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Volumn 39, Issue 2, 2005, Pages 152-158

Effects of HIV protease inhibitor ritonavir on vasomotor function and endothelial nitric oxide synthase expression

Author keywords

Cardiovascular disease; Coronary artery; Endothelial cell; HIV protease inhibitor; Nitric oxide synthase; Porcine; Ritonavir

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; BRADYKININ; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MESSENGER RNA; NITROPRUSSIDE SODIUM; PROTEINASE INHIBITOR; RITONAVIR;

EID: 19644397572     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (38)

References (32)
  • 1
    • 0344826498 scopus 로고    scopus 로고
    • Highly active antiretroviral therapy and the cardiovascular system: The heart of the matter
    • Barbara G. Highly active antiretroviral therapy and the cardiovascular system: the heart of the matter. Pharmacology, 2003;69:177-179.
    • (2003) Pharmacology , vol.69 , pp. 177-179
    • Barbara, G.1
  • 2
    • 0041334066 scopus 로고    scopus 로고
    • Perspectives on HAART: Switch maintenance therapy
    • Leen CL. Perspectives on HAART: switch maintenance therapy. Int J STD AIDS. 2003;14:577-582.
    • (2003) Int J STD AIDS , vol.14 , pp. 577-582
    • Leen, C.L.1
  • 3
    • 0036801281 scopus 로고    scopus 로고
    • HIV infection, antiretroviral therapy and cardiovascular risk
    • Barbaro G. HIV infection, antiretroviral therapy and cardiovascular risk. J Cardiovasc Risk. 2002;9:295-300.
    • (2002) J Cardiovasc Risk , vol.9 , pp. 295-300
    • Barbaro, G.1
  • 4
    • 0142043954 scopus 로고    scopus 로고
    • Association between protease inhibitor use and increased cardiovascular risk in patients infected with human immunodeficiency virus: A systematic review
    • Rhew DC, Bernal M, Aguilar D, et al. Association between protease inhibitor use and increased cardiovascular risk in patients infected with human immunodeficiency virus: a systematic review. Clin Infect Dis. 2003;37:959-972.
    • (2003) Clin Infect Dis , vol.37 , pp. 959-972
    • Rhew, D.C.1    Bernal, M.2    Aguilar, D.3
  • 5
    • 0041589089 scopus 로고    scopus 로고
    • Hyperlipidaemia in patients with HIV-1 infection receiving highly active antiretroviral therapy: Epidemiology, pathogenesis, clinical course and management
    • Calza L, Manfredi R, Chiodo F. Hyperlipidaemia in patients with HIV-1 infection receiving highly active antiretroviral therapy: epidemiology, pathogenesis, clinical course and management. Int J Antimicrob Agents. 2003;22:89-99.
    • (2003) Int J Antimicrob Agents , vol.22 , pp. 89-99
    • Calza, L.1    Manfredi, R.2    Chiodo, F.3
  • 6
    • 0033963686 scopus 로고    scopus 로고
    • Effect of ritonavir on lipids and post-heparin lipase activities in normal subjects
    • Pumell JQ, Zambon A, Knopp RH, et al. Effect of ritonavir on lipids and post-heparin lipase activities in normal subjects. AIDS. 2000;14:51-57.
    • (2000) AIDS , vol.14 , pp. 51-57
    • Pumell, J.Q.1    Zambon, A.2    Knopp, R.H.3
  • 7
    • 0036791645 scopus 로고    scopus 로고
    • HIV protease inhibitor ritonavir induces cytotoxicity of human endothelial cells
    • Zhong DS, Lu XH, Conklin BS, et al. HIV protease inhibitor ritonavir induces cytotoxicity of human endothelial cells. Arterioscler Thromb Vasc Biol. 2002;22:1560-1566.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1560-1566
    • Zhong, D.S.1    Lu, X.H.2    Conklin, B.S.3
  • 8
    • 0035902493 scopus 로고    scopus 로고
    • Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction
    • Stein JH, Klein MA, Bellehumeur JL, et al. Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction. Circulation. 2001;104:257-262.
    • (2001) Circulation , vol.104 , pp. 257-262
    • Stein, J.H.1    Klein, M.A.2    Bellehumeur, J.L.3
  • 9
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 1980;288:373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 10
