prolonged cold ischemia-warm reperfusion injury. Hepatology, 2008, 47, 177-185. (Pubitemid 351171055)
5. El-Shenawy SM, Hassan NS: Comparative evaluation of the protective effect of selenium and garlic against liver and kidney damage induced by mercury chloride in the rats. Pharmacol Rep, 2008, 60, 199-208.
6. Ferenčikowá R, Červinková Z, Drahota Z: Hepatotoxic effect of D-galactosamine and protective role of lipid emulsion. Physiol Res, 2003, 52, 73-78. (Pubitemid 36356263)
7. Gressner OA, R.Weiskirchen R, Gressner AM: Biomarkers of hepatic fibrosis, fibrogenesis and genetic predisposition pending between fiction and reality. J Cell Mol Med Vol, 2007, 11, 1031-1051.
8. Guo J, Friedman SL: Hepatic fibrogenesis. Semin Liver Dis, 2007, 27, 413-426.
9. Hamada T, Fondevila C, Busuttil RW, Coito AJ: Metalloproteinase-9 deficiency protects against hepatic ischemia/reperfusion injury. Hepatology, 2008, 47, 186-198. (Pubitemid 351171056)
10. Han YP, Yan C, Zhou L, Qin L, Tsukamoto H: A matrix metalloproteinase-9 activation cascade by hepatic stellate cells in trans-differentiation in the three-dimentional extracellular matrix. J Biol Chem, 2007, 27, 12928-12939.
11. Hrabec E, Naduk J, Strek M, Hrabec Z: Type IV collagenases (MMP-2 and MMP-9) and their substrates-intracellular proteins, hormones, cytokines, chemokines and their receptors (in Polish). Postȩpy Biochem, 2007, 53, 37-45.
12. Joyeux-Faure M: Cellular protection by erythropoietin: new terapeutic implication? J Pharmacol Exp Ther, 2007, 323, 759-762.
13. Kadri Z, Petitfrère E, Boudot C, Freyssinier JM, Fichelson S, Mayeux P, Emonard H et al.: Erythropoietin induction of tissue inhibitors of metalloproteinase-1 expression and secretion is mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways. Cell Growth Differ, 2000, 11, 573-580
14. Keppler D, Pausch J, Decher K: Selective uridine triphosphate deficiency induced by D-galactosamine in liver and reversed by pyrimidine nucleotide precursors. Effect on ribonucleic acid syntesis. J Biol Chem, 1974, 249, 211-216.
15. Kmieć Z, Marlewski M, Smolewski RT, Simmons HA: Effect of galactosamine on adenine and uracyl nucleotides levels in isolated hepatocytes of young and old rats. In: Purine and Pyrimidine metabolism in Man. Vol.VIII, Ed. Sabota A, Taylor M, Plenum Press, New York, 1995, 523-526.
16. Kurzepa J, Stryjecka-Zimmer M: The effect of interferon β-1a on MMP-2 and MMP-9 proteolytic activity. Folia Biol (Praha), 2007, 53, 220-221. (Pubitemid 350285055)
17. Le Minh K, Klemm K, Abshagen K, Eipel C, Menger MD, Vollmar B: Attenuation of inflammation and apoptosis by pre- and posttreatment of darbepoetin-α in acute liver failure of mice. Am J Pathol, 2007, 170, 1954-1963.
18. Nangaku M, Fliser D: Erythropoiesis-stimulating agents: past and future. Kidney Int Suppl, 2007, 107, 1-3.
19. Nishiya D, Omura T, Shimada K, Matsumoto R, Kusuyama T, Enomoto S, Iwao H et al.: Effects of erythropoietin on cardiac remodeling after myocardial infarction. J Pharmacol Sci, 2006, 101, 31-39. (Pubitemid 43765334)
20. Sasaki R: Pleiotropic functions of erythropoietin. Intern Med, 2003, 42, 142-149.
21. Schmeding M, Neuman UP, Baas-Knoop S, Spinelli A, Neuhaus P: Erythropoetin reduces ischemia- reperfusion injuring in the rat liver. Eur Surg Res, 2007, 39, 189-197.
22. Sepodes B, Maio R, Pinto R, Sharples E, Oliveira P, McDonald M, Yaqoob M et al.: Recombinant human erythropoietin protects the liver from hepatic ischemia-reperfusion injury in the rats. Transpl Int, 2006, 19, 919-926. (Pubitemid 44511117)
23. Theret N, Lehti K, Musso O, Clement B: MMP-2 activation by collagen I and concanavalin A in cultured human hepatic stellate cells. Hepatology, 1999, 30, 462-468. (Pubitemid 29357512)
24. Yan C, Zhou L, Han YP: Contribution of hepatic stellate cells and matrix metalloproteinase 9 in acute liver failure. Liver Int, 2008, 26, 959-971.
25. Zhang JW, Gottschall PE: Zymographic measurement of gelatinase activity in brain tissue after detergent extraction and affinity-support purification. J Neurosci Methods, 1997, 76, 15-20.
26. Zhang LJ, Zheng WD, Chen YX, Huang YH, Chen ZX, Zhang SJ, Shi MN, Wang XZ: Antifibrotic effects of interleukin-10 on experimental hepatic fibrosis. Hepatogastroenterology, 2007, 79, 2092-2098.
27. Zhen MC, Huang XH, Wang Q, Sun K, Liu YJ, Li W, Zhang LJ et al.: Green tea polyphenol epigallocatechin-3-gallate suppresses rat hepatic stellate cell activation by inhibition of MMP-2 expression and its activation. Acta Pharmacol Sin, 2006, 27, 1600-1607. (Pubitemid 44813898)