메뉴 건너뛰기




Volumn 89, Issue 12, 2009, Pages 1355-1363

Highly active antiretroviral therapy drugs inhibit in vitro cholesterol efflux from human macrophage-derived foam cells

Author keywords

Antioxidant; Cholesterol efflux; Ginsenosides; HAART; Macrophage; Superoxide anion

Indexed keywords

ALLIIN; ALPHA TOCOPHEROL; ANTIRETROVIRUS AGENT; APOLIPOPROTEIN A1; CAVEOLIN 1; CHOLESTEROL; DIDANOSINE; GINSENOSIDE RB 1; GINSENOSIDE RG 1; INDINAVIR; PROTEIN P67 PHOX; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SIMVASTATIN; STAVUDINE; SUPEROXIDE; UNCLASSIFIED DRUG;

EID: 70549097326     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2009.85     Document Type: Article
Times cited : (14)

References (36)
  • 2
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators
    • Palella Jr FJ, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 1998;338:853-860.
    • (1998) N Engl J Med , vol.338 , pp. 853-860
    • Palella Jr, F.J.1    Delaney, K.M.2    Moorman, A.C.3
  • 3
    • 34247155694 scopus 로고    scopus 로고
    • Molecular mechanisms of HIV protease inhibitor-induced endothelial dysfunction
    • Wang X, Chai H, Yao Q, et al. Molecular mechanisms of HIV protease inhibitor-induced endothelial dysfunction. J Acquir Immune Defic Syndr 2007;44:493-499.
    • (2007) J Acquir Immune Defic Syndr , vol.44 , pp. 493-499
    • Wang, X.1    Chai, H.2    Yao, Q.3
  • 4
    • 34547689728 scopus 로고    scopus 로고
    • Human immunodeficiency virus protease inhibitor ritonavir inhibits cholesterol efflux from human macrophage-derived foam cells
    • Wang X, Mu H, Chai H, et al. Human immunodeficiency virus protease inhibitor ritonavir inhibits cholesterol efflux from human macrophage-derived foam cells. Am J Pathol 2007;171:304-314.
    • (2007) Am J Pathol , vol.171 , pp. 304-314
    • Wang, X.1    Mu, H.2    Chai, H.3
  • 5
    • 0037312029 scopus 로고    scopus 로고
    • HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages
    • Dressman J, Kincer J, Matveev SV, et al. HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages. J Clin Invest 2003;111:389-397.
    • (2003) J Clin Invest , vol.111 , pp. 389-397
    • Dressman, J.1    Kincer, J.2    Matveev, S.V.3
  • 6
    • 0035902493 scopus 로고    scopus 로고
    • Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction
    • Stein JH, Klein MA, Bellehumeur JL, et al. Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction. Circulation 2001;104:257-262.
    • (2001) Circulation , vol.104 , pp. 257-262
    • Stein, J.H.1    Klein, M.A.2    Bellehumeur, J.L.3
  • 7
    • 34047164957 scopus 로고    scopus 로고
    • Cardiovascular risks of antiretroviral therapies
    • Mondy K, Tebas P. Cardiovascular risks of antiretroviral therapies. Annu Rev Med 2007;58:141-155.
    • (2007) Annu Rev Med , vol.58 , pp. 141-155
    • Mondy, K.1    Tebas, P.2
  • 8
    • 0032493043 scopus 로고    scopus 로고
    • A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors
    • Carr A, Samaras K, Burton S, et al. A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors. AIDS 1998;12:F51-F58.
    • (1998) AIDS , vol.12
    • Carr, A.1    Samaras, K.2    Burton, S.3
  • 9
    • 0345064200 scopus 로고    scopus 로고
    • Combination antiretroviral therapy and the risk of myocardial infarction
    • Friis-Moller N, Sabin CA, Weber R, et al. Combination antiretroviral therapy and the risk of myocardial infarction. N Engl J Med 2003;349:1993-2003.
    • (2003) N Engl J Med , vol.349 , pp. 1993-2003
    • Friis-Moller, N.1    Sabin, C.A.2    Weber, R.3
  • 10
    • 33645088471 scopus 로고    scopus 로고
    • Subclinical carotid atherosclerosis in HIV-infected patients: Role of combination antiretroviral therapy
    • Jerico C, Knobel H, Calvo N, et al. Subclinical carotid atherosclerosis in HIV-infected patients: role of combination antiretroviral therapy. Stroke 2006;37:812-817.
    • (2006) Stroke , vol.37 , pp. 812-817
    • Jerico, C.1    Knobel, H.2    Calvo, N.3
  • 11
    • 19644397572 scopus 로고    scopus 로고
    • Effects of HIV protease inhibitor ritonavir on vasomotor function and endothelial nitric oxide synthase expression
    • Fu W, Chai H, Yao Q, et al. Effects of HIV protease inhibitor ritonavir on vasomotor function and endothelial nitric oxide synthase expression. J Acquir Immune Defic Syndr 2005;39:152-158.
    • (2005) J Acquir Immune Defic Syndr , vol.39 , pp. 152-158
    • Fu, W.1    Chai, H.2    Yao, Q.3
  • 12
    • 24144432810 scopus 로고    scopus 로고
    • Effects of 5 HIV protease inhibitors on vasomotor function and superoxide anion production in porcine coronary arteries
    • Chai H, Yang H, Yan S, et al. Effects of 5 HIV protease inhibitors on vasomotor function and superoxide anion production in porcine coronary arteries. J Acquir Immune Defic Syndr 2005;40:12-19.
    • (2005) J Acquir Immune Defic Syndr , vol.40 , pp. 12-19
    • Chai, H.1    Yang, H.2    Yan, S.3
  • 13
    • 30444447501 scopus 로고    scopus 로고
    • Reverse cholesterol transport and cholesterol efflux in atherosclerosis
    • Ohashi R, Mu H, Wang X, et al. Reverse cholesterol transport and cholesterol efflux in atherosclerosis. QJM 2005;98:845-856.
    • (2005) QJM , vol.98 , pp. 845-856
    • Ohashi, R.1    Mu, H.2    Wang, X.3
  • 14
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990's
    • Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990's. Nature 1993;362:801-809.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 15
    • 1242283935 scopus 로고    scopus 로고
    • Triglyceride-rich lipoproteins inhibit cholesterol efflux to apolipoprotein (apo) A1 from human macrophage foam cells
    • Palmer AM, Murphy N, Graham A. Triglyceride-rich lipoproteins inhibit cholesterol efflux to apolipoprotein (apo) A1 from human macrophage foam cells. Atherosclerosis 2004;173:27-38.
    • (2004) Atherosclerosis , vol.173 , pp. 27-38
    • Palmer, A.M.1    Murphy, N.2    Graham, A.3
  • 16
    • 3142514664 scopus 로고    scopus 로고
    • Combination therapy for patients with HIV-1 infection: The use of dual nucleoside analogues with protease inhibitors and other agents
    • Gulick R. Combination therapy for patients with HIV-1 infection: the use of dual nucleoside analogues with protease inhibitors and other agents. AIDS 1998;12(Suppl 3):S17-S22.
    • (1998) AIDS , vol.12 , Issue.SUPPL 3
    • Gulick, R.1
  • 17
    • 0035963902 scopus 로고    scopus 로고
    • Caveolae and intracellular trafficking of cholesterol
    • Fielding CJ, Fielding PE. Caveolae and intracellular trafficking of cholesterol. Adv Drug Deliv Rev 2001;49:251-264.
    • (2001) Adv Drug Deliv Rev , vol.49 , pp. 251-264
    • Fielding, C.J.1    Fielding, P.E.2
  • 18
    • 0034525362 scopus 로고    scopus 로고
    • Involvement of caveolin-1 in cholesterol enrichment of high-density lipoprotein during its assembly by apolipoprotein and THP-1 cells
    • Arakawa R, Abe-Dohmae S, Asai M, et al. Involvement of caveolin-1 in cholesterol enrichment of high-density lipoprotein during its assembly by apolipoprotein and THP-1 cells. J Lipid Res 2000;41: 1952-1962.
    • (2000) J Lipid Res , vol.41 , pp. 1952-1962
    • Arakawa, R.1    Abe-Dohmae, S.2    Asai, M.3
  • 19
    • 34447531942 scopus 로고    scopus 로고
