The effect of interferon β-1a on MMP-2 and MMP-9 proteolytic activity

Folia Biologica

Volumn 53, Issue 6, 2007, Pages 220-221

  Kurzepa, Jacek ^a   Stryjecka Zimmer, M ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

IFN 1a; MMP 2; MMP 9; Zymography

Indexed keywords

BETA INTERFERON; BETA1A INTERFERON; GELATINASE A; GELATINASE B;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; GEL ELECTROPHORESIS; HUMAN; MALE; NORMAL HUMAN; PROTEIN DEGRADATION; ZYMOGRAPHY;

EID: 37349062042     PISSN: 00155500     EISSN: 25337602     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Avolio, C., Ruggieri, M., Giuliani, F., Liuzzi, G. M., Leante, R., Ricco, P., Livrea, P., Trojano, M. (2003) Serum MMP-2 and MMP-9 are elevated in different multiple sclerosis subtypes. J. Neuroimmunol. 136, 46-53.
2. Avolio, C., Filippi, M., Tortorella, C., Rocca, M. A., Ruggieri, M., Agosta, F., Tomassini, V., Pozzilli, C., Stecchi, S., Giaquinto, P., Livrea, P., Trojano, M. (2005) Serum MMP-9/TIMP-1 and MMP-2/TIMP-2 ratios in multiple sclerosis: relationships with different magnetic resonance imaging measures of disease activity during IFN-β-1a treatment. Mult. Scler. 11, 441-446.
3. Azeh, I., Mäder, M., Smirnov, A., Beuche, W., Nau, R., Weber, F. (1998) Experimental pneumococcal meningitis in rabbits: the increase of matrix metalloproteinase-9 in cerebrospinal fluid correlates with leucocyte invasion. Neurosci. Lett. 256, 127-130.
4. Bar-Or, A., Oliveira, E. M., Anderson D. E., Hafler, D. A. (1999) Molecular pathogenesis of multiple sclerosis. J. Neuroimmunol. 100, 252-259.
5. Chandler, S., Miller, K. M., Clements, J. M., Lury, J., Corkill, D., Anthony, D. C., Adams, S. E., Gearing, A. J. (1997) Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: an overview. J. Neuroimmunol. 72, 155-161.
6. Hartung, H. P., Kieseier, B. C. (2000) The role of matrix metalloproteinases in autoimmune damage to the central and peripheral nervous system. J. Neuroimmunol. 107, 140-147.
7. Kieseier, B. C., Hartung, H. P. (2004) Different effects of simvastin and interferon β on the proteolytic activity of matrix metalloproteinases. Arch. Neurol. 61, 929-932.
8. Opdenakker, G., Van den Steen, P. E., Van Damme, J. (2001) Gelatinase B: a tuner and amplifier of immune functions. Trends Immunol. 22, 571-579.