Estrogen prevents norepinephrine alpha-2a receptor reversal of stress-induced working memory impairment

Stress

Volumn 12, Issue 5, 2009, Pages 457-463

  Shansky, Rebecca M ^a   Bender, Genevieve ^b   Arnsten, A F T ^b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acute stress; Estrogen; Norepinephrine; Prefrontal cortex; Sex differences; Working memory

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; BUPRENORPHINE; ESTRADIOL; GUANFACINE; N METHYL BETA CARBOLINE 3 CARBOXAMIDE;

ACUTE STRESS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; CONTROLLED STUDY; ESTROGEN THERAPY; FEMALE; HABITUATION; MAZE TEST; MEMORY DISORDER; MENTAL STRESS; NEUROPROTECTION; NONHUMAN; OVARIECTOMY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEX DIFFERENCE; TASK PERFORMANCE; WESTERN BLOTTING; WORKING MEMORY;

ANIMALS; CARBOLINES; ESTROGEN REPLACEMENT THERAPY; ESTROGENS; FEMALE; GUANFACINE; MEMORY DISORDERS; MEMORY, SHORT-TERM; OVARIECTOMY; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2; STRESS, PSYCHOLOGICAL;

EID: 70549099013     PISSN: 10253890     EISSN: 16078888     Source Type: Journal    
DOI: 10.1080/10253890802520988     Document Type: Article

References (44)