    • Molecular interaction between caveolin-1 and ABCA1 on high-density lipoprotein-mediated cholesterol efflux in aortic endothelial cells
    • Lin YC, Ma C, Hsu WC, et al. Molecular interaction between caveolin-1 and ABCA1 on high-density lipoprotein-mediated cholesterol efflux in aortic endothelial cells. Cardiovasc Res 2007;75:575-583.
    • (2007) Cardiovasc Res , vol.75 , pp. 575-583
    • Lin, Y.C.1    Ma, C.2    Hsu, W.C.3
  • 20
    • 0029799891 scopus 로고    scopus 로고
    • A role for caveolin in transport of cholesterol from endoplasmic reticulum to plasma membrane
    • Smart EJ, Ying Y, Donzell WC, et al. A role for caveolin in transport of cholesterol from endoplasmic reticulum to plasma membrane. J Biol Chem 1996;271:29427-29435.
    • (1996) J Biol Chem , vol.271 , pp. 29427-29435
    • Smart, E.J.1    Ying, Y.2    Donzell, W.C.3
  • 21
    • 33751062798 scopus 로고    scopus 로고
    • Human immunodeficiency virus impairs reverse cholesterol transport from macrophages
    • Mujawar Z, Rose H, Morrow MP, et al. Human immunodeficiency virus impairs reverse cholesterol transport from macrophages. PLoS Biol 2006;4:e365.
    • (2006) PLoS Biol , vol.4
    • Mujawar, Z.1    Rose, H.2    Morrow, M.P.3
  • 22
    • 4644305196 scopus 로고    scopus 로고
    • Modulation of oxidant and antioxidant enzyme expression and function in vascular cells
    • Wassmann S, Wassmann K, Nickenig G. Modulation of oxidant and antioxidant enzyme expression and function in vascular cells. Hypertension 2004;44:381-386.
    • (2004) Hypertension , vol.44 , pp. 381-386
    • Wassmann, S.1    Wassmann, K.2    Nickenig, G.3
  • 23
    • 4344616558 scopus 로고    scopus 로고
    • Role of oxidative stress in coronary heart disease
    • Chen J, Mehta JL. Role of oxidative stress in coronary heart disease. Indian Heart J 2004;56:163-173.
    • (2004) Indian Heart J , vol.56 , pp. 163-173
    • Chen, J.1    Mehta, J.L.2
  • 24
    • 6044220126 scopus 로고    scopus 로고
    • HAART drugs induce oxidative stress in human endothelial cells and increase endothelial recruitment of mononuclear cells: Exacerbation by inflammatory cytokines and amelioration by antioxidants
    • Mondal D, Pradhan L, Ali M, et al. HAART drugs induce oxidative stress in human endothelial cells and increase endothelial recruitment of mononuclear cells: exacerbation by inflammatory cytokines and amelioration by antioxidants. Cardiovasc Toxicol 2004;4: 287-302.
    • (2004) Cardiovasc Toxicol , vol.4 , pp. 287-302
    • Mondal, D.1    Pradhan, L.2    Ali, M.3
  • 25
    • 9244250383 scopus 로고    scopus 로고
    • HAART drugs induce mitochondrial damage and intercellular gaps and gp120 causes apoptosis
    • Fiala M, Murphy T, MacDougall J, et al. HAART drugs induce mitochondrial damage and intercellular gaps and gp120 causes apoptosis. Cardiovasc Toxicol 2004;4:327-337.
    • (2004) Cardiovasc Toxicol , vol.4 , pp. 327-337
    • Fiala, M.1    Murphy, T.2    MacDougall, J.3
  • 26
    • 4444239425 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of ginseng root for cardiovascular disease
    • Zhou W, Chai H, Lin PH, et al. Molecular mechanisms and clinical applications of ginseng root for cardiovascular disease. Med Sci Monit 2004;10:RA187-RA192. (Pubitemid 39166444)
    • (2004) Medical Science Monitor , vol.10 , Issue.8
    • Zhou, W.1    Chai, H.2    Lin, P.H.3    Lumsden, A.B.4    Yao, Q.5    Chen, C.6
  • 27
    • 9044251597 scopus 로고    scopus 로고
    • Antiperoxide effect of S-allyl cysteine sulfoxide, an insulin secretagogue, in diabetic rats
    • Augusti KT, Sheela CG. Antiperoxide effect of S-allyl cysteine sulfoxide, an insulin secretagogue, in diabetic rats. Experientia 1996;52:115-120.