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med. 1993;329:2002-2012.
    • (1993) N Engl J Med , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 11
    • 0024706628 scopus 로고
    • Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein
    • Ignarro LJ. Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein. Circ Res. 1989; 65:1-21.
    • (1989) Circ Res , vol.65 , pp. 1-21
    • Ignarro, L.J.1
  • 12
    • 0032777665 scopus 로고    scopus 로고
    • Endothelium-derived nitric oxide and vascular physiology and pathology
    • Arnal JF, Dinh-Xuan AT, Pueyo M, et al. Endothelium-derived nitric oxide and vascular physiology and pathology. Cell Mol Life Sci. 1999;55:1078-1087.
    • (1999) Cell Mol Life Sci , vol.55 , pp. 1078-1087
    • Arnal, J.F.1    Dinh-Xuan, A.T.2    Pueyo, M.3
  • 13
    • 0037440731 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase, caveolae and the development of atherosclerosis
    • Shaul PW. Endothelial nitric oxide synthase, caveolae and the development of atherosclerosis. J Physiol. 2003;547:21-33.
    • (2003) J Physiol , vol.547 , pp. 21-33
    • Shaul, P.W.1
  • 14
    • 0033958807 scopus 로고    scopus 로고
    • A new perfusion culture system used to study human vein
    • Surowiec SM, Conklin BS, Li JS, et al. A new perfusion culture system used to study human vein. J Surg Res. 2000;88:34-41.
    • (2000) J Surg Res , vol.88 , pp. 34-41
    • Surowiec, S.M.1    Conklin, B.S.2    Li, J.S.3
  • 15
    • 11144355507 scopus 로고    scopus 로고
    • Estrogen blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries
    • Spencer TA, Chai H, Fu W, et al. Estrogen blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries. J Surg Res. 2004; 118:83-90.
    • (2004) J Surg Res , vol.118 , pp. 83-90
    • Spencer, T.A.1    Chai, H.2    Fu, W.3
  • 16
    • 0142043925 scopus 로고    scopus 로고
    • An open-label, prospective, observational study of the incidence of coronary artery disease in patients with HIV infection receiving highly active antiretroviral therapy
    • Barbaro G, Di Lorenzo G, Cirelli A, et al. An open-label, prospective, observational study of the incidence of coronary artery disease in patients with HIV infection receiving highly active antiretroviral therapy. Clin Ther. 2003;25:2405-2418.
    • (2003) Clin Ther , vol.25 , pp. 2405-2418
    • Barbaro, G.1    Di Lorenzo, G.2    Cirelli, A.3
  • 17
    • 0037187956 scopus 로고    scopus 로고
    • Protease inhibitors and mortality among children and adolescents infected with H1V-1
    • Barbaro G. Protease inhibitors and mortality among children and adolescents infected with H1V-1. N Engl J Med. 2002;346:1026-1027.
    • (2002) N Engl J Med , vol.346 , pp. 1026-1027
    • Barbaro, G.1
  • 18
  • 19
    • 17144463863 scopus 로고    scopus 로고
    • Severe premature coronary artery disease with protease inhibitors
    • Henry K, Melroe H, Huebsch J, et al. Severe premature coronary artery disease with protease inhibitors, Lancet. 1998;351:1328.
    • (1998) Lancet , vol.351 , pp. 1328
    • Henry, K.1    Melroe, H.2    Huebsch, J.3
  • 20
    • 2942605957 scopus 로고    scopus 로고
    • HIV protease inhibitor ritonavir decreases endothelium-dependent vasorelaxation and increases superoxide in porcine arteries
    • Conklin BS, Fu W, Lin PH, et al. HIV protease inhibitor ritonavir decreases endothelium-dependent vasorelaxation and increases superoxide in porcine arteries. Cardiavasc Res. 2004;63:168-175.
    • (2004) Cardiavasc Res , vol.63 , pp. 168-175
    • Conklin, B.S.1    Fu, W.2    Lin, P.H.3
  • 21
    • 0037514194 scopus 로고    scopus 로고
    • Mechanisms of oxidative stress and vascular dysfunction
    • Nedeljkovic ZS, Gokce N, Loscalzo J, Mechanisms of oxidative stress and vascular dysfunction. Postgrad Med J. 2003;79:195-199.
    • (2003) Postgrad Med J , vol.79 , pp. 195-199
    • Nedeljkovic, Z.S.1    Gokce, N.2    Loscalzo, J.3
  • 22
