Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction

Circulation

Volumn 104, Issue 3, 2001, Pages 257-262

  Stein, James H ^a   Klein, Melissa A ^a   Bellehumeur, Jennifer L ^a   McBride, Patrick E ^a   Wiebe, Donald A ^a   Otvos, James D ^b   Sosman, James M ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b LIPOSCIENCE INC   (United States)

Author keywords

Atherosclerosis; Endothelium; Human immunodeficiency virus; Inhibitors; Lipoproteins

Indexed keywords

CHYLOMICRON; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PROTEINASE INHIBITOR; VERY LOW DENSITY LIPOPROTEIN;

ADULT; ANTIVIRAL ACTIVITY; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BRACHIAL ARTERY; CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DYSLIPIDEMIA; ENDOTHELIUM CELL; FEMALE; HELPER CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPERGLYCEMIA; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; MALE; NUCLEAR MAGNETIC RESONANCE; OBESITY; PRIORITY JOURNAL; STATISTICAL ANALYSIS; VASODILATATION;

EID: 0035902493     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.104.3.257     Document Type: Article

References (29)

1. A syndrome of peripheral lipodystrophy, hyperlipidemia and insulin resistance in patients receiving HIV protease inhibitors
2. Visceral abdominal-fat accumulation associated with use of indinavir
3. Severe premature coronary artery disease with protease inhibitors
4. Vascular complications associated with use of HIV protease inhibitors
5. Hyperlipidemia and insulin resistance are induced by protease inhibitors independent of changes in body composition in patients with HIV infection
6. Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: A cohort study
7. Atherogenic dyslipidemia in HIV-infected individuals treated with protease inhibitors
8. The hypertriglyceridemia of acquired immunodeficiency syndrome is associated with an increased prevalence of low density lipoprotein subclass pattern B
9. Measurement of lipoprotein subclass profiles by nuclear magnetic resonance spectroscopy
10. Relation of lipoprotein subclasses as measured by nuclear magnetic resonance spectroscopy to coronary artery disease
11. Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation in patients with coronary artery disease
12. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
13. Non-invasive measurement of human endothelium dependent arterial responses: Accuracy and reproducibility
14. Why permutation tests are superior to t and F tests in biomedical research
15. Associations of HDL 2 and HDL 3 subfractions with ischemic heart disease in men: Prospective results from the Quebec Cardiovascular Study
16. Effect of ritonavir on lipids and post-heparin lipase activities in normal subjects
17. Effects of protease inhibitors on hyperglycemia, hyperlipidemia, and lipodystrophy: A 5-year cohort study
18. Abnormalities of apolipoprotein E in the acquired immunodeficiency syndrome
19. HIV protease inhibitors stimulate hepatic triglyceride stimulus
20. Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction
21. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease
22. Late prognostic value of flow-mediated vasodilation in the brachial artery of patients with chest pain
23. Endothelium-dependent flow-mediated vasodilation in coronary and brachial arteries in suspected coronary artery disease
24. Association of remnant lipoprotein levels with impairment of endothelium-dependent vasomotor function in human coronary arteries
25. Transient triglyceridemia decreases vascular reactivity in young, healthy men without risk factors for coronary heart disease
26. Endothelial dysfunction is detectable in young normotensive fist-degree relatives of subjects with type 2 diabetes in association with insulin resistance
27. The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion
28. Simvastatin, an HMG-coenzyme A reductase inhibitor, improves endothelial function within 1 month
29. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia