A novel rat model of abdominal aortic aneurysm using a combination of intraluminal elastase infusion and extraluminal calcium chloride exposure

Journal of Vascular Surgery

Volumn 50, Issue 6, 2009, Pages 1423-1432

  Tanaka, Akiko ^a   Hasegawa, Tomomi ^a   Chen, Zhi ^a   Okita, Yutaka ^a   Okada, Kenji ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHLORIDE; CD11B ANTIGEN; CD3 ANTIGEN; ELASTASE; GELATINASE A; GELATINASE B; INTERLEUKIN 1BETA; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL WALL THICKNESS; ARTICLE; CONTROLLED STUDY; DEATH; DILATION AND EVACUATION; ELASTOLYSIS; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; RELIABILITY; SURGICAL TECHNIQUE; UPREGULATION;

ANIMALS; ANTIGENS, CD11B; ANTIGENS, CD3; AORTA, ABDOMINAL; AORTIC ANEURYSM, ABDOMINAL; CALCIUM CHLORIDE; DISEASE MODELS, ANIMAL; INFLAMMATION; INFUSIONS, INTRA-ARTERIAL; INTERLEUKIN-1BETA; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; PANCREATIC ELASTASE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70549085988     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jvs.2009.08.062     Document Type: Article

References (32)

1. Aoki H., Yoshimura K., and Matsuzaki M. Turning back the clock: regression of abdominal aortic aneurysms via pharmacotherapy. J Mol Med 85 (2007) 1077-1088
2. Longo G.M., Xiong W., Greiner T.C., Zhao Y., Fiotti N., and Baxter B.T. Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J Clin Invest 110 (2002) 625-632
3. Miwa K., Nakashima H., Aoki M., Miyake T., Kawasaki T., Iwai M., et al. Inhibition of ets, an essential transcription factor for angiogenesis, to prevent the development of abdominal aortic aneurysm in a rat model. Gene Ther 12 (2005) 1109-1118
4. Nakashima H., Aoki M., Miyake T., Kawasaki T., Iwai M., Jo N., et al. Inhibition of experimental abdominal aortic aneurysm in the rat by use of decoy oligodeoxynucleotides suppressing activity of nuclear factor kappaB and ets transcription factors. Circulation 109 (2004) 132-138
5. Nataatmadja M., West J., and West M. Overexpression of transforming growth factor-beta is associated with increased hyaluronan content and impairment of repair in Marfan syndrome aortic aneurysm. Circulation 114 (2006) I371-I377
6. Yoshimura K., Aoki H., Ikeda Y., Fujii K., Akiyama N., Furutani A., et al. Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase. Nat Med 11 (2005) 1330-1338
7. Anidjar S., Salzmann J.L., Gentric D., Lagneau P., Camilleri J.P., and Michel J.B. Elastase-induced experimental aneurysms in rats. Circulation 82 (1990) 973-981
8. Gadowski G.R., Ricci M.A., Hendley E.D., and Pilcher D.B. Hypertension accelerates the growth of experimental aortic aneurysms. J Surg Res 54 (1993) 431-436
9. Halpern V.J., Nackman G.B., Gandhi R.H., Irizarry E., Scholes J.V., Ramey W.G., et al. The elastase infusion model of experimental aortic aneurysms: synchrony of induction of endogenous proteinases with matrix destruction and inflammatory cell response. J Vasc Surg 20 (1994) 51-60
10. Holmes D.R., Petrinec D., Wester W., Thompson R.W., and Reilly J.M. Indomethacin prevents elastase-induced abdominal aortic aneurysms in the rat. J Surg Res 63 (1996) 305-309
11. Johanning J.M., Franklin D.P., Han D.C., Carey D.J., and Elmore J.R. Inhibition of inducible nitric oxide synthase limits nitric oxide production and experimental aneurysm expansion. J Vasc Surg 33 (2001) 579-586
12. Sinha I., Pearce C.G., Cho B.S., Hannawa K.K., Roelofs K.J., Stanley J.C., et al. Differential regulation of the superoxide dismutase family in experimental aortic aneurysms and rat aortic explants. J Surg Res 138 (2007) 156-162
13. Carsten III C.G., Calton W.C., Johanning J.M., Armstrong P.J., Franklin D.P., Carey D.J., et al. Elastase is not sufficient to induce experimental abdominal aortic aneurysms. J Vasc Surg 33 (2001) 1255-1262