1. Ansonoff MA, Etgen AM. 2001. Receptor phosphorylation mediates estradiol reduction of alpha2-adrenoceptor coupling to G protein in the hypothalamus of female rats. Endocrine 14: 165-174.
2. Aoki C, Venkatesan C, Go C-G, Forman R, Kurose H. 1998. Cellular and subcellular sites for noradrenergic action in the monkey dorsolateral prefrontal cortex as revealed by the immunocytochemical localization of noradrenergic receptors and axons. Cerebral Cortex 8:269-277.
3. Arnsten AF. 2007. Catecholamine and second messenger influences on prefrontal cortical networks of "representational knowledge": A rational bridge between genetics and the symptoms of mental illness. Cereb Cortex 17(Suppl 1):i6-15.
4. Arnsten AFT, Goldman-Rakic PS. 1990. Stress impairs prefrontal cortex cognitive function in monkeys: Role of dopamine. Soc Neurosci Abstr 16:164.
5. Arnsten AFT, Goldman-Rakic PS. 1998. Noise stress impairs prefrontal cortical cognitive function in monkeys: Evidence for a hyperdopaminergic mechanism. Arch Gen Psychiatry 55: 362-369.
6. Birnbaum SG, Gobeske KT, Auerbach J, Taylor JR, Arnsten AFT. 1999. A role for norepinephrine in stress-induced cognitive deficits: Alpha-1-adrenoceptor mediation in prefrontal cortex. Biol Psychiatry 46:1266-1274.
7. Birnbaum SG, Podell DM, Arnsten AFT. 2000. Noradrenergic alpha-2 receptor agonists reverse working memory deficits induced by the anxiogenic drug, FG7142, in rats. Pharmacol Biochem Behav 67:397-403.
8. Botteron KN, Raichle ME, Drevets WC, Heath AC, Todd RD. 2002. Volumetric reduction in left subgenual prefrontal cortex in early onset depression. Biol Psychiatry 51:342-344.
9. Bowman RE, Zrull MC, Luine VN. 2001. Chronic restraint stress enhances radial arm maze performance in female rats. Brain Res 904:279-289.
10. Bowman RE, Ferguson D, Luine VN. 2002. Effects of chronic restraint stress and estradiol on open field activity, spatial memory, and monoaminergic neurotransmitters in ovari-ectomized rats. Neuroscience 113:401-410
11. Bushnell PJ, Levin ED. 1993. Effects of dopaminergic drugs on working and reference memory in rats. Pharmacol Biochem Behav 45:765-776.
12. Conrad CD, Jackson JL, Wieczorek L, Baran SE, Harman JS, Wright RL, Korol DL. 2004. Acute stress impairs spatial memory in male but not female rats: Influence of estrous cycle. Pharmacol Biochem Behav 78:569-579.
13. Curtis AL, Bethea T, Valentino RJ. 2006. Sexually dimorphic responses of the brain norepinephrine system to stress and corticotropin-releasing factor. Neuropsychopharmacology 31:544-554.
14. Deutch AY, Roth RH. 1990. The determinants of stress-induced activation of the prefrontal cortical dopamine system. Prog Brain Res 85:367-403.
15. Dohrenwend BP, Shrout PE, Link BG, Skodol AE, Stueve A. 1995. Life events and other possible risk factors for episodes of schizophrenia and major depression: A case-control study. In: Carolyn Mazure, editor. Does stress cause psychiatric illness? Washington, DC: American Psychiatric Press.
16. Dorow R, Horowski R, Pashelke G, Amin M, Braestrup C. 1983. Severe anxiety induced by FG7142, a B-carboline ligand for benzodiazepine receptors. Lancet:98-99.
17. Funk D, Li Z, Le AD. 2006. Effects of environmental and pharmacological stressors on c-fos and corticotropin-releasing factor mRNA in rat brain: Relationship to the reinstatement of alcohol seeking. Neuroscience 138:235-243.
18. Halbreich U, Lumley LA. 1993. The multiple interactional biological processes that might lead to depression and gender differences in its appearance. J Affect Disord 29:159-173.
19. Ida Y, Elsworth J, Roth RH. 1991. Anxiogenic beta carboline FG7142 produces activation of NE neurons in specific brain regions of rats. Pharmacol Biochem Behav 39:791-793.
20. Izquierdo LA, Barros DM, Medina JH, Izquierdo I. 2002. Stress hormones enhance retrieval of fear conditioning acquired either one day or many months before. Behav Pharmacol 13:203-213.
21. Karkanias GB, Li CS, Etgen AM. 1997. Estradiol reduction of alpha-2-adrenoceptor binding in female rat cortex is correlated with decreases in alpha2A/D-adrenoceptor messenger RNA. Neuroscience 81:593-597.
22. Kelly MJ, Lagrange AH, Wagner EJ, Ronnekleiv OK. 1999. Rapid effects of estrogen to modulate G protein-coupled receptors via activation of protein kinase A and protein kinase C pathways. Steroids 64:64-75.
23. Koenen KC, Driver KL, Oscar-Berman M, Wolfe J, Folsom S, Huang MT, Schlesinger L. 2001. Measures of prefrontal system dysfunction in posttraumatic stress disorder. Brain Cogn 45: 64-78.
24. Larsen JK, Divac I. 1978. Selective ablations within the prefrontal cortex of the rat and performance of delayed alternation. Physiol Psychol 6:15-17.
25. Lee SJ, Camponmanes CR, Sikat PT, Greenfield AT, Allen PB, McEwen BS. 2004. Estrogen induces phosphorylation on cyclic AMP response element binding (pCREB) in primary hippo-campal cells in a time-dependent manner. Neuroscience 124: 549-560.
26. Mazure CM. 1998. Life stressors as risk factors in depression. Clin Psychol Sci Pract 5:291-313.
27. McEwen BS. 2000. Effects of adverse experiences for brain structure and function. Biol Psychiatry 48:721-731.
28. McGinnis MY, Krey LC, MacLusky NJ, McEwen BS. 1981. Steroid receptor levels in intact and ovariectomized estrogen-treated rats: An examination of quantitative, temporal and endocrine factors influencing the efficacy of an estradiol stimulus. Neuroendocrinology 33:158-165.
29. Mikkelsen JD, Soderman A, Kiss A, Mirza N. 2005. Effects of benzodiazepines receptor agonists on the hypothalamic-pituitary-adrenocortical axis. Eur J Pharmacol 519:223-230.
30. Milner TA, Lee A, Aicher SA, Rosin DL. 1998. Hippocampal alpha2a-adrenergic receptors are located predominantly presynaptically but are also found postsynaptically and in selective astrocytes. J Comp Neurol 395:310-327.
31. Mizoguchi K, Yuzuihara M, Ishige A, Sasaki H, Chui D-H, Tabira T. 2000. Chronic stress induces impairment of spatial working memory due to prefrontal dopaminergic dysfunction. J Neurosci 20:1568-1575.
32. Murphy BL, Arnsten AFT, Jentsch JD, Roth RH. 1996. Dopamine and spatial working memory in rats and monkeys: Pharmacological reversal of stress-induced impairment. J Neurosci 16:7768-7775.
33. Ramos BP, Stark D, Verduzco L, van Dyck CH, Arnsten AF. 2006. Alpha2A-adrenoceptor stimulation improves prefrontal cortical regulation of behavior through inhibition of cAMP signaling in aging animals. Learn Mem 13:770-776.
34. Shansky RM, Glavis-Bloom C, Lerman D, McRae P, Benson C, Miller K, Cosand L, Horvath TL, Arnsten AFT. 2004. Estrogen mediates sex differences in stress-induced prefrontal cortex dysfunction. Mol Psychiatry 9:531-538.
35. Shansky RM, Rubinow K, Brennan A, Arnsten AF. 2006. The effects of sex and hormonal status on restraint-stress-induced working memory impairment. Behav Brain Funct 2:8.
36. Shors TJ. 2001. Acute stress rapidly and persistently enhances memory formation in the male rat. Neurobiol Learn Mem 75:10-29.
37. Taylor JR, Birnbaum SG, UbrianiR, Arnsten AFT. 1999. Activation of protein kinase A in prefrontal cortex impairs working memory performance. J Neurosci (Online) 19:RC23.
38. VijayraghavanS, WangM,Birnbaum SG, Williams GV, Arnsten AF. 2007. Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory. Nat Neurosci 10: 376-384.
39. Wang M, Ramos BP, Paspalas CD, Shu Y, Simen A, Duque A, Vijayraghavan S, Brennan A, Dudley A, Nou E, Mazer JA, McCormick DA, Arnsten AF. 2007. Alpha2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex. Cell 129:397-410.
40. Weissman MM, Bland RC, Canino GJ, Faravelli C, Greenwald S, Hwu HG, Joyce PR, Karam EG, Lee CK, Lellouch J, Lepine JP, Newman SC, Rubio-Stipec M, Wells JE, Wickramaratne PJ, Wittchen H, Yeh EK. 1996. Cross-national epidemiology of major depression and bipolar disorder. JAMA 276:293-299.
41. Wood GE, Shors TJ. 1998. Stress facilitates classical conditioning in males, but impairs classical conditioning in females through activational effects of ovarian hormones. Proc Natl Acad Sci USA 95:4066-4071.
42. Zahrt J, Taylor JR, Arnsten AFT. 1996. Supranormal stimulation of dopamine D1 receptors in the prefrontal cortex impairs spatial working memory in rats. Soc Neurosci Abstr 22:1128.
43. Zahrt J, Taylor JR, Mathew RG, Arnsten AFT. 1997. Supranormal stimulation of dopamine D1 receptors in the rodent prefrontal cortex impairs spatial working memory performance. J Neurosci 17:8528-8535.
44. Zubieta JK, Chinitz JA, Lombardi U, Fig LM, Cameron OG, Liberzon I. 1999. Medial frontal cortex involvement in PTSD symptoms: A SPECT study. J Psychiatr Res 33:259-264.