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • Cai H, Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res. 2000;87:840-844.
    • (2000) Circ Res , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 23
    • 0031444666 scopus 로고    scopus 로고
    • Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels
    • Wilcox JN, Subramanian RR. Sundell CL, et al. Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels. Arterioscler Thromb Vasc Biol. 1997;17:2479-2488.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 2479-2488
    • Wilcox, J.N.1    Subramanian, R.R.2    Sundell, C.L.3
  • 24
    • 0034622567 scopus 로고    scopus 로고
    • Characterization of interactions among the heme center, tetrahydrobiopterin, and L-arginine binding sites of ferric eNOS using imidazole, cyanide, and nitric oxide as probes
    • Berka V, Tsai AL. Characterization of interactions among the heme center, tetrahydrobiopterin, and L-arginine binding sites of ferric eNOS using imidazole, cyanide, and nitric oxide as probes. Biochemistry. 2000;39: 9373-9383.
    • (2000) Biochemistry , vol.39 , pp. 9373-9383
    • Berka, V.1    Tsai, A.L.2
  • 25
    • 0026470180 scopus 로고
    • Generation of superoxide by purified brain nitric oxide synthase
    • Pou S, Pou W, Bredt D, et al. Generation of superoxide by purified brain nitric oxide synthase. J Biol Chem. 1992;267:24173-24176.
    • (1992) J Biol Chem , vol.267 , pp. 24173-24176
    • Pou, S.1    Pou, W.2    Bredt, D.3
  • 26
    • 0026058284 scopus 로고
    • Loss of endothelial pertussis toxin-sensitive G protein function in atherosclerotic porcine coronary arteries
    • Shimokawa H, Flavahan NA, Vanhoutte PM. Loss of endothelial pertussis toxin-sensitive G protein function in atherosclerotic porcine coronary arteries. Circulation. 1991;83:652-660.
    • (1991) Circulation , vol.83 , pp. 652-660
    • Shimokawa, H.1    Flavahan, N.A.2    Vanhoutte, P.M.3
  • 27
    • 0031443412 scopus 로고    scopus 로고
    • Endothelial function and oxidant stress
    • Harrison DG. Endothelial function and oxidant stress. Clin Cardiol. 1997;20:II11-II17.
    • (1997) Clin Cardiol , vol.20
    • Harrison, D.G.1
  • 28
    • 0242349764 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular injury: Part II: Animal and human studies
    • Griendling KK, FitzGerald GA. Oxidative stress and cardiovascular injury: part II: animal and human studies, Circulation. 2003;108:2034-2040.
    • (2003) Circulation , vol.108 , pp. 2034-2040
    • Griendling, K.K.1    FitzGerald, G.A.2
  • 29
    • 0142055950 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular injury: Part I: Basic mechanisms and in vivo monitoring of ROS
    • Griendling KK, FitzGerald GA. Oxidative stress and cardiovascular injury: part I: basic mechanisms and in vivo monitoring of ROS. Circulation. 2003;108:1912-1916.
    • (2003) Circulation , vol.108 , pp. 1912-1916
    • Griendling, K.K.1    FitzGerald, G.A.2
  • 30
    • 0035394317 scopus 로고    scopus 로고
    • Apoptotic effects in primary human umbilical vein endothelial cell cultures caused by exposure to virion-associated and cell membrane-associated HIV-1 gp120
    • Huang MB, Khan M, Garcia-Barrio M, et al. Apoptotic effects in primary human umbilical vein endothelial cell cultures caused by exposure to virion-associated and cell membrane-associated HIV-1 gp120. J Acquir Immune Defic Syndr. 2001;27:213-221.
    • (2001) J Acquir Immune Defic Syndr , vol.27 , pp. 213-221
    • Huang, M.B.1    Khan, M.2    Garcia-Barrio, M.3
  • 31
    • 9244250383 scopus 로고    scopus 로고
    • HAART drugs induce mitochondrial damage and intercellular gaps and gp120 causes apoptosis
    • Fiala M, Murphy T, MacDougall J, et al. HAART drugs induce mitochondrial damage and intercellular gaps and gp120 causes apoptosis. Cardiovasc Toxicol. 2004;4:327-338.
    • (2004) Cardiovasc Toxicol , vol.4 , pp. 327-338
    • Fiala, M.1    Murphy, T.2    MacDougall, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.