14. Yamaguchi T., Yokokawa M., Suzuki M., Higashide S., Katoh Y., Sugiyama S., et al. Morphologic changes in the aorta during elastase infusion in the rat aneurysm model. J Surg Res 95 (2001) 161-166
15. Sinha I., Hannawa K.K., Eliason J.L., Ailawadi G., Deogracias M.P., Bethi S., et al. Early MT-1 MMP expression following elastase exposure is associated with increased cleaved MMP-2 activity in experimental rodent aortic aneurysms. Surgery 136 (2004) 176-182
16. Sinha I., Cho B.S., Roelofs K.J., Stanley J.C., Henke P.K., and Upchurch Jr. G.R. Female gender attenuates cytokine and chemokine expression and leukocyte recruitment in experimental rodent abdominal aortic aneurysms. Ann N Y Acad Sci 1085 (2006) 367-379
17. Gertz S.D., Kurgan A., and Eisenberg D. Aneurysm of the rabbit common carotid artery induced by periarterial application of calcium chloride in vivo. J Clin Invest 81 (1988) 649-656
18. Isenburg J.C., Simionescu D.T., Starcher B.C., and Vyavahare N.R. Elastin stabilization for treatment of abdominal aortic aneurysms. Circulation 115 (2007) 1729-1737
19. Institute of Laboratory Animal Research Commission on Life Sciences NR. C. Guide for the care and use of laboratory animals (1996), National Academy Press, Washington, DC
20. Johnston K.W., Rutherford R.B., Tilson M.D., Shah D.M., Hollier L., and Stanley J.C. Suggested standards for reporting on arterial aneurysms. Subcommittee on Reporting Standards for Arterial Aneurysms, Ad Hoc Committee on Reporting Standards, Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery. J Vasc Surg 13 (1991) 452-458
21. Yamaguchi T., Yokokawa M., Suzuki M., Higashide S., Katoh Y., Sugiyama S., et al. Shortened elastase infusion time in the elastase-induced rat aneurysm model. J Surg Res 85 (1999) 158-162
22. Basalyga D.M., Simionescu D.T., Xiong W., Baxter B.T., Starcher B.C., and Vyavahare N.R. Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinases. Circulation 110 (2004) 3480-3487
23. Tsuruda T., Kato J., Hatakeyama K., Kojima K., Yano M., Yano Y., et al. Adventitial mast cells contribute to pathogenesis in the progression of abdominal aortic aneurysm. Circ Res 102 (2008) 1368-1377
24. Kim M.P., Raho V.J., Mak J., and Kaynar A.M. Skin and soft tissue necrosis from calcium chloride in a deicer. J Emerg Med 32 (2007) 41-44
25. Freestone T., Turner R.J., Higman D.J., Lever M.J., and Powell J.T. Influence of hypercholesterolemia and adventitial inflammation on the development of aortic aneurysm in rabbits. Arterioscler Thromb Vasc Biol 17 (1997) 10-17
26. Eliason J.L., Hannawa K.K., Ailawadi G., Sinha I., Ford J.W., Deogracias M.P., et al. Neutrophil depletion inhibits experimental abdominal aortic aneurysm formation. Circulation 112 (2005) 232-240
27. Shimizu K., Mitchell R.N., and Libby P. Inflammation and cellular immune responses in abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol 26 (2006) 987-994
28. Sun J., Sukhova G.K., Yang M., Wolters P.J., MacFarlane L.A., Libby P., et al. Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice. J Clin Invest 117 (2007) 3359-3368
29. Freestone T., Turner R.J., Coady A., Higman D.J., Greenhalgh R.M., and Powell J.T. Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol 15 (1995) 1145-1151
30. Chew D.K., Orshal J.M., and Khalil R.A. Elastase promotes aortic dilation by inhibiting Ca2+ influx into vascular smooth muscle. J Cardiovasc Pharmacol 43 (2004) 504-513
31. Robin J., Kharbanda R., Mclean P., Campbell R., and Vallance P. Protease-activated receptor 2-mediated vasodilatation in humans in vivo: role of nitric oxide and prostanoids. Circulation 107 (2003) 954-959
32. Carrell T.W., Smith A., and Burnand K.G. Experimental techniques and models in the study of the development and treatment of abdominal aortic aneurysm. Br J Surg 86 (1999) 305-312