    • (1996) Experientia , vol.52 , pp. 115-120
    • Augusti, K.T.1    Sheela, C.G.2
  • 28
    • 34547587360 scopus 로고    scopus 로고
    • Beneficial effects of statins on endothelial dysfunction and vascular stiffness
    • Dilaveris P, Giannopoulos G, Riga M, et al. Beneficial effects of statins on endothelial dysfunction and vascular stiffness. Curr Vasc Pharmacol 2007;5:227-237.
    • (2007) Curr Vasc Pharmacol , vol.5 , pp. 227-237
    • Dilaveris, P.1    Giannopoulos, G.2    Riga, M.3
  • 29
    • 14944347637 scopus 로고    scopus 로고
    • Vitamin e modulation of cardiovascular disease
    • Meydani M. Vitamin E modulation of cardiovascular disease. Ann N Y Acad Sci 2004;1031:271-279.
    • (2004) Ann N y Acad Sci , vol.1031 , pp. 271-279
    • Meydani, M.1
  • 30
    • 21244456905 scopus 로고    scopus 로고
    • Endothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells: Role of ETB receptor, NADPH oxidase and caveolin-1
    • Dong F, Zhang X, Wold LE, et al. Endothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells: role of ETB receptor, NADPH oxidase and caveolin-1. Br J Pharmacol 2005;145:323-333.
    • (2005) Br J Pharmacol , vol.145 , pp. 323-333
    • Dong, F.1    Zhang, X.2    Wold, L.E.3
  • 31
    • 33847016018 scopus 로고    scopus 로고
    • High glucose downregulates the number of caveolae in monocytes through oxidative stress from NADPH oxidase: Implications for atherosclerosis
    • Hayashi T, Juliet PA, Miyazaki A, et al. High glucose downregulates the number of caveolae in monocytes through oxidative stress from NADPH oxidase: implications for atherosclerosis. Biochim Biophys Acta 2007;1772:364-372.
    • (2007) Biochim Biophys Acta , vol.1772 , pp. 364-372
    • Hayashi, T.1    Juliet, P.A.2    Miyazaki, A.3
  • 32
    • 30344443934 scopus 로고    scopus 로고
    • Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: Role of nitric oxide and p53
    • Mousa AS, Mousa SA. Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53. Nutr Cancer 2005;53:104-110.
    • (2005) Nutr Cancer , vol.53 , pp. 104-110
    • Mousa, A.S.1    Mousa, S.A.2
  • 33
    • 23244435220 scopus 로고    scopus 로고
    • Vitamin e increases production of vasodilator prostanoids in human aortic endothelial cells through opposing effects on cyclooxygenase-2 and phospholipase A2
    • Wu D, Liu L, Meydani M, et al. Vitamin E increases production of vasodilator prostanoids in human aortic endothelial cells through opposing effects on cyclooxygenase-2 and phospholipase A2. J Nutr 2005;135:1847-1853.
    • (2005) J Nutr , vol.135 , pp. 1847-1853
    • Wu, D.1    Liu, L.2    Meydani, M.3
  • 34
    • 33748086021 scopus 로고    scopus 로고
    • Simvastatin induces heat shock factor 1 in vascular endothelial cells
    • Uchiyama T, Atsuta H, Utsugi T, et al. Simvastatin induces heat shock factor 1 in vascular endothelial cells. Atherosclerosis 2006;188:265-273.
    • (2006) Atherosclerosis , vol.188 , pp. 265-273
    • Uchiyama, T.1    Atsuta, H.2    Utsugi, T.3
  • 35
    • 33644684441 scopus 로고    scopus 로고
    • Plasma ascorbic acid concentrations and fat distribution in 19 068 British men and women in the European Prospective Investigation into Cancer and Nutrition Norfolk cohort study
    • Canoy D, Wareham N, Welch A, et al. Plasma ascorbic acid concentrations and fat distribution in 19 068 British men and women in the European Prospective Investigation into Cancer and Nutrition Norfolk cohort study. Am J Clin Nutr 2005;82: 1203-1209.
    • (2005) Am J Clin Nutr , vol.82 , pp. 1203-1209
    • Canoy, D.1    Wareham, N.2    Welch, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.